标题: 求文献：Cell fusion hypothesis of the cancer stem cell. [打印本页] 作者: sunsong7 时间: 2012-2-26 15:22 标题: 求文献：Cell fusion hypothesis of the cancer stem cell.
Adv Exp Med Biol. 2011;714:129-40. ( M# R& Y* I: v* I3 H5 k$ OCell fusion hypothesis of the cancer stem cell.7 t. f2 }8 Q2 T" @( Z
Lu X, Kang Y.8 u0 a- R c/ L" _( q: ^5 m7 T
SourceDepartment of Molecular Biology, Princeton University, Princeton, NJ, 08544, USA. Xin_Lu1@DFCI.HARVARD.EDU ( k' t/ N: n$ t6 ?& A 3 O; D$ r+ ?' z GAbstract% ~ D- z( d5 z7 p
A major advance in recent cancer research is the identification of tumor cells with stem cell-like properties. Cancer stem cells (CSCs) often represent a rare population in the tumor mass and possess the exclusive ability to initiate the growth of a heterogeneous tumor. The origin of CSCs remains elusive and is likely to be cancer type specific. One possible but under-appreciated potential mechanism for the generation of CSCs is through fusion between stem cells and differentiated cells. The cell fusion hypothesis of CSCs adds an important functional underpinning to the potential multifaceted roles of cell fusion in the initiation and progression of cancer.7 ]+ b$ b1 u/ D B
! P2 ]% F0 l: N& z 作者: subenjinwo 时间: 2012-2-26 16:16