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本帖最后由 细胞海洋 于 2010-9-6 20:03 编辑
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3 September, 2010 Volume 7, Issue 3
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Editors' Notes
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Previews% S# r# M) T% h
Cancer Cell of Origin: Spotlight on Luminal Progenitors/ D1 A% J. ~# ?/ _
Christine L. Chaffer, Robert A. Weinberg
( ?, `9 a7 k3 X6 V9 B" e& gMicroarraying for Mechanosensivitity
; b# F9 F0 ^3 SDavid V. Schaffer
- _0 k" A: L2 ?$ t7 PThe STATs on Naive iPSC Reprogramming
6 n1 h5 \" m8 D" R }- V VJacob H. Hanna
6 A. x. ]0 z. c$ ]# dHypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword
( ?9 b- w3 c) ^! R) @Patrick J. Pollard, Kamil R. Kranc x4 A6 O9 ?0 `2 d. g/ \
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Brief Report6 i# O/ f. Y$ G+ o
Tumor-Initiating Cells Are Rare in Many Human Tumors. x* d. [0 T3 I
Kota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui
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( W' n g: V- u4 N& u2 R; L" GForum* c, k3 J/ \, G3 p2 y4 G
The Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases. }# x5 _* g( t3 x
Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté% j( V3 R/ i/ U: z; Z* \
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Reviews
6 @4 V8 {3 ~' \. Q1 S# vPolycomb Group Proteins Set the Stage for Early Lineage Commitment$ q: B4 b/ Z; } B( m; y) a
Lauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer
6 N" q2 z, ]9 w2 g: @9 QPolycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
( q; r4 s0 A& DMartin Sauvageau, Guy Sauvageau- L7 g& y4 X% x+ k e4 R
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ISSCR: President's Note0 t" N: Y( p }$ q3 k% ^
Toward a Knowledge of Causes
) D8 c. [( i/ R, P! o+ @: H( jElaine Fuchs6 _; W2 e( T; d) l# V) v
( R. H. u. T7 YArticles) }/ d1 q/ d# [$ H+ c8 E
Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
5 S4 V' F T+ m1 H u$ j6 Y2 b! \ FJian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith4 S) c! a' v# e# u" G
Female Human iPSCs Retain an Inactive X Chromosome% k) I. |. v' i3 U! z$ h
Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath# D' S$ D% X8 v \; E. i5 n
Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells
" [* U: m# g1 L1 f7 z" o0 y: BKeriayn N. Smith, Amar M. Singh, Stephen Dalton
$ B- }, T# L) [4 n+ [Functional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation3 d6 e) E$ |3 G; k
Mirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle2 _+ J7 B0 r; {1 n
Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling9 w4 Y: p4 i& z5 b
Sacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas
8 @$ E9 Y7 z+ X2 f |( BThe Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
) h$ p5 x* a# D; i5 d' |4 A' ?Tugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek* v3 L) P2 T0 k) S7 V; `
Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells0 c- ~7 c$ H8 o) R( B; O
Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda
. g1 K: P, c" `! [4 O& Y; g, z* HFeatured Article
5 Y: S: v) @( P2 b! j8 SBRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
5 j8 J; x# {" Z8 V$ jGemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley
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