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本帖最后由 细胞海洋 于 2010-9-6 20:03 编辑
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7 \( h2 }) U9 D8 a+ w% c' h0 {1 X$ b# O. X& R9 G& ]" J
7 t1 P1 u$ d* M. t3 September, 2010 Volume 7, Issue 3
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Editors' Notes
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/ b/ N5 o* `; H$ j& t. j1 vPreviews
' Y* C- B0 u! O% @Cancer Cell of Origin: Spotlight on Luminal Progenitors# f& i8 \, d# V% Q. p# m
Christine L. Chaffer, Robert A. Weinberg8 O3 v2 I. b2 B* o% O5 a H4 w0 e
Microarraying for Mechanosensivitity
( X& E7 Z ^. E- I! f& h9 rDavid V. Schaffer5 q4 G/ q( Q, Q/ M# Y+ J" L: l
The STATs on Naive iPSC Reprogramming6 e* I) q1 A8 `: K3 [8 R
Jacob H. Hanna
! I1 F2 S2 q3 K+ xHypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword. h) A1 e# J. S$ t0 N
Patrick J. Pollard, Kamil R. Kranc
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Brief Report
2 ~' f" q T9 k0 M q0 |7 YTumor-Initiating Cells Are Rare in Many Human Tumors; G3 w- _; M) H! {8 [5 I
Kota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui
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Forum
6 X4 l5 o7 y0 _( Z( G1 C! b; yThe Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases2 w; W: L+ P- _
Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté
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5 M) {' j/ ]8 N6 [4 Q) XReviews& z2 j$ E4 l& u5 a% m
Polycomb Group Proteins Set the Stage for Early Lineage Commitment6 B8 m" y7 O9 Q6 C! I
Lauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer
# b( l8 d% Q: r' x' YPolycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
- t2 u: X A( w2 p4 y9 l0 b2 CMartin Sauvageau, Guy Sauvageau/ X2 |$ t! w( e# H
! d8 {; x* ~1 D2 F2 Y jISSCR: President's Note) X2 v( b$ ?1 J) p5 T
Toward a Knowledge of Causes
6 b Q3 c7 p$ G- I) {8 U1 x9 \Elaine Fuchs
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Articles7 M( d7 ]5 R1 l* p/ Q% B
Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency) K. r3 r3 t9 `5 d( y0 O" h
Jian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith
+ R* Y6 |" u: P) k* dFemale Human iPSCs Retain an Inactive X Chromosome
8 g* j# R, A! X0 h- `Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath
; I/ L. [9 J4 ]4 t) aMyc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells
9 P6 Z1 _/ p# H/ v8 mKeriayn N. Smith, Amar M. Singh, Stephen Dalton
' ]- I0 h/ p' h% ~' j! h& [Functional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation6 K2 D4 [! e8 I* [
Mirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle( \8 m# t: O) f. H; ]& b) @4 K7 \* Y
Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling
2 {- h- ^5 c, y9 F, z' c7 K/ XSacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas4 h0 D3 q4 T" a+ `6 V' \
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche) U( @! S- O1 J0 H' P; j- J9 s. v' m
Tugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek' ^5 E8 u4 Z! Z+ q
Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
4 ?5 J0 t" }' z" ?Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda
$ @4 @% y, D+ TFeatured Article1 p) L+ f( D% G- B4 ]! c
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
7 B5 H' Z) W/ Y# yGemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley
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