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本帖最后由 细胞海洋 于 2010-9-6 20:03 编辑
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0 _6 N1 e* z0 `, N! c- {! Y. n" D( \ z+ f3 September, 2010 Volume 7, Issue 31 N3 Y" V" x$ m- ]; g
3 y- X( K7 I% m7 i! b! J$ yEditors' Notes
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6 b. f5 x. e" Q1 tPreviews
5 F1 G; a% @' W3 x n) x$ w- CCancer Cell of Origin: Spotlight on Luminal Progenitors
1 W2 G0 l/ Y, [' FChristine L. Chaffer, Robert A. Weinberg
9 R/ g5 h4 [6 ?- L& bMicroarraying for Mechanosensivitity
' ]3 ^. B! d0 ?) MDavid V. Schaffer
2 J) N l( G( W( M7 o8 [The STATs on Naive iPSC Reprogramming
P! k3 U! E* \1 Q5 QJacob H. Hanna( B. d: _% s" @0 F
Hypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword
$ I+ E2 H( v# C8 k6 JPatrick J. Pollard, Kamil R. Kranc
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Brief Report# ~- w" K, a* [' f6 h
Tumor-Initiating Cells Are Rare in Many Human Tumors& y; g7 Q+ ?5 n/ @
Kota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui# c/ k- u9 }2 Y% [5 p4 t+ S( a
' ~6 G! d# j) F) G" }Forum
$ [+ w+ Y% t/ b9 m( L: y: s0 ~The Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases
3 `/ x% `# |5 U4 oScott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté
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Reviews- X, |' s! g6 E" _4 k# f
Polycomb Group Proteins Set the Stage for Early Lineage Commitment4 v1 |/ c* M& ]0 i* S
Lauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer
6 u) I1 R4 b, F- J* j4 [5 q: NPolycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer5 ]! \ a8 z/ P z0 y
Martin Sauvageau, Guy Sauvageau
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& @/ v0 q6 M1 B8 H& O) d0 n" TISSCR: President's Note
# s: y* i8 `: i# x* r3 m: d" O! cToward a Knowledge of Causes
0 y& n7 @& E2 ZElaine Fuchs" ]2 t: J9 P+ e' O; P
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Articles( b/ F9 J; h% I" f" O. u5 i' Q& V
Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency: \) {! ^7 i: ^: M9 a1 ~5 E( ~
Jian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith6 [: v5 Y5 U8 r* G) n+ p, [
Female Human iPSCs Retain an Inactive X Chromosome
8 T( [+ Y+ ?# }Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath% a2 j; ]7 E9 v: l( w
Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells! b$ B1 Y! e% a2 H- d/ e- Z1 I+ \
Keriayn N. Smith, Amar M. Singh, Stephen Dalton5 `" `0 Q" Z. S
Functional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation9 }+ }" ?- m; f; {8 L1 Z, E
Mirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle
0 Y* i. k$ J9 }5 m* x: f& ]Regulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling+ a- i. p# O6 w$ O
Sacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas+ o1 f, u5 ?& M+ a: z
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
5 z0 p- l" ^4 u$ N4 uTugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek, P- t$ e# J% j
Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells9 t' r6 B) B, I" ? ^
Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda
5 m1 O0 P0 n# cFeatured Article
6 d6 }4 p# J9 Y" g9 w6 Z8 i: ~BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells1 A, Z% w2 ] @7 D$ w5 T
Gemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley
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发表于 2010-9-6 15:44
发表于 2010-9-7 18:30
