Cell 3月18日 系统生物学特刊

tpwang

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( ~: E5 L, e  k9 @9 i2 s其中有一篇直接与干细胞相关的review：Control of the Embryonic Stem Cell State
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Many of the regulatory features of ESCs probably operate to control cell identity in other cell types. Reprogramming and transdifferentiation experiments support the idea that a small number of master transcription factors can control cell state in various cell types (Graf and Enver, 2009; Vierbuchen et al., 2010; Zhou et al., 2008a). If this model holds true for most cell types, then identification of the master transcription factors of all cell types would significantly improve our understanding of cell identity.. \9 ^* H8 V# k9 B  O6 r

: ^& s+ b. ]  H9 a推断可能存在着控制所有细胞类型的各种状态的“全能主导转录因子（群）”。

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