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本帖最后由 细胞海洋 于 2011-7-29 23:42 编辑 " S: O) M3 B8 g& f: H( U
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干细胞研究的百科全书,不敢独享~stem cell? We have a basic working definition,
8 y) v! y& ^! O0 f3 a3 Tbut the way we observe a stem cell function& c) G+ ]! ^& J q( h
in a dish may not represent how it functions in aliving organism. Only this is clear: Stem cells are
7 ~2 ]2 g3 T3 |$ o) I9 n, Lthe engine room of multicelluar organisms for both; K. V* D# V) S# q3 ^% Y* d8 q$ a
plants and animals. They live in cave-like “niches,”
3 A! p( ]/ |) ~( G- fsurrounded by intricate signals that allow them to
. [7 ?" a1 J; O$ |5 Rdivide—either to make more of themselves (selfrenew),
" \# l. y6 J0 Q" [! g. xor to produce a progeny that can go on
# s4 R6 M' f" vto make a specific type of tissue. They can often- N+ o% e a% S% T$ Z+ }
be plucked from this environment and placed in+ Q. l0 T) I" o2 R
a nutrient broth at body temperature and encouraged
; u/ W% `( w ]2 `# @1 wto divide, although the niche is generally lost
$ q/ _6 z" v7 _: Pand their characteristics often change.
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