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"...that complete erasure of initial identity first takes place, followed by stepwise, unc-3-dependent, redifferentiation into a motoneuron",
; [/ C8 v; E; y. k! r"...reversion to a dedifferentiated identity does not lead to an increase in cellular potential in a natural, in vivo context".
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7 z: a6 x5 N5 v1 j4 p. R这意思是说去分化并不导致多潜能(cellular potential),那么抹去“原身份”后是个什么状态呢?
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哺乳动物体内自然存在的直接转分化机制及其可控性,可能是下一个热点。) z# v! Z0 s+ T% E
8 x2 Z, T* _0 b0 D8 w7 \. w哪位朋友找来原文看看。 |
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