本帖最后由 hongjie88 于 2011-8-7 22:34 编辑 $ J! o! A& L0 N0 e/ a+ }
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我看最近有好多关于这个的文章啊，貌似是很火& r$ N1 Y9 S: e0 f0 C/ v8 z
列几个跟大家分享一下 + e2 f F9 q* e7 q" [Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.Cell Stem Cell. 2011 Aug 5; 9(2): 166-75 X w+ x- g" y; A* {# V8 B$ f
Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.Cell Res. 2011 Jul 12/ T1 ~, ^! K& w8 Z E5 e
Tissue specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genome.J Biol Chem. 2011 May 24 2 D9 G2 \ h. Q, q6 z1 AGenome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.Nature. 2011 May 8; * @2 R6 q9 m$ {( R
Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells.Mol Cell. 2011 Apr 20; 9 [$ f$ u5 v+ J/ l' I) e+ [$ _
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.Nature. 2011 Apr 3; 3 ?4 S2 ?' j: F% i& }3 Y3 N" T
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.Genes Dev. 2011 Apr 1; 25(7): 679-84" [7 f) o. i5 H# |- H
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.Nature. 2011 Mar 30; ' l% F2 Q9 o2 l: c) x$ s- X! a
Tet1 and tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.Cell Stem Cell. 2011 Feb 4; 8(2): 200-13 & W0 V4 K X5 f这才半年就有这么多文章。。。8 @2 h0 w$ @% u& k" J
大家感兴趣的交流一下吧2 @% x5 {( s0 _
我在一篇文章里面看到Ayu17-449, a novel gene on mouse chromosome 3, was identified by the gene trapping technique previously reported by Tang et al. (2006). In NCBI database analysis, Ayu17-449 is also called TET-2 (tet oncogene family member 2). It belongs to a novel, well-conserved, protein family but with unclear biological function, the TET protein family, including three members (TET-1, TET-2 and TET-3). 不知道这tet2是不是Ayu17-449
我这里也有几篇，供大家参考 " P3 _) |$ E+ l: z6 p+ {/ c; DTET Genes: new players in DNA demethylation and important determinants for stemness, Experimental Hematology 2011;39:272–281! q6 C% v' z) O, b" a5 @ b
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity,1 9 M AY 2 0 1 1 | VO L 4 7 3 | N AT U R E | 3 4 3. o3 ]) o H! \/ Q0 B) ?
Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine 3 V }5 w0 { F% G4 U, u# NThe role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
好像缺几篇文献吧. d2 v3 |! v9 _2 I; m& x6 U
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Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.Cell Stem Cell. 2011 Aug 5; 9(2): 166-75$ b) a% o J j; c9 B
Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells.Mol Cell. 2011 Apr 20;, T# n6 A s$ j- B. |3 H/ @
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.Genes Dev. 2011 Apr 1; 25(7): 679-84" ~% M( V) z: w# V- m( b
都没有啊 % o" a5 j8 U: D! ~+ m1 n版主，你有没？: U4 N2 j' ^" f5 h! H' V, }
或者群友别人有没》？
发表于 2011-8-7 22:17
发表于 2011-8-7 23:49
