最近在论文中看到下面一段话，不能理解，为什么间充质细胞具有免疫抑制能力就会对受损神经的修复有好处， 求解答。 - e* f* a Y# j: \ Q# L( tRecent studies have suggested that the immunomodulatory activity of MSCs is of crucial # y$ w4 ?$ w+ c' kimportance to cell therapy using MSCs. There is in vitroevidence that MSCs can directly modulate the function of T-cells. Moreover, they inhibit the maturation and migration of various antigen-presenting cells, suppress B-cell activation, induce suppressor T-cell formation, and alter the expression of several receptors necessary for antigen capture and processing9 e5 X% G* B* a. p" o$ c: l6 ]
. This immunosuppressive activity of MSCs may play an important role in the repair of nervous system injuries.作者: jxydiandian 时间: 2014-3-1 08:52
Could you provide the information after this sentence? I think the author should mention something concerning the point. BTW, jxydiandian's comment might also play an key role to prevent immunoloical attacks after the nervous injury. But I son't know how to have a function on repair. 作者: zjj196512 时间: 2014-3-19 10:34
mscs may increse some cotekines that have trophic effecton to nerve.作者: lordstar 时间: 2014-3-19 10:45