2013年12月5日 Cell * U0 O( U+ ?6 m9 ~; g( ]. i3 `5 i) [, o* s/ g1 x 3 Q( n, R+ n& Q. a5 `! j
5 December, 2013 Volume 155, Issue 6 $ R9 d( r8 W$ FOn the cover: The nuclear pore complex * x/ Q2 k/ W0 S. }; L" N* n(NPC) is a large multisubunit structure that regulates the exchange of 2 ?2 |/ R% d+ }# h0 Amacromolecules between the nucleus and the cytoplasm. In this issue, Huy et al. , @" @6 K3 ?' {3 H* u- n9 f(pp. 1233–1243) use an integrated approach to establish the blueprint for the $ J8 ~+ f8 `5 v6 ^) G/ dstructure of the NPC scaffold in humans and explain how changes in the diameter 1 ^2 ], b8 @8 ~) u3 C& u- T K
of this scaffold enable the transport of large cargoes. Cover artwork by Khanh # }/ H/ z( ], e- T0 n/ NHuy Bui. Original photo by Alan Levine.* j. x! b6 L+ {- x' q0 }
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1 m5 }2 D2 | ^ 作者: loyal 时间: 2014-1-2 09:33
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