从权威杂志blood, cancer research, cancer cell, cell, cell research, cell stem cell, development, gastroenterology, hepatology, journal of clinical oncology, journal of experimental medicine, journal of national cancer institution, JAMA, nature cell biology共收集研究性论文74篇,与大家分享。. |1 S; l" T( G+ I$ q
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& x* F" o+ M3 }- Q( `Chen, Y. 2011 A tumor suppressor function of the Msr1 gene in leukemia stem cells of chronic myeloid leukemia.9 i8 j6 i8 J: |, a5 t6 V
Blood # m$ F; W% g/ q, g添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012- J, \7 d; w! H F* ?8 c8 N
在线链接 转到 URL * J0 z+ W1 l7 \ 5 p, {5 o8 g5 EChomel, J. C. 2011 Leukemic stem cell persistence in chronic myeloid leukemia patients with sustained undetectable molecular residual disease.2 i5 r& V8 o) @0 S$ O% \
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6 n2 L+ W. K! h- [Chu, S. 2011 Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment. # L3 b* D- I, \8 U7 B$ TBlood & J. L0 p d- t0 K添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012; W& v* B# t$ n! r! C
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Jakubikova, J. 2011 Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications.3 A6 g) I% i3 @" N0 _$ B
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Risue漀, R. M. 2011 Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease. % q9 X+ ~; |3 q& ^ _, R% cBlood7 j' k5 k' n% Y8 p# G8 W6 d
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Tang, M. 2011 Dynamics of chronic myeloid leukemia response to long-term targeted therapy reveal treatment effects on leukemic stem cells. ( [( \$ L1 }0 J, | B% n) IBlood % w' q$ N3 b0 Y9 _0 m添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 9 l B) U# o0 x6 v8 X在线链接 转到 URL0 @3 d2 ~0 ]5 W p
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Tatarek, J. 2011 Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.7 A3 G* J) U7 ~5 l. S6 o
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添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 ! z- x" |0 ~1 A' B在线链接 转到 URL 3 Q& Z- K3 N6 a# u% d8 ` ) E3 n- _7 o! {4 F8 a _Chang, C. J. 2011 EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling.8 a2 A8 N, T- f4 a7 I6 Y9 x
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Goardon, N. 2011 Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia. " x1 Q8 w4 e. X4 jCancer Cell 8 M Y+ q1 t# t/ A. K添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012/ L7 s% A6 w+ ^) N
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3 T* M t* [) w# S! rGuryanova, O. A. 2011 Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. 5 x$ \4 Z; Z F% Q }$ sCancer Cell ( W. d; F# |4 N l; e添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012) z" o c! U2 b6 w. p; Z4 r8 [: l
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Lang, J. Y. 2011 BikDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment.( A8 }) _- U! a7 ] H$ g
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! B: O8 @+ L% v! k3 JArzumanyan, A. 2011 Does the hepatitis B antigen HBx promote the appearance of liver cancer stem cells? 5 \) C( q# j4 b9 Z* ICancer Res : G |; C# L' n6 V8 O添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 2 P2 q- X+ Y1 \: @; Z1 b在线链接 转到 URL9 H+ G9 P- c7 I9 k
7 i& J9 c6 _. c: d% s2 Z: FAsiedu, M. K. 2011 TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype.3 w d6 _) ?/ `" \5 z
Cancer Res; ?3 ~/ }6 c3 X
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% u2 J w l3 G2 O- X/ x! l; FBiddle, A. 2011 Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative. % E; K, X; c, x( m3 v( u/ kCancer Res% g; Y; _0 p! o( _2 L
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- k4 x! r: |2 x; d( b7 eCivenni, G. 2011 Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth.1 F- f/ s" k# L, V- J& T
Cancer Res * w* k h) A: B6 e6 u添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 2 s: N+ u( m$ E; ?2 K在线链接 转到 URL$ |' ], e1 N0 L/ b3 I
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Cui, X. 2011 Effects of carbon ion beam on putative colon cancer stem cells and its comparison with X-rays. 0 s5 J) q. X% N, u" Q% {Cancer Res & a- K3 | T9 s8 T7 [9 L5 D添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 20121 l. K# _) G! E/ P1 A
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Damelin, M. 2011 Delineation of a cellular hierarchy in lung cancer reveals an oncofetal antigen expressed on tumor-initiating cells. # G: ^, k: r6 R( x: h$ g8 j, a4 n4 VCancer Res- ]" F; }9 I+ n, C2 A4 ?
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在线链接 转到 URL 5 N# x4 O" i1 v W$ a0 ~& V' ]' QDotto, G. P. 2011 Calcineurin signaling as a negative determinant of keratinocyte cancer stem cell potential and carcinogenesis. 2 q% J: u$ c6 J9 ^4 T% y' vCancer Res/ H3 K) y2 X1 l [3 W
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Fischer, M. 2011 Anti-DLL4 inhibits growth and reduces tumor-initiating cell frequency in colorectal tumors with oncogenic KRAS mutations.& {+ Y$ E2 g! N) s" W
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3 h: l1 @ M- _Frank, N. Y. 2011 VEGFR-1 expressed by malignant melanoma-initiating cells is required for tumor growth.- k+ ~2 w. @, [( l! p( _
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Grange, C. 2011 Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche.- g, |7 Y3 z/ G7 q
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在线链接 转到 URL . L K$ [; t0 ?) N1 _ & S$ X) t C- e0 tGrinshtein, N. 2011 Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells.& o5 F8 o# i$ W6 }
Cancer Res$ t- E l) @ j X
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Jeon, H. M. 2011 ID4 imparts chemoresistance and cancer stemness to glioma cells by derepressing miR-9*-mediated suppression of SOX2. 2 s) j7 w5 _! o" cCancer Res & `8 c& H2 b3 a# U$ @0 q: t添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 2 V8 a& { C) H: Q, { f在线链接 转到 URL% r" L6 w0 r1 D- J1 O
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Liu, S. 2011 Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks.4 N" \/ |( w. c# D
Cancer Res . B3 E7 _- t* D- T& k& _, s添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 1 b: s0 {; I$ @4 F3 H% R- A! h* _1 r在线链接 转到 URL 8 k E3 i4 |/ L5 _2 Y4 Q 5 F. Z( _$ K( e9 Z* O% U9 TLo, J. F. 2011 The epithelial-mesenchymal transition mediator S100A4 maintains cancer-initiating cells in head and neck cancers. & W" i( G* @$ @" q3 i' LCancer Res , B! t8 b) I' c添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 20122 x3 j$ L7 x8 w, g8 h
在线链接 转到 URL : |9 o# o* R3 F * a, s: k7 I3 l# [. v1 v+ [Muraguchi, T. 2011 NKX2.2 suppresses self-renewal of glioma-initiating cells. $ V8 u& v$ {0 a0 O' S2 OCancer Res , y& e3 U: ?" k, W0 d添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012/ R( |# v7 X2 N. { v
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Silva, I. A. 2011 Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival. 1 b$ a4 s2 G. G( E9 @Cancer Res $ d# v8 A) _2 K5 b Q) j$ D添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012" {# n5 \: m& Z$ k4 C1 j/ g% q
在线链接 转到 URL / _, s& j6 B% @+ I 0 `' m }4 `( v) kTeng, I. W. 2011 Targeted methylation of two tumor suppressor genes is sufficient to transform mesenchymal stem cells into cancer stem/initiating cells.5 X" A% |+ A" X# G: O+ F
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! c0 W# k/ e6 k( j# |0 l1 tCordenonsi, M. 2011 The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. / H& C7 z/ ^( R w1 mCell 9 J9 V2 L# c9 v- R" {/ r4 w" D3 O; S; p添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 1 U1 } u; l' B- K6 ?在线链接 转到 URL: `/ \' X3 y6 ~9 F5 Q
$ l/ c4 ]0 m) n7 L8 REyler, C. E. 2011 Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. 8 r9 t* V v6 B& h" gCell " ?6 g# }$ w4 u0 j. k' M添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012! p+ i3 _+ `& |; u
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Gupta, P. B. 2011 Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells.8 b$ F+ q8 X. m- ]" L# N. y) V( B
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; D q- g+ `, L! S! W3 U0 tWilliams, S. A. 2011 USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma. , m3 x, M9 a- m/ f; W; GCell, O3 T( N# e+ {' I( U, a7 A$ E
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1 ~& s, y- P. s; n: L7 X4 rPezzolo, A. 2011 Oct-4+/Tenascin C+ neuroblastoma cells serve as progenitors of tumor-derived endothelial cells.( q: J! C2 C1 N1 _2 m
Cell Res 9 |1 T" z# i$ B$ M添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 1 |' m- i# C* U$ {* M* Z在线链接 转到 URL+ j. t* V' S4 N
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Lee, T. K. 2011 CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation.( m& B6 [- H; [
Cell Stem Cell 7 ~) x, R( s4 P2 C# l添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 ; ~4 h8 R" g9 B" w! H+ W3 K* W$ P在线链接 转到 URL - _) ~/ j. {: Q2 w* ?5 V x [" g7 m% Q6 P9 K! g; ~Merlos-Suárez, A. 2011 The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse.& C( O7 L- n% ? \. i; z
Cell Stem Cell ' e% P h: F0 H1 Q/ H5 b添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012) U+ c2 r _/ T# F, o _4 E
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Smith, L. L. 2011 Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells. , b" X2 H: J TCell Stem Cell ( K9 G+ ?$ V" B/ t* q4 T: b. ]添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 20129 h7 Q% l! a6 C
在线链接 转到 URL 3 ]8 ?$ Z% r Z) ]( V( p& v9 I 6 h% ?, K7 ^9 `' V; E- TWang, Y. 2011 Targeting HIF1α eliminates cancer stem cells in hematological malignancies.. G+ o% }, K4 O
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! e. O! C9 z& o5 n$ l5 l' MMillane, R. C. 2011 Induced stem cell neoplasia in a cnidarian by ectopic expression of a POU domain transcription factor. " n# N) r" ]% P; C$ o! m3 O. Z# [+ ZDevelopment; c& F- Y1 }. m- j
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Emmink, B. L. 2011 Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan. ! b( h+ C9 K, J- a5 }4 m' `& ?Gastroenterology. i" A9 |1 X* H3 p5 [1 R4 q# E% B
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Gaur, P. 2011 Identification of cancer stem cells in human gastrointestinal carcinoid and neuroendocrine tumors. 2 [% z t" w( `6 pGastroenterology G! p, N1 C: u: k
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Hwang, W. L. 2011 SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells.; G! k2 v. ]& G
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Li, C. 2011 c-Met is a marker of pancreatic cancer stem cells and therapeutic target.2 h8 J2 `! z# p. l) c
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Lombardo, Y. 2011 Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.; X! }% ^4 l4 @. ~9 o- t
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Woo, H. G. 2011 Association of TP53 mutations with stem cell-like gene expression and survival of patients with hepatocellular carcinoma. + {) E, T0 M* K# ^( T6 U' bGastroenterology H1 l9 L# G0 d$ H
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You, H. 2011 c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma. $ M( D% d) d, W# j: oHepatology" s w, A* n8 k+ Q/ p" u' b4 o' F
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) M8 z. X* z, s2 A- [# wHurtz, C. 2011 BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia. 7 z+ f4 ~1 I8 s6 a3 ?, pJ Exp Med ! @& i( u0 F2 j5 S添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 ) F8 c0 I7 K I在线链接 转到 URL " b1 i; L9 S4 y) J! G: N8 P7 E9 E1 {$ U* z. I/ T! W% [/ q9 j
Azzi, S. 2011 Differentiation therapy: targeting human renal cancer stem cells with interleukin 15. $ z w% m7 x- t4 j/ m' H. b" W/ dJ Natl Cancer Inst * p" B+ \1 m4 L( y' `0 t添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 4 ^" o0 M$ R/ Z在线链接 转到 URL ! M" a6 O. E K- ]! `% |+ ?4 }/ q) v / c) W8 n. S) L. H0 n" Y4 u, B8 Z$ PMasuda, S. 2011 Leukemic stem cell gene expression signature and clinical outcomes in acute myeloid leukemia. / ~5 d! T# `, b9 |1 HJAMA 2 R) s0 f& X( G添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012" I* w" s4 {& ^8 |# O
在线链接 转到 URL & M3 a }% k+ J ' ~$ c4 l) z jScaffidi, P. 2011 In vitro generation of human cells with cancer stem cell properties./ G* B& N6 [% V7 u' I' @3 z: Q
Nat Cell Biol8 Z7 S& [2 H, X8 Q. d5 @& c
添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 . ^) v2 V- e& e- _在线链接 转到 URL作者: csc1981 时间: 2012-3-4 19:57
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Eppert, K. 2011 Stem cell gene expression programs influence clinical outcome in human leukemia. $ f- R- [8 w8 _5 q$ d: SNat Med; }6 u' \2 Q0 t4 h" B$ `. O
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Liu, C. 2011 The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. ( K) S+ T( I# e' rNat Med ' n6 L8 a2 B8 @, }& \; M添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 $ a% s2 u7 z7 H% G6 W9 O) y在线链接 转到 URL ) |& ]/ e6 P m- Q9 g$ U ; d* E: h- a( M! X$ G+ a) w& EBeck, B. 2011 A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours.7 L5 z( v, L4 E7 e4 q4 D& C% Q
Nature 2 D; ?+ L- H9 W: d4 N# G, h添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 # ~' g# @! w$ Z, H& W( k在线链接 转到 URL * d5 F. R( \4 y ) K; s! o1 Y1 r9 p6 f# U- p( cCamper, S. A. 2011 Beta-catenin stimulates pituitary stem cells to form aggressive tumors. % h: b6 S8 y* v9 `1 h1 \% _* LProc Natl Acad Sci U S A 6 B: I: ^; ~. N) i- Y, p, E# k添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 \& G' A4 V" f$ T" y7 c
在线链接 转到 URL 8 N+ Y9 L9 X. a8 B4 Q 6 ?5 B8 K$ x9 |1 _9 w1 r4 sChaffer, C. L. 2011 Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state.1 l. D ~" ]5 O5 R
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Eliazer, S. 2011 Loss of lysine-specific demethylase 1 nonautonomously causes stem cell tumors in the Drosophila ovary. * h( |: R- |6 n4 c6 P' |Proc Natl Acad Sci U S A: t3 A) c# P% ~) x. w
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在线链接 转到 URL 1 w* S& j" b0 Y% f V! b1 d& Q ) I3 z3 v0 V5 qIliopoulos, D. 2011 Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion.9 u) C0 `5 T5 N3 R( i. j3 g7 I0 W
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Jan, M. 2011 Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker.& w9 u+ A: p4 W' v5 h& }$ Y0 D( \
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在线链接 转到 URL 3 I# E" G: i, A+ j 2 i; x- ?; C7 s7 _8 Y/ wJinushi, M. 2011 Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells. ; | H9 x: z1 o" G9 Y6 K# V% rProc Natl Acad Sci U S A ' o8 j1 o" H* F' [# m添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 # m+ X7 X0 v, L. Z4 q) g! a在线链接 转到 URL, k* e5 ~; A- i- o
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Li, Y. 2011 c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. 0 e5 @! Q! w# s6 ?- P: A4 ZProc Natl Acad Sci U S A- p( S. \. K/ _! p6 g u! G+ I
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m' g3 |$ F6 J9 MSchober, M. 2011 Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling. ( t9 c1 f) \$ B+ y8 Z6 |9 iProc Natl Acad Sci U S A9 {% M1 H' `! c6 {7 M: h( S
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Stewart, J. M. 2011 Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells. . [5 f, M3 n% |Proc Natl Acad Sci U S A- E U# T8 o( ^+ W& g) c
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在线链接 转到 URL 4 v# z+ Z, _" m : K4 U( G1 `# W6 l/ H- N. s; l4 n WVlashi, E. 2011 Metabolic state of glioma stem cells and nontumorigenic cells.5 ^8 g7 q; K4 k; w8 a
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Yeung, T. M. 2011 Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells.3 m9 z5 R2 B$ I8 X4 U4 s
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Broadley, K. W. 2011 Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme.4 N9 W8 f6 r! o5 G, w4 @ p
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Choijamts, B. 2011 CD133+ cancer stem cell-like cells derived from uterine carcinosarcoma (malignant mixed Müllerian tumor). 8 {" }$ T0 e G) zStem Cells - H w' n3 b; A- ^9 N% V添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012: c$ [! ~$ y( p9 g6 W4 o1 x
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Gallmeier, E. 2011 Inhibition of ataxia telangiectasia- and Rad3-related function abrogates the in vitro and in vivo tumorigenicity of human colon cancer cells through depletion of the CD133(+) tumor-initiating cell fraction. 3 h! x8 [; Z- \9 \. p" R y+ G9 H, xStem Cells 9 P+ s& m. n* p6 W5 Y6 s- z添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 2012 ; ^, D5 f$ v( P' ~" G& i; M在线链接 转到 URL' M; C" t5 j. V5 D2 N% u
, X7 \% j- w* z: g% N6 T7 ZHide, T. 2011 Combination of a ptgs2 inhibitor and an epidermal growth factor receptor-signaling inhibitor prevents tumorigenesis of oligodendrocyte lineage-derived glioma-initiating cells.1 N& g" n; H) G* Z% S! W j. e# T! S
Stem Cells $ h4 `; X8 j' k# D. A o* J添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 20122 p- K& ]3 E6 c5 a
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Marcato, P. 2011 Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis. & R4 C. N# A" y* [- eStem Cells6 v. R2 K) G, W$ n
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Silvestre, D. C. 2011 Alternative lengthening of telomeres in human glioma stem cells. 0 J# L3 ]( Y( k$ WStem Cells 4 v- j: y$ x$ l添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 20126 c, t+ @2 b# h3 J; J' u
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Sunayama, J. 2011 FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity. 0 v! O6 e7 y' RStem Cells( _! N& w/ f8 N8 \9 R) G
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0 y4 _; c9 E' z5 P# S8 C# }9 i( i( UToivanen, R. 2011 Brief report: a bioassay to identify primary human prostate cancer repopulating cells. 8 E7 [: v7 L' O; E+ ^Stem Cells ) p$ l2 O( j0 H4 v* f4 l添加到文献库: 03 Mar 2012上次更新日期: 03 Mar 20128 c7 p# ]1 S6 k ]+ ^# t
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% c8 J" y" e: U" vYing, M. 2011 Krüppel-like family of transcription factor 9, a differentiation-associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells. 7 G: q6 }1 T6 v+ r, n3 c/ u1 kStem Cells j: u& X* ^% C
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在线链接 转到 URL作者: xiongjiedeng 时间: 2012-3-4 23:40