《细胞-干细胞》[Cell Stem Cell]2010年9月3日出版pdf全文

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3 September, 2010 Volume 7, Issue 3
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# u3 |0 X, R/ h2 j* jEditors' Notes
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% }/ X3 r" G& e: i; n, s# TPreviews
' ~; i1 q: w' K5 N8 m: g3 C& nCancer Cell of Origin: Spotlight on Luminal Progenitors9 g7 Z0 M' n3 b# }0 f2 `
Christine L. Chaffer, Robert A. Weinberg
! n0 \* l2 p2 b1 @) U6 O2 @Microarraying for Mechanosensivitity8 C5 `+ @6 @5 F: Y8 T5 @4 c
David V. Schaffer) Y* E$ y6 D( O
The STATs on Naive iPSC Reprogramming
% X) W) z: h6 p! a$ s# ]' ~. b3 I; |Jacob H. Hanna
- K+ [% ^2 z. C# jHypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword: L. p  t1 H+ w; n
Patrick J. Pollard, Kamil R. Kranc/ q3 d4 D8 p1 `

3 B# r. g. Z5 [7 k# R* F5 U8 `Brief Report( k( |* |# [$ N  l. m# P
Tumor-Initiating Cells Are Rare in Many Human Tumors! S) {3 t' z7 K2 h6 l5 ]9 L6 B
Kota Ishizawa, Zeshaan A. Rasheed, Robert Karisch, Qiuju Wang, Jeanne Kowalski, Erica Susky, Keira Pereira, Christina Karamboulas, Nadeem Moghal, N.V. Rajeshkumar, Manuel Hidalgo, Ming Tsao, Laurie Ailles, Thomas K. Waddell, Anirban Maitra, Benjamin G. Neel, William Matsui7 B- ~9 N7 }$ d$ c
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Forum# T0 }3 H9 ?7 ]
The Orphan Drug Act and the Development of Stem Cell-Based Products for Rare Diseases1 D& n5 v& z# X: e! r6 ~5 L9 r' w8 k, E
Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté  s8 h. E7 u9 a  ]  o

) Z. A3 p" b  s, A8 MReviews
' I- h( x: m' VPolycomb Group Proteins Set the Stage for Early Lineage Commitment( _  I0 M& [) o5 \
Lauren E. Surface, Seraphim R. Thornton, Laurie A. Boyer1 K6 `1 ^2 j: [) {
Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer) [4 l- O+ A( X6 j: L- |2 [* X
Martin Sauvageau, Guy Sauvageau/ J+ k7 {* R3 H2 G4 T" X. S

: F& k3 w; o6 q# W* h" dISSCR: President's Note
/ r7 @9 ~7 }9 y3 `. J; `& D( SToward a Knowledge of Causes
7 {/ h) a& @% z" S5 sElaine Fuchs- h1 l4 g/ A$ N) ?4 T

2 g% u% T, s  ?; x* M: q6 eArticles# x# ], l$ i% m1 x
Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
' J) J5 q: `; v) w* e$ ?) A4 zJian Yang, Anouk L. van Oosten, Thorold W. Theunissen, Ge Guo, Jose C.R. Silva, Austin Smith
& E' m% R  {& [1 q; `Female Human iPSCs Retain an Inactive X Chromosome" I3 @$ ?1 x" I3 {# E! d( R. |) A
Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, Kathrin Plath
9 i. I# A% H9 v, IMyc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells
8 S$ o/ G( y: \* W0 ~0 ^* oKeriayn N. Smith, Amar M. Singh, Stephen Dalton& B) v/ f8 ~. @8 X, I4 r6 n/ f! {0 A
Functional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation
0 ~) _1 Y$ n3 E; F! u2 _Mirza Peljto, Jeremy S. Dasen, Esteban O. Mazzoni, Thomas M. Jessell, Hynek Wichterle
- O" \% S' n( ^) l" ERegulated Segregation of Kinase Dyrk1A during Asymmetric Neural Stem Cell Division Is Critical for EGFR-Mediated Biased Signaling' l& U/ D7 K+ e! G
Sacri R. Ferron, Natividad Pozo, Ariadna Laguna, Sergi Aranda, Eva Porlan, Mireia Moreno, Cristina Fillat, Susana de la Luna, Pilar Sánchez, María L. Arbonés, Isabel Fariñas0 I2 z5 ?$ a0 T
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
, z) K) j, ?; J3 T: U" l& L) a1 v  sTugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J. DeBerardinis, Ahmed I. Mahmoud, Eric N. Olson, Jay W. Schneider, Cheng Cheng Zhang, Hesham A. Sadek
1 }- n# l9 D0 K# hRegulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
" ~2 E% l" L" \( H' L( |9 i2 ^Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S. Johnson, Atsushi Hirao, Makoto Suematsu, Toshio Suda- }( r2 _9 h$ I
Featured Article( U4 H# [6 s* Y2 \
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
8 ]: G$ K2 X0 I" `6 w( K8 e1 TGemma Molyneux, Felipe C. Geyer, Fiona-Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan MacKay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis-Filho, Matthew J. Smalley
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快乐小郎

说的真有道理啊！

chinagalaxy

感觉好像在哪里看过了，汗~  

dd赤焰

顶也～  

天蓝色

干细胞研究人员的天堂

myylove

呵呵,支持一下哈  

apple0

顶你一下.  

小小C

不错，感谢楼主

myylove

21世纪，什么最重要——我！  

hmhy

晕死也不多加点分