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iPS cell publications & timeline5 ?! w( q: ^* c7 S# h( T( Q- ^
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Shinya Yamanaka, Pluripotency and Nuclear Reprogramming, Keystone conference, 28 March 2006; www.keystonesymposia.org/Meetings/ViewPastMeetings.cfm?MeetingID=786
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2 @" k$ c3 `9 q3 V9 m' pShinya Yamanaka, Identification Of Factors That Generate ES-Like Pluripotent Cells From Fibroblast Culture, ISSCR meeting, Toronto, July 2006; www.abstractonline.com/viewer/viewAbstractPrintFriendly.asp?CKey={23482185-19E3-4771-B8CF-FDBD125BAB66}&SKey={9426630B-B824-4F8F-93F7-6C940384237C}&MKey={743B38D5-9EAD-49CC-B2C5-497EBCE87271}&AKey={70E49A1A-9665-43B3-8BAA-55C6A8F9A624}
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) ^+ b/ c$ i# Y2 ]* {2 \7 M% nGretchen Vogel,“Four genes confer embryonic potential”, Science 313, 27, 7 July 2006; published online 3 July 2006; doi: 10.1126/science.313.5783.272 Q2 [& Z/ ]" f) \$ ^2 n$ K. p
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+ x+ ?; {9 b0 b$ G5 hErika Check, “Simple recipe gives adult cells embryonic powers”, Nature 442, 11, 6 July 2006; published online 4 July 2006; doi: 10.1038/442011a
+ k3 b$ A) j( o; e! {# _& ~PEER-REVIEWED PUBLICATIONS
3 \8 P. a. {" H8 @(Primary research literature, excluding commentaries)
+ w, r* E% `9 [(NOTE: bolding to emphasize important points, yellow highlight for human iPS cells)$ W- F9 q% ?7 H  ?* n( l( p# f+ B
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Takahashi K and Yamanaka S, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, Cell 126, 663-676, 25 August 2006, doi: 10.1016/j.cell.2006.07.0241 ^7 \4 x3 K' Q& x
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, R& D9 X5 }: w8 c9 ^Okita K et al., Generation of germline-competent induced pluripotent stem cells, Nature 448, 313-317, 19 July 2007; online 6 June 2007, doi: 10.1038/nature05934% h- R! I) P& O7 F
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$ L; d9 S, c6 X$ Q& Q. zWernig M et al., In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state, Nature 448, 318-324, 19 July 2007; published online 6 June 2007, doi: 10.1038/nature05944
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9 ]( H1 w4 C4 K4 E+ T. P# [Maherali N et al., Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution, Cell Stem Cell 1, 55-70, July 2007; published online 6 June 2007, doi: 10.1016/j.stem.2007.05.014
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Meissner A et al., Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells, Nature Biotechnology 25, 1177-1181, October 2007; published online 27 August 2007, doi: 10.1038/nbt1335# F0 v, _! S1 u5 E1 X+ Y& l/ ]) Q8 S
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Blelloch R et al., Generation of induced pluripotent stem cells in the absence of drug selection, Cell Stem Cell 1, 245-247, Sept 2007, doi: 10.1016/j.stem.2007.08.008: j1 l+ A# r, ]% G* F' B+ b$ }1 l
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Takahashi K et al., Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell 131, 861-872, 30 November 2007; published online 20 November 2007, doi: 10.1016/j.cell.2007.11.019/ ^1 d, F9 g: Z( d. U) k7 |; ]% }
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Yu J et al., Induced pluripotent stem cell lines derived from human somatic cells, Science 318, 1917-1920, 21 December 2007, published online 20 November 2007, doi: 10.1126/science.1151526% w  `0 e! ~/ w9 W' A
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: r# h+ i5 U2 l7 L& R8 }" ?Nakagawa M et al., Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts, Nature Biotechnology 26, 101-106, January 2008, published online 30 November 2007, doi: 10.1038/nbt1374
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1 a' F; T. T/ j" W, P# D: [Hanna J et al., Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin, Science 318, 1920-1923, 21 December 2007, online 6 Dec 2007, doi: 10.1126/science.1152092
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* H% L: y: i, W' ?Park I-H et al., Reprogramming of human somatic cells to pluripotency with defined factors, Nature 451, 141-147, 10 January 2008, published online 23 December 2007, doi: 10.1038/nature06534
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Wernig W et al., C-Myc is dispensable for direct reprogramming of mouse fibroblasts, Cell Stem Cell 2, 10-12, 10 January 2008, published online 28 December 2007, doi: 10.1016/j.stem.2007.12.001, ?+ P7 i7 f. f# d
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Yamanaka S, Induction of pluripotent stem cells from mouse fibroblasts by four transcription factors, Cell Proliferation 41 (suppl 1), 51-56, January 2008, doi: 10.1111/j.1365-2184.2008.00493.x (www3.interscience.wiley.com/journal/119410896/abstract)
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Brambrink T et al. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells, Cell Stem Cell 2, 151–159, 7 February 2008, online 6 February 2008, doi: 10.1016/j.stem.2008.01.004( Y. N# f5 I( M& ?3 k
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Aoi T et al., Generation of pluripotent stem cells from adult mouse liver and stomach cells, Science 321, 699-702, corrected 1 August 2008; published online 14 February 2008, doi:10.1126/science.1154884
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% v) M3 H8 ~: p8 U8 t! L' zStadtfeld M et al., Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse, Cell Stem Cell 2, 230-240, March 2008, published online 14 February 2008, doi:10.1016/j.stem.2008.02.001
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Lowry WE et al., Generation of human induced pluripotent stem cells from dermal fibroblasts, Proc. Natl. Acad. Sci. USA 105, 2883-2888, 26 February 2008; published online 16 February 2008, doi: 10.1073/pnas.0711983105
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Wernig M et al., Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson’s disease, Proc. Natl. Acad. Sci. USA 105, 5856-5861, 15 April 2008, doi: 10.1073/pnas.0801677105. a: M: V) j3 J+ R7 `# Z! F
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( J( E, C/ T# H, W( }$ u( E/ CHanna J et al., Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency, Cell 133, 250-264, 18 April 2008, doi: 10.1016/j.cell.2008.03.028
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Schenke-Layland K et al., Reprogrammed Mouse Fibroblasts Differentiate into Cells of the Cardiovascular and Hematopoietic Lineages, Stem Cells 26, 1537-1546, June 2008; published online 1 May 2008, doi: 10.1634/stemcells.2008-0033% d$ j+ l, Z; S
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Liao J et al., Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors, Cell Research 18, 600-603, May 2008, doi: 10.1038/cr.2008.515 |2 v$ Y, ?# [  Q) r
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2 e+ @$ B6 u' V. dStadtfeld M et al., Reprogramming of pancreatic β cells into induced pluripotent stem cells, Current Biology 18, 890-894, 24 June 2008, published online 22 May 2008, doi: 10.1016/j.cub.2008.05.010
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4 `# y' h" E6 \' B1 X3 z: ?6 `Mikkelsen TS et al., Dissecting direct reprogramming through integrative genomic analysis, Nature 454, 49-56, 3 July 2008; published online 28 May 2008, doi: 10.1038/nature07056# K4 n' o+ [4 @) @0 ^  m
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6 o) Y9 h  ?6 w$ VMali P et al. Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts, Stem Cells 26, 1998-2005, Sept 2008; published online 29 May 2008, doi:10.1634/stemcells.2008-03469 b/ Y  j0 P& S. n* {
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$ ~& ^( A5 l! k6 {+ P% @( _Shi Y et al., A combined chemical and genetic approach for the generation of induced pluripotent stem cells, Cell Stem Cell 2, 525-528, June 2008, doi: 10.1016/j.stem.2008.05.011
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8 [6 Y9 m% u2 `Huangfu D et al., Induction of pluripotent stem cells by defined factors in greatly improved by small-molecule compounds, Nature Biotechnology 26, 795-797, July 2008; published online 22 June 2008, doi: 10.1038/nbt1418# M) l; N, S9 A
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8 R0 J' t8 M3 xPark I-H et al. Generation of human-induced pluripotent stem cells, Nature Protocols 3, 1180-1186, July 2008; published online 26 June 2008, Corrected online 4 September 2008, doi: 10.1038/nprot.2008.92
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Kim JB et al., Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors, Nature 454, 646-650, 31 July 2008; published online 29 June 2008, doi: 10.1038/nature070619 ?  d% e$ n  d. t2 g. M6 Y
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Wernig M et al., A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types, Nature Biotechnology 26, 916-924, August 2008; published online 1 July 2008; doi: 10.1038/nbt1483( T7 f4 ?1 M& L7 I" l% _; |8 b
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Duinsbergen D et al., Induced pluripotency with endogenous and inducible genes, Experimental Cell Research 314, 3255-3263, 15 October 2008, published online 9 July 2008, doi: 10.1016/j.yexcr.2008.06.024" F. |( W5 s6 q( {) c/ c
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Narazaki G et al., Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cell, Circulation 118, 498-506, 29 July 2008, published online 14 July 2008, doi: 10.1161/CIRCULATIONAHA.108.769562
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; m. O2 }5 f7 J2 o9 rMauritz C et al., Generation of functional murine cardiac myocytes from induced pluripotent stem cells, Circulation 118, 507-517, 29 July 2008, published online 14 July 2008, doi: 10.1161/CIRCULATIONAHA.108.778795! _9 l" J4 u" w2 h& f4 M; X0 @
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/ |2 S9 C! A1 `. oEminli S et al., Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression, Stem Cells 26, 2467-2474, October 2008; published online 17 July 2008, doi: 10.1634/stemcells.2008-0317
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1 [2 S  t/ l( Z% kDimos JT et al., Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons, Science 321, 1218-1221, 29 August 2008; published online 31 July 2008, doi: 10.1126/science.1158799
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Marson A et al., Wnt signaling promotes reprogramming of somatic cells to pluripotency, Cell Stem Cell 3, 132-135, 7 August 2008, doi: 10.1016/j.stem.2008.06.0198 G0 D! y& E! ~7 L3 q5 g
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, |6 N9 ^7 f2 S  G+ B1 ?9 E! I  YPark I-H et al., Disease-specific induced pluripotent stem cells, Cell 134, 877-886, 5 Sept 2008; published online 7 August 2008, doi: 10.1016/j.cell.2008.07.041
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5 \) l+ D7 v  [+ MTateishi K et al., Generation of insulin-secreting islet-like clusters from human skin fibroblasts, Journal of Biological Chemistry 283, 31601-31607, 14 November 2008, published online 9 Sept 2008, DOI: 10.1074/jbc.M806597200( J! R! ^4 F3 @% D" V; i
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" g- _# T, [' z5 f3 |Maherali N et al., A high-efficiency system for the generation and study of human induced pluripotent stem cells, Cell Stem Cell 3, 340-345, 11 Sept 2008, doi: 10.1016/j.stem.2008.08.003
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Hockemeyer D et al., A drug-inducible system for direct reprogramming of human somatic cells to pluripotency, Cell Stem Cell 3, 346-353, 11 Sept 2008, doi: 10.1016/j.stem.2008.08.014# {+ Y+ E3 ?3 h. Y7 I5 V
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* b  `- P7 H2 FStadtfeld M et al., Induced pluripotent stem cells generated without viral integration, Science 322, 945-949, 7 November 2008; published online 25 Sept 2008, doi: 10.1126/science.1162494' f/ ~/ {0 p3 o4 a) C. F* n
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Qin D et al., Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors, Journal of Biological Chemistry 283, 33730-33735, 28 November 2008; published online 1 October 2008, doi: 10.1074/jbc.M806788200
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9 D7 p; @+ b2 d  K6 |7 E: COkita K et al., Generation of mouse induced pluripotent stem cells without viral vectors, Science 322, 949-953, 7 November 2008; published online 9 October 2008, doi: 10.1126/science.1164270
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% \1 G% x/ E4 ?7 m- D1 x7 y( bHuangfu D et al., Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2, Nature Biotechnology 26, 1269-1275, published online 12 October 2008, doi: 10.1038/nbt.15028 Q; N  _  }1 @
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- J+ \! N2 b& {5 q4 U# W$ B7 d) T% bAasen T et al., Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes, Nature Biotechnology 26, 1276-1284, November 2008; published online 17 October 2008, doi:10.1038/nbt.1503
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) B0 m) z* q% H$ G7 aSilva J et al., Promotion of reprogramming to ground state pluripotency by signal inhibition, PLoS Biology 6(10): e253, published 21 October 2008, doi:10.1371/journal.pbio.0060253
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Shi Y et al., Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds, Cell Stem Cell 3, 568-574, 6 November 2008, doi: 10.1016/j.stem.2008.10.004! v3 k( H& ~7 S; h' C. v7 u
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: B" @% g* m4 m) v! {/ \" ]: fZhao Y et al., Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation, Cell Stem Cell 3, 475-479, 6 November 2008, doi: 10.1016/j.stem.2008.10.0024 E% d7 h8 U, o) S# M9 k
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Varas F et al., Fibroblast derived induced pluripotent stem cells show no common retroviral vector insertions, Stem Cells 27, 300-306, February 2009, published online November 13, 2008; doi:10.1634/stemcells.2008-0696
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% i5 `, Y7 d% L/ q- ILiu H et al., Generation of Induced Pluripotent Stem Cells from Adult Rhesus Monkey Fibroblasts, Cell Stem Cell 3, 587-590, 4 December 2008, 10.1016/j.stem.2008.10.014
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Sommer CA et al., iPS Cell Generation Using a Single Lentiviral Stem Cell Cassette, Stem Cells 27, 543-549, March 2009, published online December 18, 2008, doi: 10.1634/stemcells.2008-1075
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Ebert AD et al., Induced pluripotent stem cells from a spinal muscular atrophy patient, Nature 457, 277-280, 15 January 2009; published online 21 December 2008; doi:10.1038/nature07677+ @# g% V5 C! `% ?
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( {" p3 v* e. aCarey BW et al., Reprogramming of murine and human somatic cells using a single polycistronic vector, Proc. Natl. Acad. Sci. USA 106, 157-162, 6 January 2008, published online 24 December 2008, doi: 10.1073/pnas.0811426106/ i* B4 n; }* ^7 @. w& V
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Choi K-D et al., Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells, Stem Cells 27, 559-567, March 2009, published online 8 January 2009, doi: 10.1634/stemcells.2008-0922- X# u& e# }# b  T7 ?
54.
0 f$ y  t3 N8 JLiao J et al., Generation of Induced Pluripotent Stem Cell Lines from Adult Rat Cells, Cell Stem Cell 4, 11-15, 9 January 2009, doi: 10.1016/j.stem.2008.11.013
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6 y! D/ W$ p! e$ _( M- lLi W et al., Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors, Cell Stem Cell 4, 16-19, 9 January 2009, doi: 10.1016/j.stem.2008.11.014" E( k$ J# M$ @, u5 C
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5 A5 H$ t) |/ K3 \. F: V+ f. C* R2 h4 kFeng B et al., Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb, Nature Cell Biology 11, 197-203, February 2009, published online 11 January 2009; doi: 10.1038/ncb1827
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8 m/ x, o$ {0 p/ L7 z& O8 DMarkoulaki S et al., Transgenic mice with defined combinations of drug-inducible reprogramming factors, Nature Biotechnology 27, 169-171, February 2009; published online 18 January 2009; doi:10.1038/nbt.1520
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+ M' L% c' |; @3 ~9 M+ hXu D et al., Phenotypic correction of murine hemophilia A using an iPS cell-based therapy, Proc. Natl. Acad. Sci. USA 106, 808-813, 20 January 2009, doi: 10.1073/pnas.08120901065 ]2 `! R9 O+ v) H" J  i. t
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# n( {. d, b9 \6 u2 wPark TS et al., Derivation of Primordial Germ Cells From Human Embryonic and Induced Pluripotent Stem Cells Is Significantly Improved By Co-Culture With Human Fetal Gonadal Cells, Stem Cells 27, 783-795, published online 22 January 2009, doi: 10.1002/stem.13
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" U# Z2 J4 F  W6 T1 \& D8 U& t9 _Sridharan R et al., Role of the Murine Reprogramming Factors in the Induction of Pluripotency, Cell 136, 364–377, 23 January 2009, doi: 10.1016/j.cell.2009.01.001# k9 h% {; I% @7 i& r& s, r
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Kim JB et al., Oct4-Induced Pluripotency in Adult Neural Stem Cells, Cell 136, 41l-419, 6 February 2009, doi: 10.1016/j.cell.2009.01.0230 t+ m0 A; T7 t( W
FAMILY RESEARCH COUNCIL WASHINGTON, D.C. 20001 202-393-2100 www.frc.org
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Marion RM et al., Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells, Cell Stem Cell 4, 141-154, 6 February 2009, doi: 10.1016/j.stem.2008.12.010
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Zhang J et al., Functional cardiomyocytes derived from human induced pluripotent stem cells, Circulation Research 104, e30-e41, published online 12 February 2009, doi: 10.1161/CIRCRESAHA.108.192237
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; q5 p7 @6 J+ a5 cChang C-W et al., Polycistronic Lentiviral Vector For Hit and Run Reprogramming Of Adult Skin Fibroblasts To Induced Pluripotent Stem Cells, Stem Cells 27, 1042-1049, May 2009, published online 12 February 2009, doi: 10.1002/stem.39
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Senju S et al., Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells, Stem Cells 27, 1021-1031, May 2009, published online 13 February 2009, doi: 10.1002/stem.33; H& \" \- f$ Y
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Guo G et al., Klf4 reverts developmentally programmed restriction of ground state pluripotency, Development 136, 1063-1069, 1 April 2009, published online 18 February 2009, doi:10.1242/dev.030957
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* @4 G% k" F- l) |2 Y0 LKarumbayaram S et al., Directed Differentiation of Human Induced Pluripotent Stem Cells Generates Active Motor Neurons, Stem Cells 27, 806-811, April 2009, published online 23 February 2009 doi: 10.1002/stem.31
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6 ?% Y6 ~) ?9 j# [, w2 uShao L et al., Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame, Cell Research 19, 296-306, March 2009, published online 24 February 2009,. doi: 10.1038/cr.2009.20
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/ t* M9 E9 p, N, |5 A. c3 `Taura D et al., Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells, FEBS Letters 583, 1029-1033, 18 March 2009, published online 27 February 2009, doi: 10.1016/j.febslet.2009.02.031
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7 \: p' s0 s7 ]# q- B+ H& X' JChambers SM et al., Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling, Nature Biotechnology 27, 275-280, March 2009; published online 1 March 2009; doi:10.1038/nbt.1529: b  P% d* f, D
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& s  X& }& b7 T# G& k: YKaji K et al., Virus-free induction of pluripotency and subsequent excision of reprogramming factors, Nature 458, 771-775, 9 April 2009, published online 1 March 2009, doi: 10.1038/nature07864
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Woltjen K et al., piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells, Nature 458, 766-770, 9 April 2009, published online 1 March 2009, doi: 10.1038/nature07863
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" E; E4 {; n& H+ F" N4 }Zhang D et al., Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells, Cell Research 19, 429-438, April 2009, published online 3 March 2009, doi: 10.1038/cr.2009.280 C5 F+ r! L/ w
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Soldner F et al., Parkinson’s disease patient-derived induced pluripotent stem cells free of viral reprogramming factors, Cell 136, 964-977, 6 March 2009, doi: 10.1016/j.cell.2009.02.013
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Loh Y-H et al., Generation of induced pluripotent stem cells from human blood, Blood published online 18 March 2009, doi: 10.1182/blood-2009-02-2048001 C/ c( N0 v+ \" q5 i  b! N
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: |* F3 x6 l, {. r" j9 u, B' bYu J et al., Human induced pluripotent stem cells free of vector and transgene sequences, Science 324, 797-801, 8 May 2009, published online 26 March 2009, doi: 10.1126/science.1172482
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( U9 j  D, C$ \Deng J et al., Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming, Nature Biotechnology 27, 353-360, April 2009; published online 29 March 2009; doi:10.1038/nbt.1530
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+ Z9 U8 }  [1 K) ]7 k- `Ball MP et al., Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells, Nature Biotechnology 27, 361-368, April 2009, published online 29 March 2009, doi: 10.1038/nbt.1533
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; B: W2 W/ N6 |* a, d$ C# i" {$ H# FYusa K et al., Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon, Nature Methods published online 31 March 2009, doi:10.1038/nmeth.1323' L: f: n3 L3 T8 O
80.
* c! d- ~7 S' ?5 I. P5 Q; MJudson RL et al., Embryonic stem cell-specific microRNAs promote induced pluripotency, Nature Biotechnology 27, 459-461, May 2009, published online 12 April 2009, doi: 10.1038/nbt.1535
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xuefei200403

xinku

xnbobo

有中文的么？

双刀

谢谢

lorey

支持楼主！

qgjin

楼主辛苦了！

chuanbaozang

很多很强大，哈哈，谢谢。以后可有地方遴选文献了。

pujixing

Thanks!) |3 Z9 t, @( D" E" C; S( \9 z$ E* ?
best( A  ^' j& G8 _& e% W) g7 [9 x
pujixing

zlx0814

2010的没有哦。我们广州这边就发了两个cell stem cell呢/ L% v4 z/ J' d, }& f# M1 _
Jonathan 发表于 2010-5-6 12:39

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    欢迎补充啊！:)

Jonathan

2010的没有哦。我们广州这边就发了两个cell stem cell呢