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本帖最后由 细胞海洋 于 2010-5-7 15:56 编辑 " u1 z6 s& \2 r8 f$ F
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. o) K; T0 o7 C+ r5 r5 z# i8 r; {封面故事——Alternative splicing allows a single gene to produce more than one protein, and shapes how genetic information controls cellular processes. The Frey and Blencowe labs at the University of Toronto have combined forces to develop a 'splicing code' that predicts how hundreds of RNA features work together to regulate tissue-dependent alternative splicing for thousands of exons (see News page 16). The code has been used to predict how alternative splicing acts in various developmental and neurological processes, and the code has been incorporated into a web tool that allows researchers to scan uncharacterized exon and intron sequences to predict tissue-dependent splicing patterns. Cover graphic by Brendan Frey.
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发表于 2010-5-7 15:29
发表于 2010-5-7 15:57
