| Slide No. | Slide Titles | 
| Launch Pathway |
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| back to top | APOPTOSIS AND CELL CYCLE | |
| 1 | Programmed Cell Death | |
| 2 | Activation and Inhibition of Apoptosis | |
| 3 | Mitochondria in Apoptosis | |
| 4 | ATM/p53 Signaling Pathway |  |
| 5 | Caspase Cascade |  |
| 6 | Caspase Activation Intrinsic Pathway | |
| 7 | Granzyme B | |
| 8 | Fas and Related Proteins with Death Domains | |
| 9 | Fas Signaling Pathway | |
| 10 | G1 and S Phases of the Cell Cycle | |
| 11 | G2 and M Phases of the Cell Cycle | |
| 12 | Regulatory Cascade of Cyclin Gene Expression | |
| 13 | The p53 Signaling Pathway |  |
| back to top | CYTOKINES, GROWTH FACTORS AND HORMONES | |
| 14 | Cytokines, Growth Factors and Hormones | |
| 15 | Structures of Activin and Inhibin Prototypes and Precursors | |
| 16 | Structures of Three Chemokine Receptors | |
| 17 | Angiopoietins and their receptors, Tie1 and Tie2 | |
| 18 | EGF Receptor Signal Transduction Pathway |  |
| 19 | Transmembrane Precursors of EGF Family Members | |
| 20 | Possible Receptor Combinations and Ligand–binding with EGF and HGF Families | |
| 21 | Actions of Flt-3/Flk-2 Ligand on B Cell Lymphopoiesis in Bone Marrow |  |
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| 23 | IGF Regulation of Apoptosis | |
| 24 | IL-13 and IL-4 receptor combinations and binding | |
| 25 | IL-18 Production and Role in Immune Response | |
| 26 | Neurotrophins and Their Receptors | |
| 27 | TrkA Receptor | |
| 28 | GDNF Family with Receptors | |
| 29 | PDGF Receptors and Actions | |
| 30 | Signaling Pathway of TGF-b | |
| 31 | Bone Morphogenic Protein | |
| 32 | TNF Signaling Pathway | |
| 33 | TNF-α and TNF-β (LT) Forms and Receptor Binding | |
| 34 | Proposed Balance Between TNF Superfamily Members in Relation to Bone Formation or Destruction | |
| 35 | Structure of Receptors and Growth Factors Involved in Vasculogenesis, Angiogenesis and Lymphomagenesis | |
| 36 | VEGF Receptor and Ligands | |
| 37 | Signal Transduction Pathways Involved in Prolactin Regulation | |
| 38 | Insulin Pathway | |
| 39 | Glucocorticoid Receptor Signaling | |
| back to top | CYTOSKELETON AND EXTRACELLULAR MATRIX | |
| 40 | Vascular Endothelial Cell Interactions and Signaling | |
| 41 | Integrin Signaling in Cell Survival and Death | |
| 42 | VEGF Receptor Signaling | |
| 43 | The MMP/Cytokine Connection | |
| 44 | Events Leading to Angiogenesis and Metastasis | |
| back to top | GENE REGULATION AND EXPRESSION | |
| 45 | Transcription Factor Regulation (CREB, Elk-1 and c-Fos) | |
| 46 | Hormonal Targeting of Nuclear Complexes to Chromatin | |
| 47 | The Jak/Stat Signaling Pathway | |
| 48 | STAT3 Signaling Pathway | |
| 49 | PPAR Signaling Pathway | |
| 50 | Formation of Nucleosomes | |
| 51 | DNA Compaction into Chromosomes | |
| 52 | Early Response Events to Moderate Double Strand Break (DSB) Levels | |
| 53 | Cell Cycle Checkpoint and Double Strand Breaks (DSB) | |
| 54 | Linkage Between DNA Repair and Chromatin Modification | |
| 55 | Hypothetical Model on the Functions of the WRN, BLM and MRE11 | |
| 56 | mRNP Transport through the Nuclear Pore Complex (NPC) | |
| 57 | Cargo Import by the Importinα-Importinβ Pathway | |
| 58 | Modular Structure of Transcription Factors | |
| 59 | Transcription Activation by Nuclear Receptors | |
| 60 | Coupled RNA Splicing and Nuclear Export | |
| 61 | RNA Polyadenylation | |
| 62 | Mammalian mRNA Polyadenylation Machinery | |
| 63 | RNA Maturation | |
| 64 | RNA-guided Epigenetic Control of Gene Expression | |
| 65 | Phosphorylation-driven Regulatory Switch from Transcription Initiation to Elongation | |
| back to top | G PROTEINS AND CYCLIC NUCLEOTIDES | |
| 66 | Cyclic Nucleotide Metabolism - cAMP | |
| 67 | Cyclic Nucleotide Metabolism - cGMP | + v; s1 | P# @$ J y( E5 N- b$ u9 A
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| 68 | Diversity of G-Protein-Coupled Receptor Signal Transduction Pathways | |
| back to top | IMMUNE CELL SIGNALING AND BLOOD | |
| 69 | T Cell Receptor (TCR) Signaling |  |
| 70 | B Cell Receptor Complexes | |
| back to top | ION CHANNELS | |
| 71 | Monovalent Ion Channels | |
| 72 | Activation and Inactivation of the Sodium Channel | |
| 73 | Ligand-Gated Ion Channel: Structure and Activation Status | |
| 74 | Aquaporin Channel Structure | |
| 75 | Calcium Channel Structure | |
| 76 | Calcium Channel Pore Region | |
| 77 | Schematic Representation of the Chloride (CIC) Channel | |
| 78 | Schematic Representation of the HCN Channel | |
| 79 | 2TM Potassium Channel Structure | |
| 80 | 6TM Potassium Channel Structure | |
| 81 | Sodium Channel Structure | |
| 82 | Sodium Channel Pore Region | |
| back to top | LIPIDS IN CELL SIGNALING | |
| 83 | PTEN Pathway | |
| 84 | Lipids in Cell Signaling | |
| 85 | Inositol Phosphates | |
| 86 | Phosphatidic Acid Synthesis | |
| 87 | Signaling by Inositol Phospholipids | |
| back to top | MULTI-DRUG RESISTANCE | |
| 88 | Mechanisms In Multi-drug Resistance: ABC-transporters and detoxification enzymes I hepatocytes | |
| 89 | ABC-ATPases as Regulatory Transporters for NHRs: chemical sensors for endogenous metabolites and xenobiotics | |
| 90 | Domain Organization of Bile Salt Transporter (BSEP) | |
| 91 | Domain Organization of Multi-drug Related Protein (MRP1) | |
| back to top | NEUROBIOLOGY | |
| 92 | b-Amyloid Plaques | |
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| back to top | NEUROTRANSMISSION | |
| 94 | Second Messenger Systems Involved in Reward and Addiction | |
| 95 | Limbic Reward Circuit | |
| 96 | Major Noradrenergic, Dopaminergic and Serotonergic Pathways in the CNS | |
| 97 | Intracellular Signaling Pathways Activated by Endothelins | |
| 98 | NPY Inhibition of Catecholamine Release | |
| 99 | Ascending Pain Pathway | |
| 100 | Modulation of Pain Transmission | |
| 101 | Mechanism of Action of Selective Monoaminergic Reuptake Inhibitors. Figure A | |
| 102 | Mechanism of Action of Selective Monoaminergic Reuptake Inhibitors. Figure B | |
| 103 | Drug Activation of Dopaminergic Neurons | |
| 104 | Schematic Representation of the GABAB Receptor | |
| back to top | NITRIC OXIDE AND CELL STRESS | |
| 105 | Oxidative Stress | |
| 106 | Neuronal Nitric Oxide Synthase (nNOS) | |
| 107 | Endothelial Nitric Oxide Synthase (eNOS) | |
| 108 | Inducible Nitric Oxide Synthase (iNOS) | |
| 109 | Nitric Oxide Metabolism | |
| 110 | Proteasome/Ubiquitination | |
| 111 | Formation of Activated 20S Proteasome | |
| 112 | Ubiquitin-Proteasome Pathway | |
| back to top | PROTEIN PHOSPHORYLATION | |
| 113 | Mitogen-activated Protein Kinase Cascades | / t4 g3 N) Z! v5 P4 ^& b
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| 114 | Akt Signaling | 7 B. f* R, M1 i" ~0 ?5 Q
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| 115 | Signaling Pathways Activated by VEGF |
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