本帖最后由 细胞海洋 于 2012-4-2 08:50 编辑 ; i z4 M( [2 y% o- {6 B
, V9 `6 O: q4 J" V& \8 F, N; l7 t . t' _" ]) x% m: j. y! V% }Volume 19, Issue 3 - y! Q$ }$ W2 K& {# VOn the cover: Fluorescent proteins are power tools for cell biology. The 6 ~8 r( s1 \5 z# \+ U/ e0 i" I9 D
current challenges in the field include designing bright dimeric red fluorescent 7 d, P+ I. M5 q2 g$ ^4 o8 r( `1 Q8 Q7 Sproteins active in live cells. In this issue, Alford et al. (pp. 353–360) ! Q7 X* `# }- t! \( D* Gdescribe the development of such a system, a dimerization-dependent red : J& L& p2 |" ?+ x
fluorescent protein, or ddRFP, comprised of non- or dim-fluorescent protein . N0 C% b: e$ s- _) ?6 rmonomers. On the cover, streams of colorless solution pour from two distinct + s& m- ~* a1 Z
monomers, symbolizing non- or dim-fluorescent entities. As the solutions pool J, j# b- n$ L( C; N; n+ i ^and mix, a red color develops, representative of the fluorogenic signal - ^8 c2 D1 f6 D2 Fgenerated upon heterodimer formation. The structure in the foreground is the 3 L- e2 q. d5 }& }source of the red color: the complete ddRFP. Image created by Michael W. / H' |$ `( \7 q# N% nDavidson, Spencer C. Alford, and Robert E. Campbell. 5 `, q% Q' R" Y" Z# m. a# @$ J ( m7 x+ @' x- c* K' h! i作者: zorro 时间: 2012-4-2 09:39
3qqq作者: lgclgc 时间: 2012-4-4 17:59
very good, thank you作者: haibara007007 时间: 2012-4-5 22:58
