/ K, h$ V- Y O) u; P" L9 ]4 NOn the cover: A flood of discoveries expanding not only the different classes of regulatory RNAs but also revealing a variety of distinct regulatory roles has changed how we think about these nucleic acids and their biological functions. From their ability to base pair with other nucleic acids and serve as scaffolds for protein complexes to their dynamic structure and catalytic activity, the properties of RNAs make them ideal regulatory molecules. Our knowledge of the diversity of these RNA-based mechanisms continues to grow, as does our understanding of the critical pathways and processes they impact. This image depicts some of these RNAs—thermosensors, tRNAs, and riboswitches—showing them emerging from the background as central regulatory elements, making an indelible stamp on molecular biology. Cover art by Yvonne Blanco.% O$ B3 M% P) K) N" d
* U3 Z9 ^* c; Q
8 T) s: L) E o- _
