《细胞-干细胞》[Cell Stem Cell]2010年9月3日出版pdf全文

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( P8 Z  M% K/ e3 September, 2010 Volume 7, Issue 32 S0 u& _7 r. ^: U5 A

* ?9 {$ a: q& h- g. ]. v& O( PEditors' Notes0 t5 f2 l! l5 O6 ^

. N6 x; e& f; ~. U9 OPreviews
9 |% X2 T# y/ r  D! ?/ ~9 z! HCancer Cell of Origin: Spotlight on Luminal Progenitors
2 O) Z! _# w9 S: V9 zChristine L. Chaffer, Robert A. Weinberg
8 M/ S# a2 `+ [Microarraying for Mechanosensivitity
1 \% V% ~3 S8 @0 G" X2 w  xDavid V. Schaffer0 {' X, A7 L. w* K) B' d
The STATs on Naive iPSC Reprogramming
& E. w6 P) @( N7 V) V; N3 zJacob H. Hanna- i9 [# Q5 E$ p
Hypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword
7 d1 i/ e6 S& c. {4 u& \; ^, e6 {Patrick J. Pollard, Kamil R. Kranc
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Brief Report7 \2 }: n0 v' m" m1 Z  P1 {
Tumor-Initiating Cells Are Rare in Many Human Tumors
% E9 x3 Y( R, ?' E' hKota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui
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Forum
) t+ ^5 O! Y# D- K/ l' ~0 GThe Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases
! u  A. B: P7 N# \5 g5 iScott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté
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Reviews
( q* ]# o3 Q1 {Polycomb Group Proteins Set the Stage for Early Lineage Commitment; K) D, k' ]) L+ ^
Lauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer; ~: R  V& k( x6 k1 x
Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
: U* ?: I. R1 R1 t" |+ \  wMartin Sauvageau, Guy Sauvageau" x8 H* k, S# }; L0 u

- G! q' F: R/ O* W* JISSCR: President's Note& U+ I5 H1 A/ B7 V9 N
Toward a Knowledge of Causes
: P2 l! P' V! SElaine Fuchs# u- @! ]& i' X4 N; Q" |1 v$ K
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Articles
* {, m* d. k2 R1 g& cStat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency; @0 ~5 e* U8 ^1 j3 u
Jian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith: i+ L  d: T# s3 G: E+ N9 e
Female Human iPSCs Retain an Inactive X Chromosome& ^* K1 g0 N9 ~. n2 Z8 E
Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath! K1 Q) D5 D7 O, @* }+ k4 s
Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells" L7 ]. D% [; L. R2 G, f4 z; T1 ~
Keriayn N. Smith, Amar M. Singh, Stephen Dalton
0 z) n0 r: H0 M/ T8 c0 gFunctional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation
/ c& U. P. j# n8 x* tMirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle
9 T% d; l. u) D: F$ r& ~Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling. m4 P5 k3 m6 X3 D# N% z5 ^
Sacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas
+ x% h" a" w5 R4 D6 R/ Q- MThe Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche1 ?' k$ f! n: w
Tugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek
& I" d" c, Y5 \6 i* }, q- HRegulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells0 r+ ]  _1 n) L  n2 N9 H
Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda1 {5 f% s$ K1 @$ f6 C
Featured Article$ [$ |; m; {# [* r$ \# v3 j
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
5 g+ [, S5 p5 Q) U. A9 MGemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley, T3 F0 w" K5 G, q- y% `& Y
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botizhou

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懵懂干细胞

顶！

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