间质细胞(包括成纤维细胞和肌成纤维细胞)在TNF过表达小鼠CD样IBD模型中是TNF致病的主要靶点。 1 ~. c9 e" b0 m, u u4 h& \Armaka M, Apostolaki M, Jacques P, et al. Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases. J Exp Med 2008;205:331-7.
Armaka M, Apostolaki M, Jacques P, et al. Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases. J Exp Med 2008;205:331-7.