澳大利亚医生用人工合成血液救活失血患者 属世界首例

sunsong7

来源：国际在线 发布时间：2011-5-6
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据澳大利亚广播公司、澳大利亚新闻网5月5日综合消息，澳大利亚一名妇女出车祸后失血过多生命垂危，被医生用人工合成血液成功救活，属世界首例。
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2010年10月，33岁的澳大利亚妇女塔马拉·科克利发生严重车祸，头骨、肋骨、肘部多处骨折，心肺功能衰竭，脾脏破裂，失血过多，生命垂危。在被送往墨尔本的阿尔弗雷德医院后，医护人员发现科克利是一名“耶和华见证人”的信仰者，这一信仰使得她不能接受输血。当时医生断定，科克利活不过24小时。
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就在这时，该院外伤医生马克·菲茨杰拉德忽然想到使用血液替代品——HBOC-2-1(血红蛋白氧载体)，这是一种利用牛的血浆人工合成的血液替代品，由美国军方研制而成的。菲茨杰拉德医生说：“我们想到使用血液替代品，但只有美国才有，而且只有10个单位。在取得联系后，美国方面把10个单位的产品都给了我们。”在输入了替代血液后，科克利的血红蛋白逐渐上升，她渐渐苏醒，如今已经恢复了健康。7 J9 d0 H0 K$ D# N
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据介绍，菲茨杰拉德医生曾参与了美国的人工合成血液研制，因此对这种产品非常熟悉。他表示，采用人工合成血液救治患者，对于世界性的血液短缺有重要启示。据悉，这种替代血液不需要血型的匹配，不需要冷藏，在常温状态下可以保持3年之久。对于缺乏足够血源的偏远地区而言，这可能是挽救失血患者生命的最佳选择。
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Synthetic blood saves woman's life+ o0 Z8 r; M$ W% ?3 a
Updated Thu May 5, 2011 10:30am AEST ! l8 [1 W; o! A0 D1 l% b7 _
http://www.abc.net.au/news/stories/2011/05/05/3208136.htm
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The synthetic substance is derived from cow's blood. (ABC TV News - file image)$ I$ I! E5 H4 Y; y# m* ^
A doctor who used synthetic blood to save a Victorian woman's life says he is delighted the procedure was successful.* w9 E/ Y- L3 R
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In an Australian first, 33-year-old Tamara Coakley was given a substance derived from cow's blood after she was seriously injured in a car accident.
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6 t  q. j4 i9 @7 [As a Jehovah's Witness, Ms Coakley was unable to have whole blood transfusions but was able to accept substitutes.
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Doctors at the Alfred Hospital sourced the blood from the United States. 6 i- [& p; E, X. E% A- _

/ L# w0 ~3 t( rTrauma doctor Mark Fitzgerald says he tried a number of things to reduce Ms Coakley's blood loss before he thought of using a synthetic product.
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"Probably just after 24 hours after she arrived we knew she wasn't going to survive, and then I started sequentially going through a range of options and this is the one we came up with," he said.0 I) X' E6 f/ ?; w9 i5 }0 `, r
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"At the time we wanted it [the US] only had 10 units available and they gave us all of that product.; k- K- Q# W: B
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"[We were] just unbelievably lucky."0 e) G2 L, I$ J

. B9 g$ k! O% w' W/ {Dr Fitzgerald says the product should be made more readily available in Australia.
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He only knew about the existence of the synthetic blood because he had been involved in trials of the product in the US.
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# F4 O! x$ F: J% r- UHe says it is not a substitute for the real thing, but could go a long way towards addressing blood bank shortages. 9 p3 Y- k5 t, J: u! @# a  K( s
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"Our main interest is to have it available when blood isn't available," he said. ) `: m9 {4 X1 `3 r& n# X. M

; h' R% X6 R4 e"Blood is the number one choice but there are no options after that.
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* e) q+ ]( I6 L& d, F"If you are in a remote area or are isolated, or you don't have access to blood then you don't have any other options."
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9 h7 T% K* @+ v2 R, Y; y7 hTags: health, blood, australia, vic
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, s7 x5 T- }( f+ AFirst posted Thu May 5, 2011 7:56am AEST
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