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' b' p$ q, d5 z# f: q“To regenerate long-lasting liver, we may need to transplant hepatocytes with the properly activated endothelium, which produces the right growth factors for the hepatocytes to attach, grow, and connect with other parts of the liver...It’s all about cross-talk between endothelium and blood cells. Somehow when the number of blood cells decreases, endothelial cells are activated and produce the proper set of growth factors to replenish stem cells and help them regenerate the bone marrow.”--Howard Hughes Medical Institute investigator Shahin Rafii.$ C8 Q" @2 q2 Y; O4 p: [4 m
$ B* p6 F9 V, I y- u: q. I; k"The hallmarks we see with the ageing of muscles just weren't occurring - the transplanted material seemed to kick the stem cells to a high gear for self-renewal, essentially taking over the production of muscle cells."--Professor Bradley Olwin of CU-Boulder's molecular, cellular and developmental biology department of University of Colorado at Boulder./ U9 B; H3 S$ c; B1 R, ~# E! t* a
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“There are a lot of sophisticated aspects of tooth function. But you might not have to form a tooth as perfectly as a heart or kidney in order for it to function adequately.”--Ophir Klein at UCSF.
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J0 f {: N2 b' t“It is high time for this issue to be treated as a national priority. We are well aware that foes of stem cell research will do absolutely everything in their power in court and through legislation to cripple stem cell research. The Stem Cell Action coalition will challenge them at every level. We will not let them crush hope.”--Bernard Siegel, executive director of Genetics Policy Institute.
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“The translation of pre-clinical results into therapies will be an important aspect of stem cell research over the next ten years. Students entering this field should know that it is fascinating, with the opportunity to produce results that can potentially be translated in clinical practice, providing hope in areas where traditional medicine does not offer therapeutic opportunities.”--Dr. Cinzia Rota, from the Mario Negri Institute for Pharmacological Research in Bergamo, Italy.. D3 Q) t4 Q. y0 @2 G1 m T
2 r$ W; Z, W- _) h: k$ j"Science is the process of peeling away the layers of veils concealing the truth from us. When scientists peel away one veil, they find another underneath it. But when a fortunate scientist peels away a particular veil, he or she may suddenly discover the truth. This lucky scientist publishes a paper about his or her discovery in a first-rate scientific journal, and is widely praised for it. But we must never forget that it is equally important to peel away any one of these veils. As such, it is not fair to praise only that lucky scientist."--Shinya Yamanaka.
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0 Q& l" k; U) _7 [: l"The disadvantages of the culture systems commonly used now are that they are undefined – you don't really know what your cells are in contact with – and there is no uniformity, which means there is batch-to-batch variability. The system we've developed is fully defined and inexpensive."--Laura Kiessling, a UW-Madison professor of chemistry.
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3 l" y* u5 J; d; D0 ^* eThis issue: V1 e# H- R4 V/ P5 s
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