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标题: 间充质干细胞可能治疗的主要10种疾病 [打印本页]

作者: sunsong7    时间: 2011-6-20 23:48     标题: 间充质干细胞可能治疗的主要10种疾病

list of top 10 new diseases that can be treated with mesenchymal stem cells:
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7 _. z6 ?' K. [8 h& B$ Q& i引自:http://www.healtharticles101.com ... nchymal-stem-cells/& l  B5 c6 Z% \: U$ f

9 n# S; v1 E2 U0 _( G1. Heart Disease(心脏疾病2 n6 `7 P7 p/ o/ ~  D

' X& e# X. A0 d# wMesenchymal stem cells have shown great promise in treating heart disease. The stem cells can cause damaged tissue to regenerate, leading to better heart function and health. Better blood flow and nutrients may also play a part in this regrowth.* G0 ^' D; a8 f

7 l# h  F/ W2 N* z/ k& ?2. Diabetes(糖尿病' ]/ w9 M! n' V) @

' s- S" [& ]2 f# T; FThe stem cells controversy often overlooks the benefits for diabetes. With stem cells this disease can be reversed, so many diabetics will no longer have to take insulin every day or suffer from other medical conditions caused by this disease. Beta cells can be restored to normal, so diabetes is no longer a problem.
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4 P1 W0 d  C5 u4 m3. Crohn’s Disease(克隆氏病  P+ O: l/ u3 }2 h8 U1 t7 n
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Crohn’s Disease is one of the new diseases that can be treated with mesenchymal stem cells. It is not yet known how these cells benefit your colon and digestive tract during the treatment but clinical trials have shown they can improve this condition significantly.9 O( \+ [8 k9 n) f9 h

+ c( ]6 c) z1 H, _" G4. Deafness(耳聋)2 l. a% K# p) J0 x. H9 ?; N% Z

4 [0 i: [4 l3 {% [& m: QPluripotent stem cells are not the only ones with great promise. The mesenchymal type has been shown to be effective at treating deafness. Cochlear hair cells have regrown after stem cell transplants, leading to hearing being restored.
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2 A4 N$ t& Y9 A( o2 e0 z5. Autoimmune Disorders(自体免疫紊乱
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A large number of new autoimmune disorders can be treated with mesenchymal stem cells. This treatment option is not widely available yet but has been increasing. The number and scope of these diseases continue to rise, and stem cells may be able to reverse this trend.: ~6 I! c1 O# y1 R
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6. Leukemia(白血病)) a! |# I. E/ n; n/ T
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Leukemias and lymphomas can be successfully treated with stem cell transplants, and recent studies have proven this benefit. Often these diseases come back with traditional treatments, but stem cells can replace the defective cells with good ones so that a recurrence is far less likely.
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4 m) S1 Q9 R+ E7. Cancers(癌症% F% T8 ?+ ^+ \0 h4 x0 u5 W0 p
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Mesenchymal stem cells have shown great promise as a treatment for many types of cancer, both common and rare. Breast cancer and many other types have shown to be highly treatable with stem cells, so normal cells are restored and the cancer does not recur.
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; c" w- P5 L* F8 Z: b+ q8. Sickle Cell Disease(镰状细胞疾病)
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Umbilical cord stem cell research has shown that sickle cell disease can be treated with stem cells. The transplanted stem cells can create new normal red blood cells, instead of the crescent shaped ones present in this disease.: O' }3 F0 T& ]) I9 N9 o, c9 D

- a% Q& j1 z) b0 a1 b, I9. Amyotrophic Lateral Sclerosis(肌萎缩性脊髓侧索硬化症
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3 {6 W$ d6 d' }0 }Mesenchymal stem cells have proven to be effective in mice at eliminating Amyotrophic Lateral Sclerosis and related disorders. When mice with this condition where given stem cells the condition disappeared and the mice became normal, with no disease present or detectable.
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+ l8 @" v$ F7 l* A5 A10. Metabolic Disorders(代谢紊乱
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3 ]* K" Y; X9 A7 g# Q' Z% n- m, S# p; POne of the pros of stem cell research is that it has shown these cells are effective at treating metabolic disorders. These diseases are caused by defective genes and cells, and stem cells replace the defective material with normal cells and tissues instead.
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作者: chemchen123    时间: 2011-6-21 00:00

good
作者: 我是丁香    时间: 2011-6-21 00:04

能治疗癌症么?MSC不是诱导免疫耐受么?
作者: 大少爷    时间: 2011-6-21 08:35

可以治疗,但也有个体差异,它也并不是万能的。
作者: 心醉夕阳1    时间: 2011-6-22 11:16

比拼一下:1 _( G8 t5 w0 s! @7 j* B2 k0 W& m
1. Spinal cord injury(脊髓损伤). 神经细胞和胶质细胞的修复和再生" }1 f0 i" p8 u! o1 t5 @9 f
2. Diabetes(糖尿病). 胰岛B细胞和胰腺细胞的再生) f, t$ b" Q( _+ m* I4 u6 B
3. Heart disease(心脏疾病). 心肌细胞和血管平滑肌细胞
1 N% N( f9 u6 C! k' b4. Parkinson’s disease(帕金森综合症). 神经内分泌核团细胞
  Q! M5 d4 a) ~3 X0 \+ d5. Alzheimer’s disease(老年痴呆症).大脑皮层和皮层下神经元细胞 6 i3 L; o3 P- w0 r2 |: G
6. Lou Gehrig’s disease(肌肉萎缩性侧索硬化症).神经-肌肉触点细胞 3 p) ]5 }  {5 u8 @
7. Lung diseases(肺脏疾病). 肺泡和血管平滑肌细胞! |0 y  h3 h6 M$ C1 r
8. Arthritis(关节炎). 关节软骨和成骨细胞% ?: O& z# I, M+ @0 e2 l- l0 t" a
9. Sickle cell anemia(镰状细胞性贫血). 骨髓和红细胞
' M8 d- B+ \  V/ t+ z/ o0 s' ?( w10. Organ failure(器官失能). 细胞层面抗衰老和老化- ], D* T1 ?5 I% k8 X' e3 V
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疾病治疗方面提到了心脑肺胰四个器官; 肌骨血三大组织;没有提肝脏、肾脏;不知道是有难度还是为了避开器官移植的冲击;
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保健方面提到了器官失能,没有强调主要器官,说明对所有器官的细胞失能有效,片面证明了细胞再生抗衰老的应用合理性;
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没有提到免疫系统或者免疫细胞方面的问题,是不是说,干细胞治疗白血病绝对有效,以作和“可能有效、可能治愈”相区别。9 r4 j' v6 p& Q

0 d$ l! o. v& H# r' U上文提到了四种免疫系统疾病,两种消化系统疾病,一种内分泌代谢系统疾病,两种肌肉系统,一种神经系统;整合起来就是  神经-内分泌-免疫网络疾病,也就是自体稳态调节疾病,突出了全身系统的老化管理。没有提到抗衰老,但是步步不离抗衰老。
作者: kgx1986    时间: 2011-6-22 22:17

回复 我是丁香 的帖子4 _# F* L8 b* N) X

) @: S: b0 \9 i4 X我看过一篇文献,MSC对肿瘤有双向作用,即一方面有扼制作用,另一方面促进血管生成肿瘤提供营养,有利于肿瘤生长和转移
作者: beginner    时间: 2011-6-23 10:16

我硕士师姐两年的鼠体内外实验结果是对Hepg2有抑制作用。
/ d- x: z4 G6 x! l" J1 x当然说有促进作用也是有理由的
作者: lizzy_81    时间: 2011-6-24 18:24

回复 kgx1986 的帖子+ H: d) U8 Q: F& f2 ^. r9 U. |
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请问你有这边文献的原文吗,可以发上来吗?或者可以提供一下文献的信息吗
作者: kgx1986    时间: 2011-6-24 21:24

回复 lizzy_81 的帖子5 _8 ~4 _; m; s2 Q6 I
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我还不知道怎样给全文哦
作者: 细胞海洋    时间: 2011-6-25 11:50

回复 kgx1986 的帖子
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回复 高级模式 附件上传
作者: chen1988    时间: 2012-11-1 21:17

很多免疫系统疾病都有辅助作用
作者: jensn    时间: 2012-11-20 09:46

干细胞的确给人类打开了一扇希望的大门,但是干细胞也是一种生命物质,也需要遵循能量、物质的物理定律,如果过于痴迷其永生性和自我更新潜能,只怕会将干细胞的研究引向一个歧途。




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