本帖最后由 FreeCell 于 2011-6-8 15:48 编辑 * p6 T1 f3 ~6 ]" W H! v% L, o) }7 E5 z
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相关研究表明塑化剂可干扰机体内的干细胞正常分化作用， 科学家用白老鼠研究发现曾经服食“塑化剂”的老鼠，诞下的后代以雌性为主，并会影响其正常的排卵；即使诞下雄性，其生殖器官较正常的小三分之二，而精子数量亦大减，反映“塑化剂”毒性属抗雄激素活性，造成内分泌失调，影响其正常生育能力。专家表示，研究可以应用到人类身上，显示长期摄吸“塑化剂”对男性的影响较女性大。[attach]28284[/attach] ( e) u! Y5 M& n" L 8 H4 x" J* u1 [6 m+ x/ SBiemann R, Riemann D, Fischer B and Navarrete Santos A The food contaminants bisphenol A, DEHP and tributyltin affect the adipogenic commitment of mesenchymal stem cells. 6th Copenhagen Workshop on Endocrine Disrupters, 26-29 April 2011, Denmark. + B' [ I% b, x& n! [0 e * x! J& F' n& HBiemann R, Riemann D, Fischer B, Navarrete Santos A Nutritional contaminants like BPA, DEHP and TBT impact adipogenic differentiation of mesenchymal stem cells. XXIV. Bilaterales Symposium "Molecular Medicine", 20-21 May 2011, Germany. % w( `- b5 o# ^8 p9 C6 R+ c+ x1 V( d / B5 S) {: e3 z) ^9 DPerinatal Exposure to the Phthalates DEHP, BBP, and DINP, but Not DEP, DMP, or DOTP, Alters Sexual Differentiation of the Male Rat 2 Z# k6 |6 Y: ?L. Earl Gray Jr.*,1, Joseph Ostby*, Johnathan Furr*, Matthew Price*, D. N. Rao Veeramachaneni† and Louise Parks* ! Q' I% K' l; z0 v! ^Toxicological Sciences Volume58, Issue2 Pp. 350-365. Received May 26, 2000. Accepted July 24, 2000. ) X$ j4 d! Q7 J# [& @/ P2 G; l: M, ^3 ^3 i
The natural progression of this lesion would be fibrosis, resulting in complete atrophy or even complete disappearance of testicular tissue. Notably, differentiating germ stem cells were also affected by DEHP. In PND 2 and PND 3 DEHP-treated animals, multinucleated gonocytes containing as many as 3–5 nuclei and some undergoing degenerative changes were observed. 8 b4 d3 K$ r' `1 o/ a3 E8 @1 m + f" \& D, c8 n& H. u[attach]28283[/attach]作者: FreeCell 时间: 2011-6-8 15:43