2015年浙江大学干细胞与再生医学研究中心研究成果(截至2015-11-30)

林辉

发表文章22篇，其中影响因子大于5分的15篇
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1．Li QB, Tang Q, Zhang PZ, Wang ZH, Zhao TT, Zhou JL,Li HR, Ding Q,Li W, Hu FQ, Du YZ, Ruan H, Chen SQ, Gao JQ, Zhan JB*, You J*. Human epidermal growth factor receptor-2 antibodies enhance the specificity and anticancer activity of light-sensitive doxorubicin-labeled liposomes. Biomaterials 2015, 57: 1-11. (IF 8.31)4 r8 n$ A# P1 x9 ~

' |( k# w2 F. X. g5 A7 F2．Huang YT, Zhou J, Shi S, Xu HY, Qu F, Zhang D, Chen YD, Yang J, Huang HF, Sheng JZ*. Identification of Estrogen Response Element in Aquaporin-3 Gene that Mediates Estrogen-induced Cell Migration and Invasion in Estrogen Receptor-positive Breast Cancer. Scientific reports. 2015 Jul 29;5:12484. (IF 5.578) - L# L) u: ^% F+ |0 N0 r" B* E, K
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3．Zhu S, Dai J, Liu H, Cong X, Chen Y, Wu Y, Hu H, Heng BC, Ouyang HW*, Zhou Y*. Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development. Arthritis Rheumatol. 2015 May;67(8):2154-63. (IF7.871)
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- O5 o0 w. L' e$ K% e& `1 m. y4．Pan YB, Gong Y, Ruan HF, Pan LY, Wu XK, Tang C, Wang CJ, Zhu HB, Zhang ZM, Tang LF, Zou CC, Wang HB, Wu XM*. Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth. Cell Death Dis. 2015 Feb 19;6:e1653. (IF 5.014)
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5．Yao H, Shi W, Wu J, Xu C, Wang J, Shao Y, Wu X*, Zhang Z*. Endothelial Rac1 is essential for hematogenous metastasis to the lung. Oncotarget. 2015 Jul 10;6(19):17501-13. (IF 6.359)& p6 [. z; B& {+ o% B" {5 J: x$ I# [
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6．Quan Wang, Qingqing Xia, Yan Wu, Xiaolei Zhang, Feiqiu Wen, Xiaowen Chen, Shufang Zhang, Boon Chin Heng, Yong He and Hong-Wei Ouyang*. 3D-Printed Atsttrin-Incorporated Alginate/Hydroxyapatite Scaffold Promotes Bone Defect Regeneration with TNF/TNFR Signaling Involvement. Adv Healthc Mater. 2015 Aug;4(11):1701-8. (IF 5.797)
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. p- y/ h, N: F+ Z) q( W2 d7．Wang J, Wang J, Lu P, Cai Y, Wang Y, Hong L, Ren H, Heng BC, Liu H, Zhou J*, Ouyang H. Local delivery of FTY720 in PCL membrane improves SCI functional recovery by reducing reactive astrogliosis. Biomaterials. 2015 Sep;62:76-87. (IF 8.557) 6 u) l3 N$ X' o' K. Q
8．Zhang C, Yuan H, Liu H, Chen X, Lu P, Zhu T, Yang L, Yin Z, Heng BC, Zhang Y, Ouyang H*. Well-aligned chitosan-based ultrafine fibers committed teno-lineage differentiation of human induced pluripotent stem cells for Achilles tendon regeneration. Biomaterials. 2015 Jun;53:716-30. (IF 8.557) 9 X7 t$ _! q6 V  \/ z5 K, @
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9．Xia Q, Zhu S, Wu Y, Wang J, Cai Y, Chen P, Li J, Heng BC, Ouyang HW*, Lu P*. Intra-Articular Transplantation of Atsttrin-Transduced Mesenchymal Stem Cells Ameliorate Osteoarthritis Development. Stem Cells Transl Med. 2015 May;4(5):523-31. (IF 5.709)
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10．Chen X, Gu S, Chen BF, Shen WL, Yin Z, Xu GW, Hu JJ, Zhu T, Li G, Wan C, Ouyang HW, Lee TL, Chan WY. Nanoparticle delivery of stable miR-199a-5p agomir improves the osteogenesis of human mesenchymal stem cells via the HIF1a pathway. Biomaterials. 2015 Jun;53:239-50. (IF 8.557)
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11．Yin Z, Chen X, Song HX, Hu JJ, Tang QM, Zhu T, Shen WL, Chen JL, Liu H, Heng BC, Ouyang HW*. Electrospun scaffolds for multiple tissues regeneration in vivo through topography dependent induction of lineage specific differentiation. Biomaterials. 2015 Mar;44:173-85. (IF 8.557)
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/ ~; i, r8 z$ }4 L2 F7 H12．Chen P, Tao J, Zhu S, Cai Y, Mao Q, Yu D, Dai J, Ouyang H*. Radially oriented collagen scaffold with SDF-1 promotes osteochondral repair by facilitating cell homing. Biomaterials. 2015 Jan;39:114-23. (IF 8.557)
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13．Zhu S, Lu P, Liu H, Chen P, Wu Y, Wang Y, Sun H, Zhang X, Xia Q, Heng BC, Zhou Y, Ouyang HW*. Inhibition of Rac1 activity by controlled release of NSC23766 from chitosan microspheres effectively ameliorates osteoarthritis development in vivo. Ann Rheum Dis. 2015 ;74(1):285-93. (IF 10.377)0 |2 e, e. }" G3 \, b0 h* ?4 a( N* K% u

; w4 Z  q( K" f4 v, L! A  v( ]9 Y14．Liu H, Zhang C, Zhu S, Lu P, Zhu T, Gong X, Zhang Z, Hu J, Yin Z, Chin Heng B, Chen X,  Ouyang HW*. Mohawk Promotes the Tenogenesis of Mesenchymal Stem Cells through Activation of the TGFβ Signaling Pathway. Stem Cells. 2015 Feb;33(2):443-55. (IF 6.523)' O. u9 T- g# i, M
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15．Qi S, Fang Z, Wang D, Menendez P, Yao K, Ji J*. Concise review: induced pluripotency by defined factors: prey of oxidative stress. Stem Cells. 2015 May;33(5):1371-6. (IF 6.523)
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16．Zhou Q, Xu C, Cheng X, Liu Y, Yue M, Hu M, Luo D, Niu Y, Ouyang H, Ji J, Hu H*. Platelets promote cartilage repair and chondrocyte proliferation via ADP in a rodent model of osteoarthritis. Platelets 2015, Sep 1:1-11. (IF 2.982)
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17．Yi P, Chew LL, Zhang Z, Ren H, Wang F, Cong X, Zheng L, Luo Y, Ouyang H, Low BC, Zhou YT*. KIF5B transports BNIP-2 to regulate p38 Mitogen-Activated Protein Kinase activation and myoblast differentiation.  Molecular Biology of the Cell 2015 Jan 1;26(1):29-42. (IF 4.466)6 `6 i2 D- V( l- E
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18．Zheng LL, Wang FY, Cong XX, Shen Y, Rao XS, Huang DS, Fan W, Yi P, Wang XB, Zheng L, Zhou YT*, Luo Y* (2015),  Interaction of heat shock protein Cpn10 with Cyclin ECdk2 substrate NPAT is involved in regulating histone transcription. Journal of Biological Chemistry, doi: 10.1074/jbc.M115.659201. (IF 4.573)$ G; w; i9 u8 o; u2 U
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19．Tang C, Pan Y, Luo H, Xiong W, Zhu H, Ruan H, Wang J, Zou C, Tang L, Iguchi T, Long F, Wu X*. Hedgehog signaling stimulates the conversion of cholesterol to steroids. Cell Signal. 2015 Mar;27(3):487-97. (IF 4.315)
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20．Tang C, Mei L, Pan L, Xiong W, Zhu H, Ruan H, Zou C, Tang L, Iguchi T, Wu X*. Hedgehog signaling through GLI1 and GLI2 is required for epithelial–mesenchymal transition in human trophoblasts. Biochim Biophys Acta- General Subjects. 2015 Jul;1850(7):1438-48. (IF 4.381)2 ^( P/ r1 ]6 e" P1 F  P, b

4 n) [. v# P0 V( e6 H1 T( z2 A21．Wu Y, Jing D, Ouyang H, Li L, Zhai M, Li Y, Bi L, Guoxian P. Pre-implanted Sensory Nerve Could Enhance the Neurotization in Tissue-Engineered Bone Graft. Tissue Eng Part A. 2015 Aug;21(15-16):2241-9. (IF4.697)
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2 `5 f% M% Z$ S/ F22．Chen JL, Zhang W, Liu ZY, Heng BC, Ouyang HW, Dai XS. Physical regulation of stem cells differentiation into teno-lineage: current strategies and future direction. Cell Tissue Res. 2015 May;360(2):195-207. (IF 3.565)5 A" n& D) y  G4 G8 ~

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