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目录： - ~: v8 h6 s3 G ^3 s4 pIn This Issue( I8 F9 N# u/ t& [
In This Issue p489 3 ~; C3 h' ?& b4 v/ m + J U; H. K" u! i. X% q3 p) `Select ( L7 H$ G% E. V) @/ Z$ d6 JRemote Control: The Brain and Beyond p493 5 m; M& ?/ m, O; j, B+ D ! l: G7 x* k5 O5 \) S" ^Previews 6 y% m. N9 I O1 g0 ~9 ITranscription Factor Loading: Please Take My Place! p497 ; k) `" b' A; i
Markus Stratmann, Ueli Schibler h8 x6 e' ^& l. e- W! NTravel Notes from the Equatorial Circle p499 " M! T) t' _& D6 J4 kAndrea Musacchio + O1 F; B; R# d _( z! }Elongated Membrane Zones Boost Interactions of Diffusing Proteins p501 - C# I! d2 n" E I& Z
Joshua Zimmerberg, Samuel T. Hess/ W3 t- u# @& D% V: C
Meeting the (N-Terminal) End with Acetylation p503 " a. y- J/ x# u' ^7 cJoshua L. Andersen, Sally Kornbluth ; { w( Z3 j# A% D* Z; } " O5 g* n: l# S* }. HCommentary ) w+ ]. r ~7 m3 |+ m! q# UOrganizing Graduate Life Sciences Education around Nodes and Connections p506 ; O- u6 ^. B4 m$ G7 fJon R. Lorsch, David G. Nichols4 v' h6 G6 ~ A* F
- ~; s/ J7 f/ S6 w8 p Perspective 8 |6 z& a! G( @+ r; jMechanisms for the Inheritance of Chromatin States p510 5 @& y; w" Y7 t2 m& y, \
Danesh Moazed , `" W2 }1 A% e, N# S/ {+ m' E/ i0 {/ m& I% w4 z7 a/ U Articles ! q8 s7 B0 t- I8 [6 y$ w0 iReconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells p519 , ~0 C* ?# F) z5 ~, v% M: S4 s" h( K
Katsuhiko Hayashi, Hiroshi Ohta, Kazuki Kurimoto, Shinya Aramaki, Mitinori Saitou 7 q' R4 ]/ e% y) ]Linking RNA Polymerase Backtracking to Genome Instability in E. coli p533 5 U( y0 X# _9 T- s# ~8 g
Dipak Dutta, Konstantin Shatalin, Vitaly Epshtein, Max E. Gottesman, Evgeny Nudler 8 p( s' s" `% cDynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism p544 ' S' P" G4 o! Y! I4 S) YTy C. Voss, R. Louis Schiltz, Myong-Hee Sung, Paul M. Yen, John A. Stamatoyannopoulos, Simon C. Biddie, Thomas A. Johnson, Tina B. Miranda, Sam John, Gordon L. Hager+ g9 W( e1 v, s% B9 M! a
The Spatial Arrangement of Chromosomes during Prometaphase Facilitates Spindle Assembly p555 2 z4 y/ w5 P& X% h9 c
Valentin Magidson, Christopher B. O'Connell, Jadranka Lon?arek, Raja Paul, Alex Mogilner, Alexey Khodjakov' {9 h$ m( Y g9 e$ J, x* q, I) h; j
Complete Kinetochore Tracking Reveals Error-Prone Homologous Chromosome Biorientation in Mammalian Oocytes p568 ' O; x) Z+ S! Q1 T) U' cTomoya S. Kitajima, Miho Ohsugi, Jan Ellenberg 1 o- @5 e$ N0 x/ G! YRapid Microtubule Self-Assembly Kinetics p582 ( D* {( @) [& N* A* W% G4 P
Melissa K. Gardner, Blake D. Charlebois, Imre M. Jánosi, Jonathon Howard, Alan J. Hunt, David J. Odde9 n; \1 F/ _: r2 }2 L5 G8 Q
Cytoskeletal Control of CD36 Diffusion Promotes Its Receptor and Signaling Function p593 $ {% P: d I' j* i* d; CKhuloud Jaqaman, Hirotaka Kuwata, Nicolas Touret, Richard Collins, William S. Trimble, Gaudenz Danuser, Sergio Grinstein # I9 {# u. t' J8 x1 H m& m, ~2 a0 I& jMetabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival p607 $ n2 e2 m x( D% Y+ z cCaroline H. Yi, Heling Pan, Jan Seebacher, Il-Ho Jang, Sven G. Hyberts, Gregory J. Heffron, Matthew G. Vander Heiden, Renliang Yang, Fupeng Li, Jason W. Locasale, Hadar Sharfi, Bo Zhai, Ricard Rodriguez-Mias, Harry Luithardt, Lewis C. Cantley, George Q. Daley, John M. Asara, Steven P. Gygi, Gerhard Wagner, Chuan-Fa Liu, Junying Yuan + u2 f$ I; e% [. ?( h8 D( O& O) UStructural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons p621 0 `( z& @" f- F, p' o% i
Christoph Thomas, Ignacio Moraga, Doron Levin, Peter O. Krutzik, Yulia Podoplelova, Angelica Trejo, Choongho Lee, Ganit Yarden, Susan E. Vleck, Jeffrey S. Glenn, Garry P. Nolan, Jacob Piehler, Gideon Schreiber, K. Christopher Garcia8 W. U# F. n) l: z4 k3 d' M0 D- x4 f
9 @+ t- W1 q/ \Theory : o1 R+ E+ E) y; H* vStochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells p633 + O1 x2 c, V: b9 a- O1 M- `Piyush B. Gupta, Christine M. Fillmore, Guozhi Jiang, Sagi D. Shapira, Kai Tao, Charlotte Kuperwasser, Eric S. Lander % W D9 l' i* L* ]# ^. x% W6 i ( u3 }) o" C. t' j: Q* BResource- s+ h/ d. g6 \# y
The Human Mitochondrial Transcriptome p645 - b P3 w8 W; j( X- `) }
Tim R. Mercer, Shane Neph, Marcel E. Dinger, Joanna Crawford, Martin A. Smith, Anne-Marie J. Shearwood, Eric Haugen, Cameron P. Bracken, Oliver Rackham, John A. Stamatoyannopoulos, Aleksandra Filipovska, John S. Mattick * E" D" _+ l! l& S, R6 ^8 I, H1 l' ^4 Q' m! Q Erratum9 p2 m7 H% i9 G) ~% t
Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations p659 & }- N8 ~& m, G8 V$ j/ QFrank Soldner, Josée Laganière, Albert W. Cheng, Dirk Hockemeyer, Qing Gao, Raaji Alagappan, Vikram Khurana, Lawrence I. Golbe, Richard H. Myers, Susan Lindquist, Lei Zhang, Dmitry Guschin, Lauren K. Fong, B. Joseph Vu, Xiangdong Meng, Fyodor D. Urnov, Edward J. Rebar, Philip D. Gregory, H. Steve Zhang, Rudolf Jaenisch 7 g; Y& a6 d5 T# A* W r/ z5 H& ` 4 m' t8 {) C* ]* GSnapshot $ z. W: ~4 M! w0 J# M! j1 xSnapShot: Dendritic Cells p660 7 ]/ h* @) }$ a- @3 }6 e
Juliana Idoyaga, Ralph M. Steinman 8 n/ ?+ M |7 v5 W; O4 u1 |$ m, q5 _ n+ D- b6 {' I b 压缩文件内是一个一个的pdf文件和封面照片。+ M* @/ a! _3 K
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