histone H3& h2 }) u; M. o1 x9 [
methylation at lysine 9 is associated with heterochromatin and 2 v/ Y, N! v2 q/ d# F! A9 @: Qgene silencing, while histone H3 at lysine 4 or 27 is associated ( v! ^+ u) A: O( u* K3 @8 d) twith transcriptional activation. 5 V0 T) M0 ^5 a% |) z% T d: v* n% L" y9 m
Each lysine residue may be ! ^3 e7 t" b- K; g. w5 q5 n, l" {: jmethylated in the form of mono-, di-, or tri-methylation, adding + |) {, O. B z$ \ ?enormous complexity. Deciphering histone tail modifications 6 i" b+ K# x7 B6 ?and defining a potential “histone code” controlling gene expression- m3 H+ s* ]0 x* C
represents an emerging field of epigenetic research 。 b1 G% S5 u* U+ g7 K% UWhether the potential histone code is modifiable by environmental 4 t x* L) {. q7 F% `) [$ Mexposures, similar toDNAmethylation patterns, remains . n' q( g# z ~$ X' _+ l- ~to be determined.8 X. X- f- C, q% b- K2 g" o8 T
可以的话请把汉语写下来,谢谢。里面有些术语我都不知道翻成什么。作者: webber43 时间: 2011-9-5 21:10