PDF电子书：Transgenic Mouse Methods and Protocols

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6 t: F$ O# M2 V, _, x( ^% B. qTransgenic Mouse Methods and Protocols# y+ i( p1 V& f+ S- X! ?# G8 h
Authors: Hofker, Marten H. (University of Maastricht, Maastricht, The Netherlands) van Deursen, Jan (Mayo Clinic, Rochester, MN)3 G, g0 R7 Z5 o6 c
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Publishing: Humana Press0 ?; |1 P8 t! R6 i6 j
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Published: 2002 August
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" [% h: d1 V2 N9 v0 B) w% OMarten Hofker and Jan van Deursen have assembled a multidisciplinary collection of readily reproducible methods for working with mice, and particularlyfor generating mouse models that will enable us to better understand gene function. Described in step-by-step detail by highly experienced investigators, these proven techniques include new methods for conditional, induced knockout, and transgenic mice, as well as for working with mice in such important research areas as immunology, cancer, and atherosclerosis. Such alternative strategies as random mutagenesis and viral gene transduction for studying gene function in the mouse are also presented. 4 o% ]5 U' _  D: C4 @
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