《细胞-干细胞》[Cell Stem Cell]2010年9月3日出版pdf全文

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3 September, 2010 Volume 7, Issue 3
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Editors' Notes% b* F  ?. S9 h: G. H7 o8 ^

, G0 a! e) r: F9 JPreviews
8 N- n7 x# C! \9 O9 F. dCancer Cell of Origin: Spotlight on Luminal Progenitors; a% x0 b, h5 z' Y
Christine L. Chaffer, Robert A. Weinberg
. |4 \3 S. P$ G4 D- aMicroarraying for Mechanosensivitity7 m, N  i$ q& M# |$ A
David V. Schaffer5 O+ [, `; \- ?* b6 C( Z: \3 K
The STATs on Naive iPSC Reprogramming
6 v; E9 N' N& z2 a  h- OJacob H. Hanna
4 g" A" O% x2 ]( t8 O9 ~1 \  uHypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword; w6 \8 e" M. q0 u) s
Patrick J. Pollard, Kamil R. Kranc# c, }0 @, W6 L) ^

/ q  g+ g7 q& |; i& {' W7 qBrief Report& d6 }# X5 }9 X* y+ C
Tumor-Initiating Cells Are Rare in Many Human Tumors! w+ R& V8 ]) g! B2 E; |1 z
Kota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui% A2 [  O* ~1 j* R7 ]

/ i8 m+ F- d2 \# L/ f$ aForum5 {. J6 Z6 U0 d
The Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases1 _5 t* w- k9 q
Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté2 L, G, u8 s8 e$ J3 ~8 Y" t
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Reviews
. \5 n+ h; ^1 F2 i. r3 o4 GPolycomb Group Proteins Set the Stage for Early Lineage Commitment
3 S4 w) R, f* `. n. qLauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer
  _1 Z- I  _+ Z% TPolycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
% L5 J9 @: r. G" YMartin Sauvageau, Guy Sauvageau# a9 d1 j% j- J: j7 L' ^

# G) v' T; W. ]% gISSCR: President's Note7 I$ M6 `% B& F8 @+ t
Toward a Knowledge of Causes" b9 k1 I% R/ B* {
Elaine Fuchs3 n2 ^5 z6 k1 I  u7 U
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Articles
7 g% s5 @% k. T; U7 HStat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency6 I1 [4 p& Y& \# d& u/ m) C
Jian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith' [) B# b! P& `4 W; s! Z  o% y# U
Female Human iPSCs Retain an Inactive X Chromosome7 Q8 ?1 p2 U* G9 ^% W
Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath
# r, ^! ]3 f9 S4 mMyc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells
+ p8 I: Q( T' _: G* o2 kKeriayn N. Smith, Amar M. Singh, Stephen Dalton
. k' ?7 H2 x) Z* cFunctional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation
' X  X% E8 X4 \# C2 {  U$ RMirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle: A' ^0 X: |- e7 r7 D) y6 H) {/ a2 S
Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling: }+ b. W' w, Y. ^; V7 k* b
Sacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas8 Z" r& P; m, S: \9 Z1 \+ T+ T
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
0 \5 ^# w6 x# n$ d. ^. \Tugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek( V3 q9 Q8 }+ Y7 T6 V' t5 p
Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells  s2 F' V) \7 |; P; y7 f
Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda' |/ j' }( y# g  t4 o
Featured Article5 R9 P7 I" u2 f  L
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells: i1 A9 p) x* b. G' G) H
Gemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley" J* D% a$ Y9 z) V$ e1 Q
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快乐小郎

说的真有道理啊！

chinagalaxy

感觉好像在哪里看过了，汗~  

dd赤焰

顶也～  

天蓝色

干细胞研究人员的天堂

myylove

呵呵,支持一下哈  

apple0

顶你一下.  

小小C

不错，感谢楼主

myylove

21世纪，什么最重要——我！  

hmhy

晕死也不多加点分