stem cell news 110603-08

kittybruce

Voice from last issue:. m& Y& L. u8 z
. E" E% T7 B6 V( w
"The normal concept is by giving these cells of blood vessel origin, we hope to both create new blood vessels in the expansion of those implanted cells or promote the center to regenerate new blood vessels in the cells that reside in it. It’s not entirely distinct regardless of whether it can be the true cell alone that may do that or regardless of whether it can be just the milieu along with the chemical indicators that arise in the cells that may consequence during this."-- Carl J. Pepine, M.D., chief of cardiovascular medication at UF’s higher education of medication.
9 x; H, Q; R  v7 ]# g5 q
& s5 L2 J. ^- o, v# s"After implantation, these stem-cell derived cells are effectively growing into human cells of the pancreas, the organ which produces insulin."--John West president of San Diego based company ViaCyte Inc.
. Q3 [/ P* \) m7 M  o" M( Y  V) A2 u- M0 |0 e/ `
“The study results of Advanced Cell Technology (ACT)’s RPE cells implanted in the various animal models of macular degeneration was phenomenal. If ACT observes even a fraction of that benefit in humans, it will be nothing short of a home run.”--Raymond Lund, Ph.D., a scientific collaborator with ACT.
% i8 r0 m$ M. s/ g$ }4 c' d* h
: x6 ~0 g3 ~- m"My greatest regret is that someday there will be people who will benefit from stem cell therapies, but who will never know the sacrifices that Bill and his wife Nancy made for their well-being."--Dr. Robert Lanza, M.D., Chief Scientific Officer at Advanced Cell Technology.
3 ~: s6 l0 g( T  i- U2 s- P1 n# k. ?1 ]3 C# d# p5 J; h$ o- a1 J
“Unfortunately, there are many loopholes in FDA regulations...Lots of patients have been harmed, by otherwise well-intentioned but misinformed practitioners.”--George Daley, director of stem-cell transplantation research at Children’s Hospital in Boston.
$ V+ w8 X# w1 m* W7 b
0 I1 E* y" x5 w- f" J- d“Looking at how a single cancer cell behaves if it’s transplanted into a mouse won’t necessarily tell you what it does in its natural environment. We don’t know whether the cells that cause cancer in a mouse are the ones that cause patients to relapse.”--Kornelia Polyak at Dana-Farber Cancer Institute.) M: L* K% R- a% z

/ G4 N* v" C* Z“If cancer stem cells turn out not to be rare, and if they’re reversible, do you gain anything from being able to identify them? Then you’re no longer looking for a needle in a haystack—it’s a haystack in a haystack. If there’s no hierarchy, we’re back to where we started. We have to kill all the cancer cells after all...The history of cancer biology is littered with dashed hopes following breathless predictions about how this discovery or that paradigm shift will lead to widespread cures. Cancer is endlessly resourceful. That’s why none of these latest things—including the cancer- stem-cell model—turns out to be the whole answer.”-- Sean Morrison.; }- I3 M4 |5 {9 a$ }
5 r7 Z- `( A# n  u
“We actively and directly induced one cell type to become a completely different cell type. These are fully functional neurons. They can do all the principal things that neurons in the brain do. That includes making connections with and signaling to other nerve cells...We were very surprised by both the timing and the efficiency. This is much more straightforward than going through iPS cells, and it’s likely to be a very viable alternative. That means reprogramming doesn’t only go backward, but can occur in any direction. If you extrapolate from this, you could* E# C- O  c  t2 \0 }, ?3 y5 Y2 x
probably turn any cell in your body into any other cell if you just know the right factors.”--Marius Wernig from Stanford.8 Z+ y( r9 \- G* ~
3 M5 T% t5 V- I  Z1 L& G. j+ h
* b' h  ], r( ~$ M8 U. k1 Z: ^; @. g. c
This issue:
1 i6 }! ]3 u7 j; ~6 g4 w
1 L) _" o) ^0 W5 [* y
0 i6 P3 b& K' X1 U
$ f( u& c- M4 u% oVideo news:
" B, Y/ r% [7 g" z8 }& gAn Alabama man undergoes stem cell therapy for paralysis4 y3 Z* c9 v$ q
http://www.abc3340.com/story/148 ... erapy-for-paralysis7 G' u5 }5 \  j, I* V6 c

7 h  l$ _. `& [6 O0 {Stem cells save legs( ^; }) q* ?8 c) L
http://www.fox23news.com/content ... rE-wGivEKna92w.cspx

qmm0303@163.com

After implantation, these stem-cell derived cells are effectively growing into human cells of the pancreas, the organ which produces insulin
8 _0 N. G7 _7 M8 Q3 O' F! d干细胞临床转化还是很有前景的，为了人类的健康，生命的延续，干细胞研究人员们加油吧！