stem cell news 100819-26

kittybruce

Glance at last issue:
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"This suggests that the neural stem cell niche in the brain may be harboring cancer stem cells, thus providing novel therapy targets. We hypothesize that higher radiation doses to these niches improve patient survival by eradicating the cancer stem cells."--A study from the Radiation Oncology Department at UCLA's Jonsson Comprehensive Cancer Center.
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“While these projects principally reflect our core strengths in small and large molecule development and are directed at modulation of stem cells, we are also interested to understand the progress being made in cell-based regenerative approaches to disease...While we bring a wealth of drug discovery and development experience, we want to work with key opinion leaders and biotechs that are leading in this field. Putting their expertise together with our own experience represents the best route to making a significant impact in developing new regenerative medicines.”--Alan Lamont, director, Science & Technology Alliances.' n9 J) O- n) G) o* n
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“The market could very much be like that for monoclonal antibodies, which took 25 years to mature.”--Dr Alain Vertès, global alliance director, Roche and sloan fellow, from London Business School.
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( J7 q" P0 p2 W) \; n3 ^“Our results demonstrate that quiescence is a double‐edged sword, protecting hematopoetic stem cells from cellular stress but rendering them intrinsically vulnerable to mutagenesis following DNA damage.”--senior author Emmanuelle Passegué, PhD, associate professor of medicine (division of hematology/oncology) and a member of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF.
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* Y, ~+ u' j. e" i6 R# I1 s$ G“This program provides a unique opportunity for engineers to generate standardized and quantitative methods for stem cell isolation, characterization, propagation and differentiation. These techniques must be developed in a scalable manner to efficiently produce sufficient numbers of stem cells and derivatives in accessible formats in order to yield a spectrum of novel therapeutic and diagnostic applications of stem cells.”--Robert M. Nerem, professor emeritus of the George W. Woodruff School of Mechanical Engineering at Georgia Tech, director of the Georgia Tech/Emory Center (GTEC) for Regenerative Medicine." \4 o+ A, e+ {- A8 N
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"If we want to use them for clinical therapies, we have to understand how aging affects the quality of the stem cell you can make. They may have properties in common with embryonic stem cells, but they might also have properties in common with an 80-year-old patient, like an increased susceptibility to cancer."--Amy Ralston, an assistant professor of molecular, cell, and developmental biology at UC Santa Cruz.4 E' e' ]3 f" J  I0 E2 F( M

$ i9 m5 O2 u' j$ R- I  h6 s"If we win, the entire regulatory structure for autologous cell processing, with or without culture, will be rewritten such that any physician using good practices and treating patients responsibly can use stem cells as part of his or her medical practice."--Christopher Centeno, Regenerative Sciences' medical director.
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# I6 u" k2 a- _7 t. s"Because stem cells have the ability to differentiate and proliferate, there has been a great increase in research into stem cell-based regenerative medicine over the last decade. Paralleling this trend in research is a similar differentiation and proliferation of stem cell journals...The development of a more mature stem cell research arena will hinge on the quality of stem cell science peer review."--Drs. Paul Sanberg of the Department of Neurosurgery and Brain Repair at the University of South Florida.7 J4 R4 T6 c' P( g9 H- g' R7 |

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/ }! i' d. ]0 ?& i3 z9 JThis issue:
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lixiaodong

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张也行

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xuyongan2000

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