Cell Fate Plug and Play: Direct Reprogramming and Induced Pluripotency

pla269

Building on the discovery that MyoD expression reprograms fibroblasts into muscle, three papers
: K4 n9 G) c2 W- v3 U* P9 }3 B' u5 F(Vierbuchen et al., 2010; Ieda et al., 2010; Szabo et al., 2010) recently reported the reprogramming of' B3 X6 r* q8 s2 q0 o+ l8 u* d5 ]0 H* N
fibroblasts into neurons, cardiomyocytes, and blood cell progenitors without first passing the cells
- O* A. l% y; Kthrough a pluripotent state. Here we discuss the advantages and challenges of harnessing this
, s( e/ G& F% M" O5 n' H/ x. }direct reprogramming method for regenerative medicine.

jhu132llh

还是各有所长吧3 A# p* A% N1 q: X
IPS虽然有很多的缺陷
: H) m3 ]& u" B# j5 k! _  I) m但是也不是就能断定以后就没有人能攻克这些个问题9 d) ?) N/ s: R

张也行

谢谢分享