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本帖最后由 细胞海洋 于 2010-9-6 20:03 编辑
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8 W% ?* R# g+ b' F7 Y2 y) R3 September, 2010 Volume 7, Issue 3
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Editors' Notes
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Previews
$ H( \1 C" z2 \Cancer Cell of Origin: Spotlight on Luminal Progenitors, D1 I4 b: d4 ~% d) z: a
Christine L. Chaffer, Robert A. Weinberg4 ^: D+ e. c$ S' [
Microarraying for Mechanosensivitity( W+ p9 f3 X7 X
David V. Schaffer; g% o4 e+ x8 k- Y. Y
The STATs on Naive iPSC Reprogramming8 _9 s9 `& `* A$ T' B
Jacob H. Hanna" c* J5 }& N6 \6 |7 D6 t5 C
Hypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword
6 t4 L0 S6 u! Y, L+ w! i! a M5 [Patrick J. Pollard, Kamil R. Kranc3 \& F' S2 l6 A9 r9 | y2 U5 L1 d" j
% x" B s& F3 r# \/ c# C' WBrief Report9 d9 Y( F* U/ a8 j. l; F1 x
Tumor-Initiating Cells Are Rare in Many Human Tumors
8 ?) b% n9 S1 ?" s) w1 y, vKota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui
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7 N) l. C2 a/ u+ i- NForum# W" H5 C0 o5 v+ k8 c
The Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases* l. ?/ C- j8 L
Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté. b6 m+ Z e* \% z( t" k& k3 b0 n; H
5 n, S- D- N5 a8 R# y% uReviews
& [+ X4 K s! Y# r2 DPolycomb Group Proteins Set the Stage for Early Lineage Commitment& t% E# m5 V+ ?
Lauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer
) l' [7 ^; ~ v! ?Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer: o, `) d* j6 d! i
Martin Sauvageau, Guy Sauvageau0 L) H G5 @5 l5 o. N( v
: P3 J8 c- e7 M$ N$ BISSCR: President's Note
# B8 ]- Q6 D1 F. iToward a Knowledge of Causes9 z2 U. E7 @+ w" v5 Z
Elaine Fuchs
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Articles
# t" m8 A/ {6 P! n/ R# E+ S0 ^" DStat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency0 {5 l5 }% p+ m3 l
Jian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith1 i7 V2 `/ M& g- F
Female Human iPSCs Retain an Inactive X Chromosome
; i0 L: y# C6 R* r2 |Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath, @2 a9 W* \' f p
Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells
; z1 |0 D, ]/ M yKeriayn N. Smith, Amar M. Singh, Stephen Dalton: N) Q/ k7 V2 V
Functional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation
- Q" I6 H- d. ?8 ^9 QMirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle" G5 U: G+ p1 h) _
Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling
3 V) L- ?/ e! u" M' J5 {2 ^Sacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas3 S+ m }5 h% G6 E6 G0 k
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
" Z- D4 Y+ L9 A& D* u. y& ETugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek7 l# Q( S6 v- H! Y- B" A6 }7 ^
Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells# ~3 Y7 _3 s$ ?5 s* [
Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda
$ {2 V, o" {1 k$ hFeatured Article
) C# p& `6 Y9 U$ ]/ Q: r& }/ cBRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
1 m, R, x8 s3 F& k: eGemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley% E/ Y6 ]+ W1 K
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发表于 2010-9-6 15:44
发表于 2010-9-7 18:30
