News from ISSCR- The Pulse e-newsletter for Dec. 2009

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The Pulse% Y7 z4 O) S; j
The ISSCR Newsletter
% {/ y, X5 K/ a, r9 EVolume 8, No. 12
; a$ N; v, E/ S! |3 IDecember 20098 `8 \2 y; v" Z7 v
In This Issue:
8 {4 A0 R, @; j1 J9 C" Z4 uEditor's Message
7 B0 I5 U) `2 ~- q) dISSCR 8th Annual Meeting # T- @) }0 p- t- x! g* V/ ]6 E4 a7 B
News Roundup
# S' Q6 G9 n8 Z4 WJob Opportunities
6 y% f) V  O" j3 G' U4 uFunding and Award Opportunities
. ?1 {) L0 a* j( a9 {! r' _Meetings and Courses
' l1 M. L$ u! S0 G% RLiterature Highlights
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2 G7 a- R- Y3 \! ^' y1. Editor's Message
; M% F, h8 q0 x7 ?4 x6 B* mHeather Rooke, PhD
2 ?# s* \0 I8 }+ c% a/ o3 Rhrooke@isscr.org6 r) e2 \) q; F+ e" H
ISSCR 8th Annual Meeting, San Francisco, CA USA, June 16-19, 2010, co-sponsored by the California Institute for Regenerative Medicine (CIRM). Plan now to join us in San Francisco for another spectacular meeting — program development is well underway with more than 50 speakers confirmed for the scientific sessions and a range of additional networking and educational events planned. Registration opens this month and abstract submissions are being accepted through Jan. 14, 2010. Look for more information in Section 2 of this newsletter and on the ISSCR Web site.; c% j% b  l3 X/ k
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NEW— Call for Proposals: Satellite Symposia at the ISSCR 8th Annual Meeting. The ISSCR will make limited space available for satellite symposia on the morning of Wednesday, June 16, preceding the start of the 8th Annual Meeting in San Francisco, CA, USA. The space is available for any non-profit organization with a connection to stem cell research who would be interested in organizing a symposium focused on a topic of interest to ISSCR attendees. In holding satellite symposia, the ISSCR’s goal is to increase the representation of topics at the annual meeting that are of interest to constituencies within the society, but which are difficult to adequately represent within the main scientific program. For more information, contact Michael Hagedorn, mhagedorn@isscr.org, +1-847-509-1944 ext. 211.% d; p; z9 s: [; E- K4 g5 ?
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Second Annual ISSCR Outstanding Young Investigator Award. Draw attention to an exceptional young scientist you know. Members are invited to nominate young scientists who have demonstrated exceptional achievement in the field of stem cell research for this prestigious award, supported by the University of Pittsburgh. The winner will be honored at the ISSCR 8th Annual Meeting in San Francisco, CA, USA. Submissions accepted through Feb. 26, 2010. Read more.# G& e. M- {5 S8 k" [1 X
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Educational video competition. Create an original video that educates the public about stem cell science and earn a chance to win three complimentary associate member (junior investigator) registrations to the ISSCR 8th Annual Meeting in June, 2010. Submissions accepted through Feb. 26, 2010. Learn more. & Q$ N( E9 ~& Z: \, i9 Q
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Society for Biological Engineering’s (SBE) Second International Conference on Stem Cell Engineering, May 2-5, 2010, Boston, MA USA. Cosponsored by the ISSCR, this conference will bring together the bioengineering and stem cell biology communities emphasizing how basic and applied efforts in stem cell biology and engineering can combine to support the development of stem cell therapeutics and bioprocesses. Abstract submission deadline is Jan. 22, 2010. Learn more.
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+ y( ~% K9 U# C: r' ]" a3 [& G! lRecap: International Symposium on Stem Cell Research, Nov. 12-14, 2009, Buenos Aires, Argentina. Hugely successful, this ISSCR-affiliated conference showcased local research and development in the stem cell arena together with a range of international speakers and a focus on cardiologic and neurological diseases. Look for the upcoming meeting report to be published in the ISSCR pages of Cell Stem Cell. The conference also provided a forum for the signing of a five-year research cooperation agreement between Argentina and Brazil. Read more.
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2010 ISSCR Dues. The 2010 dues renewal notices have been sent to ISSCR members. Return the renewal invoice with the back side completed, or use our online system to renew your membership and update your member profile; simply log in to the members-only section and follow directions on the top left-hand side under member profile. You may pay for your membership for three years at a time, receiving a modest discount on the total. Reduced rates are available to associate members and members from certain developing countries. New this year: The ISSCR Board of Directors asks all members to provide demographic information regarding stem cell therapies along with their membership renewal. View membership information for 2010.
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+ m+ \. O! p# n6 nReach 11,000 — Sponsor The Pulse e-newsletter. Did you know each month an exclusive sponsorship is available for the ISSCR’s e-newsletter, The Pulse? This sponsorship puts your company in front of 11,000 stem cell researchers, clinicians, regulatory officials, industry representatives, government authorities and others with an interest in stem cell research. Contact Lisa Kamen to reserve space for select 2010 issues, or click here for more information." u. U6 W1 P6 i2 @
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2. ISSCR 8th Annual Meeting
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) `7 H; X7 d% z7 Q5 p; gISSCR 8th Annual Meeting" R, A$ r4 t9 [2 ?4 P0 V. x
June 16-19, 2010; D6 H; n5 k1 N* ?) q, |7 A' p8 J
San Francisco, CA USA
. ]1 d! J# Q7 YCo-sponsored by the California Institute for Regenerative Medicine (CIRM), V! ?' S: K" Z8 @7 E4 E6 E& ?7 @

+ |! V  l- A& y/ p/ BImportant Dates; y( ^4 V1 [1 }  c
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Abstract submission deadline: Jan. 14, 2010  
* e6 Z1 a: c! w% f: sRegistration begins: Dec. 2009 & S2 a- K% j, C7 m2 e

+ W* V; M4 f4 H3 S7 {0 FRegistration begins this month. Look for an e-mail alert that will be sent when registration starts and check the ISSCR Web site for details. Hear from some of the world’s top researchers speaking at the Annual Meeting, and view an expected 2,000 posters featuring the latest work in stem cell science. View the list of more than 50 confirmed speakers to date. A detailed program, including additional networking and educational events, will be available soon on the ISSCR Web site.
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, `- t! }! X: c; B; ]Submit an abstract today. Ensure your science is part of this unparalleled event. Just five weeks remain before the ISSCR Annual Meeting abstract submission deadline: Jan. 14, 2010. Abstracts are invited under any of 15 categories and may be considered for an oral presentation. Reminder: you will be required to select a secondary submission topic and also to provide keywords that best describe your research to allow efficient grouping of posters and a simpler way to find abstracts when on site at the meeting.
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0 H( M4 p, k  ^$ o: ZNew this year! In addition to those abstracts selected for oral presentation, select posters will be highlighted in a plenary session with a one-slide, two-minute ‘teaser’ from the contributing author.$ @# [" ?$ {+ K$ e: b: t

. h8 [" l; s/ o, ~The ISSCR has a non-refundable $50 USD abstract submission fee for each submitted abstract. ISSCR members were e-mailed their abstract submission account information on Oct. 13. Applying members or non-members must create a login account. Find answers to other frequently asked questions about the abstract submission process on the ISSCR Web site. If you have additional questions, contact Michael Hagedorn (mhagedorn@isscr.org; +1-847-509-1944).
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  E/ A7 i2 J+ n) F2 t4 JTravel Grants. The ISSCR will award grants to assist with travel to attend the 2010 annual meeting. Applicants must be current members and submit an abstract to be eligible for a travel grant. During abstract submission, check the appropriate box for travel grant application and provide a short paragraph (200 words maximum) explaining your economic need. All travel awardees must register for the annual meeting. Application deadline: Jan. 14, 2010.' e* Q. O+ t. Y

. S; S$ |3 L( @" W  m- S& bISSCR/CIRMWorkshop for 20106 p7 |+ a0 J6 a
Stem Cell Therapies in Clinical Trials - Best Practices and the Need for Harmonization. June 15, 2010, 8:30 a.m. - 5:30 p.m., Marriott Marquis San Francisco, CA USA
" C/ _* c6 L: {1 g8 _This interactive workshop preceding the ISSCR 8th Annual Meeting will provide a forum to examine the issues involved in harmonizing regulatory features internationally so that there are registered clinical trials conducted under common minimum standards accepted by global and national government regulators. It will be of interest to heads of Institutional Review Boards, Ministers of Health (MOH), researchers in industry and translational researchers, government regulators, and quality control and quality assurance staff. Registration information will be available on the ISSCR Web site. Registration will be limited.5 c& t5 ?! F8 U: r3 m' z! s% P

$ c9 \$ f! M% H$ j) [) ~$ }Spotlight on Junior Investigators. Dedicated events, including meet-the-experts lunches, a career panel and a social mixer are planned for junior investigators at the 2010 annual meeting in San Francisco. These offer prime opportunities for junior investigators to interact with top researchers in the field, as well as with each other in a unique and dynamic setting. Watch for the upcoming meeting program for details.
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Exhibit at or be a supporter of the ISSCR Annual Meeting. Visit the ISSCR Web site to view exhibit, support and marketing opportunities available for 2010.
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3. News Roundup
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Argentina-Brazil. The Ministry of Science, Technology and Productive Innovation of Argentina and the Ministry of Health, the Ministry of Education and the Ministry of Science and Technology of Brazil signed a five-year cooperation agreement during the International Symposium on Stem Cell Research, Nov. 12-14, 2009, in Buenos Aires. The agreement is intended to initiate a long-lasting cooperation between the two countries on stem cell research and includes financial support for joint research projects, human capacity building and the establishment of research facilities in the area of stem cells.
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! O1 Z, o5 c, a# R; ~2 U4 b) cIn photo: ISSCR Executive Director Nancy Witty and ISSCR President Irving L. Weissman at the International Symposium on Stem Cell Research, Nov. 12-14, 2009, in Buenos Aires, co-sponsored by the ISSCR.
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United Kingdom. The Human Tissue Authority's (HTA) revised Codes of Practice came into force on Sept. 15, 2009, following approval by Parliament in July 2009. The Codes of Practice provide guidance and lay down standards for each of the HTA's regulated sectors. Seven of the HTA's original eight Codes of Practice have been revised and a new Code of Practice for Research has been added. More information.
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California, USA. The California Institute for Regenerative Medicine, in partnership with the Medical Research Council (MRC), UK, and the Cancer Stem Cell Consortium (CSCC), Canada, awarded more than $250 million in Disease Team Research Awards to 14 multidisciplinary teams of researchers in California, the UK and Canada. The awards focus on the development of stem cell-based therapies and include strategies for 11 diseases. Approximately $8 million from the MRC, and approximately $35 million from the CSCC, help fund the international portions of the collaborations. Read more.5 d9 n9 O+ H. i/ F0 G

8 M6 f- k; [* Y& q& z- S  a8 l! HNIH, USA. On Dec. 2, 2009, the National Institutes of Health (NIH) announced the listing of 13 human embryonic stem cell (hESC) lines as eligible for use in NIH-funded research under guidelines adopted on July 7, 2009. The guidelines implement President Obama’s executive order of March 9, 2009, and establish policy and procedures under which the NIH will fund hESC research. Additional lines are expected to be posted in the NIH registry as they are reviewed and approved. More information.. C4 S7 a: J. E/ m' c* R

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4. Job Opportunities( o3 `8 B  r) S, a0 x

$ u# r, b! m+ h8 K1 `3 `Looking for a job? View the twelve new positions posted in the past month. Looking to hire? Use ISSCR's Job Bank to view resumes and jobs, and post positions in the stem cell industry. The Job Bank provides a targeted way to match available people and positions in stem cell research.% g$ z5 z) a+ U, u

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7 N* I! s2 W" |5. Funding and Award Opportunities
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Visit the Funding Corner of the ISSCR Web site for additional opportunities, more information or to plan ahead.% e1 l% n2 N) D6 z. g* p- D

5 [1 Q8 n* T  `/ f* MAlzheimer’s Research Trust, UK
. N7 U" G- z) b6 Q1 Q( ~$ hThe trust funds researchers in the UK working on all aspects of the translational pathway, including basic research, early detection, risk factor identification, alleviation and progress towards effective treatments in Alzheimer’s and related dementias. International collaborations with UK-based lead researchers considered. A range of opportunities have a deadline of Jan. 29, 2010, including several research fellowships (encompasses travel) and major project funding.
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New York Stem Cell Foundation (NYSCF)( [5 \. g; M$ ]* F& M

  j0 ?) ?5 {; kPost-Doctoral Research Fellowships ! a% Y  i- f: {' H2 S, Q- x
Application deadline: Jan. 15, 2010
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( I7 I1 i' O' A  i- F. tThe Royal Society
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JSPS Postdoctoral Fellowship Program
. O8 ^( G1 d0 t9 lApplication deadline: March 1, 2010
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Wellcome Trust, P/ N1 Z! _- h  g' D, ?
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Research Career Development Fellowships in Basic Biomedical Science
) H9 t  n" Y* z% u8 NNext preliminary application deadline: March 8, 2010* |* n4 v' @9 F" U. g; H' o7 S; [9 I
Invited full application deadline: May 24, 2010, e0 u$ p, M0 R/ {2 u$ @
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Boehringer Ingelheim Fonds1 w4 f/ z- w: ?1 ]+ p5 a4 O
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PhD Fellowships: Y7 ^! T. a" ^, [' ^
Application deadline: Feb. 1, 2010$ U" l: z9 s/ f- z/ }$ V( h( O8 Y

- M+ n% E; Z0 o1 KNational Science Foundation (NSF) % ]1 c+ T  }5 @3 B
This independent U.S. federal agency funds discovery, learning, research infrastructure and stewardship. Some relevant grants with upcoming deadlines include: : R4 l4 ]8 u! X  N. S

" \0 {. c7 r- X1 v2 A* UCellular Systems Cluster, Developmental Systems and Genes and Genome Systems Cluster
$ u* m) D! Q) E4 EApplication deadlines: Jan. 12 and July 12, 20105 ?! \8 a+ I% Q  J
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Science, Technology and Society  e' v: i5 n# l- S
Application deadlines: Feb. 1 and Aug. 1, 2010: x  g8 X. k7 d+ a6 n8 t4 C

( V5 g" B3 ~+ F  L- w7 q$ n4 g% zBiotechnology, Biochemical, and Biomass Engineering (BBBE)6 m) A) j* Q4 `( J/ v
Application deadlines: March 3 and Sept. 23, 2010
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, F& N6 U, N9 O) T/ [International Research and Education: Planning Visits and Workshops
0 g4 _0 S( d2 ^3 n6 D8 aApplication deadlines: Feb. 20, May 20, Sept. 20, 2010
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6. Meetings and Courses# F' \0 ~$ t: @- @
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The ISSCR lists many relevant stem cell meetings and courses. Included in this issue are meetings occurring or with deadlines that fall within the next one-to-two months. To view additional meetings and courses, visit the Meetings or the Stem Cell Courses pages of the ISSCR Web site. Click here to submit a meeting to be considered for possible inclusion on the ISSCR meetings calendar.4 z% t( p. M. V4 R/ _
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Upcoming Meetings:
4 v* j& \- ?. x1 j) q' IReprogramming Cell Fate Basic Biology and Medical Perspectives
8 K- H9 g+ N& U; d# x' gDec. 11 - Dec. 13, 2009 6 n! @. B+ T5 ^0 n
Milan, Italy
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. n$ Z. R$ }; Y' K  yStem Cells World Congress ( g. B$ G  i6 f) K
Jan. 20 - 21, 2010
) O) S5 O' O. d  {1 h' {+ ESouth San Francisco, CA USA 8 r  P9 R) J! `
In association with: World Biobanking Summit. V' b/ y" |* ?/ {3 K* G
Abstract submission deadline: Dec. 15, 2009
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Keystone Symposia - Stem Cell Differentiation and Dedifferentiation . d& V% }9 z" ?
Feb. 15 - 20, 2010 , }0 Q0 u0 i) d/ t: |
Keystone, CO USA 6 Q% b# {0 x0 ^
Discounted registration deadline: Dec. 15, 2009: k# x. _# t: m* g. r+ |; `; E
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Keystone Symposia - Cardiovascular Development and Repair
5 O' j3 n4 C2 J3 M# DFeb. 28 - March 5, 2010
+ I( A1 X4 z  ^( t0 `. jKeystone, CO USA
9 [6 e  `3 d0 vIn association with: Keystone Symposia - Angiogenesis in Health and Disease (held jointly)$ F" K2 K+ d# D4 z
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4th Biennial Heart Valve Biology and Tissue Engineering Meeting " _' y$ m6 X) O' w8 v2 x
March 7 - 10, 2010
2 [6 k8 v: w1 P0 c6 nHilton Head, SC USA
8 @$ p+ |5 E$ ], x$ pIn association with: Regenerative Medicine - Advancing to Next Generation Therapies
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Regenerative Medicine - Advancing to Next Generation Therapies
/ D% H, c9 l" {# g- EMarch 10 - 13, 2010
! O$ A) E/ ?7 J) n5 VHilton Head, SC USA
; S" \/ r3 a( g3 b& f0 m4 `In association with: 4th Biennial Heart Valve Biology and Tissue Engineering Meeting
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Keystone Symposia - New Paradigms in Cancer Treatment 5 z3 C1 M) q6 @
March 23 - 28, 2010 & C  p# b! Z2 Q7 m8 y/ g. l$ ~
Victoria, BC Canada 7 y4 \% ?; Y7 W9 A# T- N8 s3 k  ^
Late abstract submission deadline: Dec. 29, 2009
% B, k0 l: L: XDiscounted registration deadline: Jan. 25, 2010
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Keystone Symposia - Integration of Developmental Signaling Pathways
& Y6 z. U! R; J* e% pMarch 23 - 28, 2010 / h- ?* Y1 c" Q5 v0 J- c* d3 s0 w
Victoria, BC Canada ' x- `7 S$ ^* Q' A
Late abstract submission deadline: Dec. 29, 2009! |+ n& P' S9 G! v6 B
Discounted registration deadline: Jan. 25, 2010
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Keystone Symposia - Islet Biology
" K6 Z$ y+ H/ ^+ c6 t, H0 g( iApril 12 - 17, 2010 9 `5 m8 U9 |6 k. ~8 A
Whistler, BC Canada
0 \0 I4 f& J+ l/ |  E& _In association with: Keystone Symposia - Diabetes (held jointly)
" @9 ?# k9 T$ `" B9 NAbstract submission deadline: Dec. 14, 2009
% v) s1 h1 I8 O% |# E+ s# BScholarship application deadline: Dec. 14, 2009/ k7 E- t3 ^/ b. F9 \+ P8 \
Late abstract submission deadline: Jan. 15, 2010
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17th Annual Conference of the American Society for Neural Therapy & Repair 1 T& F4 T; V* b
April 29 - May 1, 2010
. M; F1 b2 ^1 x- Q: z+ `$ g- vClearwater, FL USA ' y! J& @  K9 n! M$ s
Abstract submission deadline: Dec. 15, 2009
- e& W7 O2 s! _7 {. F5 H+ pDiscounted registration deadline: Dec. 31, 2009" `9 d5 f0 e8 f' L" u
Hotel discount deadline: March 29, 2010
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& I/ Q. m7 H3 A5 K: `SBE's Second International Conference on Stem Cell Engineering
  k; f$ D- l! }6 K7 l9 vMay 2 - 5, 2010 ! S- ?- U/ _8 N
Boston, MA USA " G9 m" o- k1 i% V; S5 c
Abstract submission deadline: Jan. 22, 2010
/ g0 R5 ]" d* `Co-sponsored by the ISSCR
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/ P2 _/ E$ v& T4 p- Q0 j# p16th Annual ISCT Meeting 3 s1 p4 {# I( z, c- _& H
May 23 - 26, 2010
$ }5 q" L4 @: w1 S; `$ rPhiladelphia, PA USA
" ], R3 Q2 k4 x! ?# L- ^Abstract submission deadline: Feb. 1, 2010
6 ?' [/ N0 P3 t2 [- U8 V  O: C' HEarly registration deadline: Jan. 15, 2010
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ASAIO 56th Annual Conference 8 W4 F, J. z6 @4 {" N
May 27 - 29, 2010
% d5 _/ P( L3 V- n+ h3 B, [6 ]8 F4 iBaltimore, MD USA
4 F& Q# Q/ \$ d/ h  aAbstract submission deadline: Jan. 19, 2010
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ISSCR 8th Annual Meeting
0 u5 P; \* c, u( WJune 16 - 19, 2010
/ x# v6 N7 c- s4 d5 H* b9 A! J  B& eSan Francisco, CA USA 9 G8 A9 r% I1 H" ?0 h0 w
Abstract submission deadline: Jan. 14, 2010, c5 N) t; _; k" q) E6 w
Travel award application deadline: Jan. 14, 2010( b$ h: S5 M3 r& n' v+ K+ c2 G
Registration begins: Dec. 2009
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/ Z- d7 r) f: p  C2 E" v3rd International Congress on Stem Cells and Tissue Formation
/ G4 Q! q; A& b9 K/ d  f" ?& vJuly 11 - 14, 2010 " V% v7 l; \/ z: M) a% R
Dresden, Germany # e5 s" p! b9 I0 w$ ~: Y
Abstract submission deadline: Jan. 31, 2010. [8 x" ^* J; H8 r6 B( b" m
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Upcoming Courses:+ j% L' ^$ ?/ s- Y. C" k

- J0 j3 h7 o+ hStem Cells: A Pathway Through the Maze) l5 H0 B+ b; N6 Z1 ]
Dec. 10 - 11, 2009 * l4 a( I8 x5 Y- c  R
Oxford, United Kingdom
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Human Pluripotent Stem Cell Culture Methods Course
6 S/ i* S4 m* y4 l9 UMarch 8 - 10, 2010) n# T! }/ K6 h' b
Madison, WI USA9 A% P/ O) d% o3 m. u; L) M

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: F2 `# T( ?$ U7. Literature Highlights. ^  R; S& e7 x# V  {
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ISSCR 7th Annual Meeting Report:0 v0 T; Y2 S6 j, S+ b' D6 e
McKay, R. D., van der Kooy, D., Zwaka, T. P., and Lin, H. (2009). Stem cells in 2009. Cell Stem Cell 5, 483-489.; _# z8 M$ G1 c  W9 f) e
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Online highlights:
4 y; N& `( x. iCurrent Protocols in Stem Cell Biology continues to add new stem cell protocols monthly to their valuable online resource of methods and technologies in the field. Find these on their new Web site alongside newly developed online laboratory tools and calculators. Current Protocols.
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, l. c& y& Z8 M2 n( U' JWebinar—“iPS Cells - Breaking Down the Barriers to Therapeutics.” Learn more about disease-specific iPSCs and their potential applications from this Cell Press Webinar. If you missed the live event, you can still watch an archived version of the Webinar, and read Dr. Hans Schöler's answers to audience questions that couldn't be covered during the event itself.; o1 i) T7 x) F. |; ^1 Q
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Review:
- I$ E  |$ v6 F4 p  d, u. B# MSaha, K., and Jaenisch, R. (2009). Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell 5, 584-595.$ k! z, a6 i9 s) B

# `. |5 D  U5 DForum:
+ S7 r! d' D6 X/ ?" xAlexander, C. M., Puchalski, J., Klos, K. S., Badders, N., Ailles, L., Kim, C. F., Dirks, P., and Smalley, M. J. (2009). Separating stem cells by flow cytometry: reducing variability for solid tissues. Cell Stem Cell 5, 579-583.
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% ~# Y; ~4 V- v: E( S' _Review of recent literature:
  `# c1 T; F" ]1 |8 @Schinder, A. F., and Morgenstern, N. A. (2009). Adult neurogenesis is altered by GABAergic imbalance in models of Alzheimer's disease. Cell Stem Cell 5, 573-574.! @. `3 ^2 k5 O0 q5 d5 L
Commentary on Li et al., Cell Stem Cell 5, 634-645 and Sun et al., Cell Stem Cell 5, 624-633.
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Kellner, J. C., and Coulombe, P. A. (2009). SKPing a hurdle: Sox2 and adult dermal stem cells. Cell Stem Cell 5, 569-570.
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Chan, E. M., Ratanasirintrawoot, S., Park, I. H., Manos, P. D., Loh, Y. H., Huo, H., Miller, J. D., Hartung, O., Rho, J., Ince, T. A., et al. (2009). Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nat Biotechnol 27, 1033-1037.
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