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本帖最后由 细胞海洋 于 2010-9-6 20:03 编辑
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3 September, 2010 Volume 7, Issue 36 [- [7 { _6 P: l2 Z& a w: l
6 ~) M' e/ e7 Z. U& e6 lEditors' Notes' N0 n5 [, p9 i$ e
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Previews
% t9 F! ~* I( r8 P \- S: iCancer Cell of Origin: Spotlight on Luminal Progenitors+ ]1 G3 C. }; `# Q+ N+ @
Christine L. Chaffer, Robert A. Weinberg
+ |3 _; [+ m6 N* L0 i F9 ~* c& rMicroarraying for Mechanosensivitity
* ?0 Y# t, j0 Y4 J. G" n* P6 v; mDavid V. Schaffer
# h! L! u$ \1 [6 H- Q, c2 yThe STATs on Naive iPSC Reprogramming
9 K7 t, S1 @+ l8 `0 W: xJacob H. Hanna
, |3 W* A, T4 X6 u$ uHypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword
! Y- t: s( d& G8 pPatrick J. Pollard, Kamil R. Kranc8 `6 k2 T- S6 S. }2 t$ u2 m6 ^
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Brief Report0 X. Y( X0 W) `
Tumor-Initiating Cells Are Rare in Many Human Tumors& w. A2 e5 `8 k, m
Kota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui
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- o$ O6 x9 b4 l7 [ J& jForum6 w, a* ~9 r/ D& e3 F( O
The Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases
& J D1 W X+ _* y! v$ l* ^Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté+ m# F( E( ]. R. \
7 m, v! a, S# t0 a! rReviews
6 p+ F# Z9 Q9 d* F1 `Polycomb Group Proteins Set the Stage for Early Lineage Commitment0 Y" \2 X* q. ^* y% ^
Lauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer
0 c8 U; ^5 j" Y! R3 sPolycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
1 O0 {$ Z& l3 a. h7 W4 MMartin Sauvageau, Guy Sauvageau
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8 a k Q! I" I- SISSCR: President's Note; C: Y7 u8 ~, j% K( T
Toward a Knowledge of Causes
# i- r+ c/ A6 B. m' t2 T9 aElaine Fuchs
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, M* p" u2 s" t0 l7 s8 k7 j; z, X1 I- pArticles
/ I! {& |' C0 k8 I; C! H4 q7 oStat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
* W7 j' | E7 k: z/ s3 k. C9 m3 jJian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith4 P+ o6 L3 J5 S* w- H
Female Human iPSCs Retain an Inactive X Chromosome; A+ @: _; g9 \/ i+ y% g
Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath6 o. T: A, A: {, `7 u& b
Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells1 M+ { g0 H. ?/ T8 r/ e
Keriayn N. Smith, Amar M. Singh, Stephen Dalton
1 s# r1 A$ H: _- C9 m7 i; iFunctional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation
. P- L: U; k$ S( G- m6 RMirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle P& u+ P* [) ?& L, [3 K G
Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling$ O1 E8 G/ r0 E, o* W
Sacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas( j& j% Z: x8 c S1 C
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche$ I8 c, M; I& d$ s1 _& M
Tugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek
2 N) d) w+ d" ^Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
) O+ z4 A* @7 z& dKeiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda0 R9 J; H! e6 C1 s5 w9 p
Featured Article
$ l1 c& @( Z7 Q! B( UBRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
s- Z/ @+ b4 P, h: gGemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley
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