+ f. i. m7 ?- v4 X O( O6 L* g& G ; m* k ^* Y! w/ L$ T1 \5 December, 2013 Volume 155, Issue 6 8 k9 H7 F; i( C3 m/ ^On the cover: The nuclear pore complex ; F- T* {6 `: R! ?
(NPC) is a large multisubunit structure that regulates the exchange of - e8 _; h( [9 s/ ]2 {4 c
macromolecules between the nucleus and the cytoplasm. In this issue, Huy et al. ) U/ K) S2 v: Q7 S! m4 d# A
(pp. 1233–1243) use an integrated approach to establish the blueprint for the 0 D7 G; _8 \ Y& Bstructure of the NPC scaffold in humans and explain how changes in the diameter : E" V2 r c) ?1 ^) ]
of this scaffold enable the transport of large cargoes. Cover artwork by Khanh 4 J) p# X4 a8 r4 N; A, P3 z! jHuy Bui. Original photo by Alan Levine. - L' ]- { U1 k8 F/ D9 X9 d* J) z" m- i
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