PDF电子书：PROTEIN KINASES （2012）

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PROTEIN KINASES$ ]; v- M0 Z1 _3 ?5 q
Edited by Gabriela Da Silva Xavier8 X% {4 O7 q5 y
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Copyright © 2012 InTech0 R; m: G4 x3 G

, C& g/ Q0 n/ XContents/ v+ \3 g; ~  V3 Z2 U
Preface   IX8 V9 U$ S: f6 M, I7 _
Chapter 1     The Target of Rapamycin: Structure and Functions    1
% K$ b# l/ Z: Z2 DChang-Chih Wu, Po-Chien Chou and Estela Jacinto
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Chapter 2     SNF1/AMP-Activated Protein Kinases: Genes, Expression and Biological Role   410 y! k5 [0 C* S+ R( W9 ?( f7 M% v. ~
Dmytro O. Minchenko and Oleksandr H. Minchenko" a# }' b' A* i5 P

1 t& e5 m3 }7 lChapter 3   Alternating Phosphorylation with O-GlcNAc Modification: Another Way to Control Protein
% a, C' }- y6 R; Y3 R6 n. _% pFunction   63
* h5 ^# v8 s5 v( A% Z4 gVictor V. Lima and Rita C. Tostes" `# h8 o0 \8 w' }

9 }" r; k1 h& g1 QChapter 4     Technologies for the Use of Protein Kinases into Medical Applications    79 Yoshiki
2 ^0 s# Y$ ^1 p& z5 H' {2 EKatayama
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# Y. t0 Q* a* A# V! aChapter 5   Role of Kinases and Phosphatases in Host-Pathogen Interactions 99 Horacio Bach
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Chapter 6   Pathogen Strategies to Evade Innate Immune Response: A Signaling Point of View   123
! G% g& S% v- v" T5 e1 YBruno Miguel Neves, Maria Celeste Lopes and Maria Teresa Cruz( o0 s; x* U$ N+ v( h2 j
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Chapter 7 Phosphorylation-Regulated Cell Surface Expression of Membrane Proteins 165 Yukari Okamoto ' n6 P6 M5 P$ {/ k4 a3 l& j
and Sojin Shikano! g8 l; b) O% q: l! J
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Chapter 8   Regulation of Retrotransposition of Long Interspersed Element-13 ]# F7 ~7 V' r) a/ W# ~# |
by Mitogen-Activated Protein Kinases   187- E8 O) F4 P( ^8 r7 p
Yukihito Ishizaka, Noriyuki Okudaira and Tadashi Okamura" Q, x8 {$ s% x- Q+ R9 V

3 a1 e% Q9 U; k2 k' n7 DChapter 9    Connexins as Substrates for Protein Kinases and Phosphoprotein Phosphatases    199# u: H( s2 k& v8 Q5 k
José L. Vega, Elizabeth Baeza, Viviana M. Berthoud and Juan C. Sáez8 F: z4 H. v, L
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VI     Contents
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. w* k* [1 ~  G/ {0 m& TChapter 10     Protein Phosphatases Drive Mitotic Exit    215
' W; C! v# q# \# I6 s4 C! R4 eMegan Chircop
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Chapter 11   Regulations and Functions of ICK/MAK/MOK – A Novel MAPK-Related Kinase Family Linked
2 c$ }6 Q+ s1 D0 Y" y- Yto Human Diseases  229 Zheng “John” Fu  C- N# _( N. ^' h
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Chapter 12     Protein Kinases and Protein Phosphatases
( Y% `0 P: e4 W% ?, Zas Participants in Signal Transduction of Erythrocytes    249
" G; B& q9 s6 kAna Maneva and Lilia Maneva-Radicheva, {1 K- F+ J5 M. x3 t8 L) J& `. x

$ s1 V$ c8 V4 y% W2 @; c! t) aChapter 13    Role of Protein Kinase Network in
9 t1 |) J7 P! L$ r+ AExcitation-Contraction Coupling in Smooth Muscle Cell    2876 s1 R) a' p4 z/ y5 g4 f
Etienne Roux, Prisca Mbikou and Ales Fajmut* O$ X3 W* k+ B$ S6 h
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Chapter 14    Regulation of Na+/H+ Exchanger Isoform 3
) D: b' e! W1 `1 s, D( n/ uby Protein Kinase A in the Renal Proximal Tubule   3216 _& a8 d5 K  d% n, L/ L
Adriana Castello Costa Girardi and Luciene Regina Carraro-Lacroix
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Chapter 15     cGMP-Dependent Protein Kinase
' {9 I  p0 Z0 s4 O) w* Nin the Regulation of Cardiovascular Functions  337
5 h! k: ]: e, r2 L) J# CYuansheng Gao, Dou Dou, Xue Qin, Hui Qi and Lei Ying
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Chapter 16    The Crucial Role of c-Src
% r: Y& U7 e9 a' N: D+ C3 ^Tyrosine Kinase in Bone Metabolism    3575 |0 d. S' [6 b% `* ?0 D
Barbara Peruzzi, Nadia Rucci and Anna Teti5 x; ~) f5 I5 E
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Chapter 17     The ERK MAPK Pathway7 ?) U3 D. u' v. ]; E+ e
in Bone and Cartilage Formation   381% |6 a9 E& S5 ?: g  ~
Takehiko Matsushita and Shunichi Murakami/ ^5 L' A& P2 C: O
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Chapter 18     Protein Kinases and Pancreatic Islet Function    399
+ ~! b. r" F0 L2 `$ y! z9 _Gabriela Da Silva Xavier, ~' m7 L( x; \1 l* [9 a
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Chapter 19   Raf Serine/Threonine Protein Kinases:6 _( x1 u! k7 _, U, H6 d( q
Immunohistochemical  Localization
* b+ s# K3 E; X: ?5 n- c. A6 Zin the Mammalian Nervous System   4232 Y# n/ |; I9 {6 j. k2 `
András Mihály0 @4 G# v6 u7 F& e. w3 v7 Z

, k+ l$ s$ Z( Q, O8 M' [8 l* q0 bChapter 20     Protein Kinases in Spinal Plasticity:: {; O: e( h% ]8 O9 y4 Y9 D$ p( f
A Role for Metabotropic Glutamate Receptors   4435 Q- c4 S9 r$ O/ ~6 E* x: n7 R
J. Russell Huie and Adam R. Ferguson2 u# i5 [; g) ]/ N, _4 a/ F9 Q
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Chapter 21     Protein Kinases and Pain    459
) G" |* ^. ~% W8 Z& ^Mani Indiana Funez, Fabiane Hiratsuka Veiga de Souza,9 I& @0 H, V9 [
José Eduardo Pandossio( t, C$ [, X2 J& ?. ?$ b) ^
and Paulo Gustavo Barboni Dantas Nascimento
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