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本帖最后由 细胞海洋 于 2010-1-19 08:22 编辑 % B% @4 r$ b3 m3 d+ U; D7 C
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Genes and common diseases presents an up-to-date
' S4 J: y1 ?0 Rview of the role of genetics in modern medicine,
) h, h& X% }& A* R5 h: K: B* A+ [) xreflecting the strengths and limitations of a genetic
6 d4 B, N( N0 Y& F* u6 A! L4 Q! sperspective.2 ]5 ]0 A( E8 B) f5 q
The current shift in emphasis from the study of5 m. X- w: A6 P& B( R, `0 _
rare single gene disorders to common diseases
7 G& f; `6 l# M# q% A7 I% Y, _1 nbrings genetics into every aspect of modern
" \* t6 @, L) n3 s8 Vmedicine, from infectious diseases to therapeutics.2 g( Z) T- J( r6 ~* m% `2 f7 ~
However, it is unclear whether this increasingly
% h( O |3 e" V# w$ E# `% p Zgenetic focus will prove useful in the face of major
- U* G0 ^, G. ^6 ?4 Genvironmental influences in many common" q3 {# z, r# {; ]+ Z1 i; W; R
diseases.
6 B4 I$ }* Z( Q: U! e4 t+ }, MThe book takes a hard and self-critical look at
7 C' t4 z. x( R( {' \) S' G2 Xwhat can and cannot be achieved using a genetic
+ K0 L& z9 J# M* K! a; Aapproach and what is known about genetic and! X R, v! j# j' \5 j2 F) e, c
environmental mechanisms in a variety of
3 |% Z: N0 o3 A% h7 Jcommon diseases. It seeks to clarify the goals of
* f& C8 K: ?( J# @: Q. x( a* m3 rhuman genetic research by providing state-of-the
; p a4 _' Y# v# n' u9 ?art insights into known molecular mechanisms* F& x3 `. Q1 `$ f+ l6 l
underlying common disease processes while at the
/ R6 e. k: W- Y: B- f. xsame time providing a realistic overview of the
$ l5 T9 }& f' N0 u, Nexpected genetic and psychological complexity.
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