Cells can communicate with each other through the8 L* a$ N& k- H
secretion of cytokines, small (8–30 kDa) soluble proteins. 6 B ?! ^; Z5 r: c0 ATo date, roughly 20 cytokines have been identified. Upon( S( m: V6 N8 u9 T% j
binding their cognate receptors, receptor-associated Janus) d+ ] K0 x0 |1 X! [: y' `
Kinases (JAKS) phosphorylate tyrosine residues of the0 b% l) V; j8 m& W1 _
ligand-bound receptors, as well as interacting Signal* M9 Q9 z: @: w, v1 v* i
Transducers and Activators of Transcription (STATs).Tyrosine phosphorylated STATs form homodimers, shuttle) V$ l; E7 g! n% \, g i& W0 m2 m
to the nucleus and participate in transcriptional regulation5 A. [) c, I5 ~, l& ]! V
of a variety of genes ( B v$ x+ M2 p6 W, N& L $ L3 t1 Z3 f4 C# w b3 @我标记的这一句，是什么意思呢 ，为什么我连语法结构都分析不过来呢，总感觉少了点什么！希望热心人给予解答！作者: huangcong1988 时间: 2011-5-30 19:50
回复 a2782953 的帖子$ N4 G! K3 J0 h" V8 p
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通过结合它们的同源受体，同时影响STATs，受体相关的JAKS（主语）磷酸化（胃) 配体-bound受体的酪氨酸残基（宾）。 5 R$ w# n; i, l/ E) n# P. v " @& w) {8 G1 k我的理解是这样的，但是这句话的背景我还是不太了解，所以一些专业相关的词我也不知道怎么翻作者: a2782953 时间: 2011-5-31 07:19
