! R5 [; b2 C/ i. nWashington, Sept. 4 (ANI): Researchers have discovered a method to resynchronize cardiac motion following a heart attack with the help of stem cells.0 ~+ ^, t( l5 {8 ~* y2 l; I+ e, @: F6 \/ Y
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Scientists implanted engineered stem cells, also known as induced pluripotent stem (iPS) cells, into damaged regions of mouse hearts following a heart attack. This regenerative approach successfully targeted the origin of abnormal cardiac motion, preventing heart failure. & A8 x4 Y- x% y/ D k7 W, ^8 P! G d4 I
Andre Terzic, M.D., Ph.D., senior author of the study, said that the discovery introduces - for the first time - stem cell-based 'biological resynchronization' as a novel means to treat cardiac dyssynchrony.- d/ X$ t) _4 d; ]# Z! o- g+ e7 ?
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Muscle damage following a heart attack may disrupt normal heart conduction, resulting in a condition known as cardiac dyssynchrony. ' Q }+ O/ G3 K7 U) j, R- e+ s" o) X, l. Z ^
Stem cell-based repair is going to offer a new solution to patients who would otherwise be resistant to device-based resynchronization. ( V- E2 x1 x0 `7 ]: k7 X" Y 8 v4 U/ S: ]* A3 X0 D5 D+ uSatsuki Yamada, M.D., Ph.D., first author of the study, said that a high-resolution ultrasound revealed harmonized pumping where iPS cells were introduced to the previously damaged heart tissue. ( ?- |, s6 u3 Y) K' q+ I 1 y6 y, y7 s% _9 ?1 RThe study provides evidence that a stem cell-based intervention may be effective in synchronizing failing hearts. Additional studies will follow to validate the value of stem cell-based regenerative solutions in addressing abnormal cardiac motion in heart failure, ultimately leading to improved patient care. ! g; D4 ]; ]5 O/ J7 ?; r! R # J s! V- ?! H% iThe findings have been published in the Journal of Physiology. (ANI)作者: yuanshenyewu 时间: 2013-9-12 20:03