《细胞-干细胞》[Cell Stem Cell]2010年9月3日出版pdf全文

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+ x4 D3 {+ s. H" [# f1 ]3 September, 2010 Volume 7, Issue 3
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# a- _. J3 ^- UEditors' Notes+ [( n2 X1 }* \- o/ m$ U
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Previews% ], d2 ?. S( I+ ]% p6 A% T. p
Cancer Cell of Origin: Spotlight on Luminal Progenitors6 @8 S9 F: j) F9 }' F) U$ Z! w  Z
Christine L. Chaffer, Robert A. Weinberg0 A  l% }: J, ~' ~4 u$ V
Microarraying for Mechanosensivitity
1 Z9 `$ K  L0 }; U7 t6 K" U! r# |David V. Schaffer
, ?- v2 y5 X, ?The STATs on Naive iPSC Reprogramming
7 }  X; p8 g. P) nJacob H. Hanna, `% w' D9 o  }- }! a4 d
Hypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword
' W( [- T9 N- O4 m4 GPatrick J. Pollard, Kamil R. Kranc0 d9 A/ f. C; v  M/ p% X

: U8 E. N  Y- h! V, D, o3 S. \5 E! v$ JBrief Report- ^7 d- q4 w" s9 A
Tumor-Initiating Cells Are Rare in Many Human Tumors+ P+ f- i2 E# ]6 Z" B) |# M
Kota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui; ?5 K' s  s% l# ]" q: {
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Forum
8 N1 h+ t, n$ W3 \1 ?3 o9 {3 W/ _2 |4 nThe Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases6 x0 T2 h. x# `2 X. E$ f8 \1 c
Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté% L; n) f! _. c; i

+ P2 z& n# w  }+ B) o# _8 rReviews
7 K5 I3 d4 s, z" `0 q, X1 zPolycomb Group Proteins Set the Stage for Early Lineage Commitment# F) g6 j% `) u
Lauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer
4 \% e' c$ h) V2 \( ^+ w( i6 kPolycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer6 F( e4 @, _, K1 S
Martin Sauvageau, Guy Sauvageau
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ISSCR: President's Note
0 _' ^5 G; _( G8 B; |! BToward a Knowledge of Causes
  a! G9 f# n6 v8 T$ t% X0 S: U' D' B1 sElaine Fuchs- l! {  u6 \9 ^. A
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Articles
0 \! `7 a/ a" a! u+ H) `Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency' Z* h2 |1 B* f, I& _( f1 X/ Q% [8 L
Jian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith  G# j' K$ j- l
Female Human iPSCs Retain an Inactive X Chromosome0 f3 \8 n: t; U
Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath2 K* f  A8 j2 }! P
Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells% Z" N  t/ s9 ]6 W
Keriayn N. Smith, Amar M. Singh, Stephen Dalton. A6 Q3 z  v2 k0 A, Z: H" a
Functional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation
( E9 C- p4 d/ C& Q: rMirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle
4 w3 q) U$ L, z2 o$ M! b( y2 h5 fRegulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling
7 _) T- i  q( y2 w/ LSacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas9 W; ~! G. w# Y$ |; t' s
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
" H4 W- w$ n0 N  {% r# o' X2 i5 ETugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek
' _* r2 c( f/ H7 e9 E7 QRegulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells3 Z) @! q& P) }+ W& U! y
Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda
/ S% G) j. S$ P+ C# v& UFeatured Article* A+ g. [  [4 n( F% q( Q0 b( w# l% S
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells% k0 }5 ]3 ^, K1 n+ x3 L
Gemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley' k- u2 ]1 L5 Q( B' R
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botizhou

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懵懂干细胞

顶！

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