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本帖最后由 细胞海洋 于 2010-9-6 20:03 编辑
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3 September, 2010 Volume 7, Issue 3
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Editors' Notes9 d% K9 x9 h. Q4 m
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Previews
G4 a' Y {6 b' ? W E2 n+ [- lCancer Cell of Origin: Spotlight on Luminal Progenitors# M) l: Q' |6 C6 Z/ v& ^- ]
Christine L. Chaffer, Robert A. Weinberg' l3 M& t( i: m6 y$ b+ ^; O
Microarraying for Mechanosensivitity3 J& u' r; @( z) Z8 A7 L! T8 j t
David V. Schaffer
7 K, o5 h" h2 f- `0 c$ m, \The STATs on Naive iPSC Reprogramming9 x: S t5 i; m/ O, o
Jacob H. Hanna
4 q8 n& i8 @4 k, F0 HHypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword9 @3 q: U8 ]- [: f1 r7 G
Patrick J. Pollard, Kamil R. Kranc: l' }) ?/ u, H' E1 U! N
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Brief Report! a- a3 K5 U: c( v3 J, f
Tumor-Initiating Cells Are Rare in Many Human Tumors
3 {0 ~5 @/ X7 W2 d5 XKota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui6 M( [% @' m5 G5 G1 k* R& Z9 p
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Forum
& R* j0 I$ u6 Y5 @+ x XThe Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases
8 ^) J0 \% M3 m6 FScott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté- k0 W' h Z% y
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Reviews0 ^! K. b Z. X" B: M: m
Polycomb Group Proteins Set the Stage for Early Lineage Commitment
. h/ Z( K/ k- l- z2 ^Lauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer* e0 q' M) ^ T" v1 G
Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
) w" q6 t: P2 B* l0 OMartin Sauvageau, Guy Sauvageau
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Z8 {7 i1 _/ U3 mISSCR: President's Note
4 Z( S z) z$ z% @7 W- NToward a Knowledge of Causes
6 b% `. c. [9 R5 W# }8 Y5 FElaine Fuchs
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) a( v$ o3 Y0 d% m. Z8 h/ ZArticles: |% F, {& w) |
Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
' N1 I6 h5 |) ~3 F1 \* BJian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith
4 H( i1 U* k+ E) L0 d2 @( HFemale Human iPSCs Retain an Inactive X Chromosome' {# r u" v% H
Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath
: h/ M6 M, N; PMyc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells0 y$ E4 K v, v4 b
Keriayn N. Smith, Amar M. Singh, Stephen Dalton
% f/ a: Q& y, H- n! [$ O+ MFunctional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation
% C: p' V& f8 i/ FMirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle+ `( `* a% k& w" U2 b+ P
Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling
! o! F$ h9 T" k% q% A- e8 _, @Sacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas+ @3 t; l9 h5 {, c
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche3 ^3 W8 {7 U1 U8 @, h/ T, ?: v
Tugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek
7 Z7 H) j9 V2 ARegulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells( j9 B" h" @1 H9 a
Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda1 ^3 c9 L$ S/ S5 \1 a2 _' H6 o( a2 \
Featured Article' e) j# n, _; z4 _) b
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells! @( m: d# I7 e+ { G' I
Gemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley; [$ I. N5 p" O7 j5 P- ~
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发表于 2010-9-6 15:44
发表于 2010-9-7 18:30
