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我认为将人胚胎干细胞诱导为成骨细胞、成软骨细胞未尝不是一条可能的途径,尽管还存在的许多的问题,但只要我们付出努力,总会有那么一天的。附上我们实验室去年发表的一篇关于ES向软骨样组织诱导的paper。
* b, P0 Q& F3 f/ Q/ y! JBai Hai Yan, Chen Gui An, Mao Gen Hong, Song Tian Ran, Wang Yan Xia. Three step derivation of cartilage like tissue from human embryonic tem cells by 2D-3D sequential culture in vitro and further implantation in vivo on alginate/PLGA scaffolds. Journal of biomedical materials research Part A, 2010, 94(2): 539-546. |
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