PDF电子书：PROTEIN KINASES （2012）

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' _5 G4 H1 a! }/ j- aPROTEIN KINASES' s8 W1 T! t, l' Q( T& N0 I+ Y
Edited by Gabriela Da Silva Xavier
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8 |4 E# X+ m; KCopyright © 2012 InTech
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# M& s& A3 e% s5 G' AContents
0 {8 w9 k5 b8 m2 S8 W" |, GPreface   IX
) M0 V* X; \  W- s1 S( q7 `" J5 tChapter 1     The Target of Rapamycin: Structure and Functions    1
4 x( l3 B/ M  g% cChang-Chih Wu, Po-Chien Chou and Estela Jacinto
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Chapter 2     SNF1/AMP-Activated Protein Kinases: Genes, Expression and Biological Role   41$ ^& V3 U# r$ J: \7 h
Dmytro O. Minchenko and Oleksandr H. Minchenko
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Chapter 3   Alternating Phosphorylation with O-GlcNAc Modification: Another Way to Control Protein 2 e8 g6 X" ~$ U. G1 {3 j5 i' J% v) _
Function   63# b# E7 N: P) s
Victor V. Lima and Rita C. Tostes" H' g5 H. q7 Q0 s

- _  E& A: R7 K# l! V4 }& a1 J, \- lChapter 4     Technologies for the Use of Protein Kinases into Medical Applications    79 Yoshiki
/ u4 F( X) A" H2 x5 JKatayama
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Chapter 5   Role of Kinases and Phosphatases in Host-Pathogen Interactions 99 Horacio Bach
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7 [+ k' K  j# v/ z, v6 }Chapter 6   Pathogen Strategies to Evade Innate Immune Response: A Signaling Point of View   123
) L* d3 D' N$ C# R8 W4 ~6 d4 yBruno Miguel Neves, Maria Celeste Lopes and Maria Teresa Cruz3 Q: I2 [, t) P/ q$ v

2 ]$ _9 E7 j5 X9 _' z. A  XChapter 7 Phosphorylation-Regulated Cell Surface Expression of Membrane Proteins 165 Yukari Okamoto
' V# m1 R& z3 b2 ?0 u! land Sojin Shikano1 u5 F! J* z1 \9 U" ?
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Chapter 8   Regulation of Retrotransposition of Long Interspersed Element-15 b' J0 T1 u$ S% x- Y" u, i
by Mitogen-Activated Protein Kinases   187
' _8 ]/ a: V1 N, b* wYukihito Ishizaka, Noriyuki Okudaira and Tadashi Okamura1 t$ O1 s) O8 s7 N) i9 @. R# ?- a$ y
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Chapter 9    Connexins as Substrates for Protein Kinases and Phosphoprotein Phosphatases    199
# O8 p5 |9 Z; o* O" {José L. Vega, Elizabeth Baeza, Viviana M. Berthoud and Juan C. Sáez8 R! Q8 t* U# y" L

) o6 C9 H" J; Z4 C3 K' LVI     Contents
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Chapter 10     Protein Phosphatases Drive Mitotic Exit    2157 ^6 a1 g) ]  I6 N* U# X: k
Megan Chircop2 O1 \# J; T3 u: T
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Chapter 11   Regulations and Functions of ICK/MAK/MOK – A Novel MAPK-Related Kinase Family Linked 0 r* X$ P& A( U0 {& s: _
to Human Diseases  229 Zheng “John” Fu5 o6 ~: F! t5 |, j- y" E3 _
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Chapter 12     Protein Kinases and Protein Phosphatases9 y, X# r6 ~/ e* o  m
as Participants in Signal Transduction of Erythrocytes    249
3 j8 ~" A  ?# T! kAna Maneva and Lilia Maneva-Radicheva
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Chapter 13    Role of Protein Kinase Network in
8 e  M: V3 C, D0 B' E1 SExcitation-Contraction Coupling in Smooth Muscle Cell    287
+ e- \! s$ J1 w2 ~! a3 uEtienne Roux, Prisca Mbikou and Ales Fajmut5 z8 Z: u. ?6 j, [+ {; e" O
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Chapter 14    Regulation of Na+/H+ Exchanger Isoform 3% j$ b3 U7 F, y; H* E
by Protein Kinase A in the Renal Proximal Tubule   321, h! L  D# ]* ~+ k
Adriana Castello Costa Girardi and Luciene Regina Carraro-Lacroix
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Chapter 15     cGMP-Dependent Protein Kinase: B3 w" |+ R. W- n6 Y7 a8 g  V7 O3 u/ E
in the Regulation of Cardiovascular Functions  337
, M% F0 V+ e1 j/ \Yuansheng Gao, Dou Dou, Xue Qin, Hui Qi and Lei Ying# N, U* o0 k* A% m- h
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Chapter 16    The Crucial Role of c-Src
7 _$ ]" {$ Y: R& ~1 s4 Z( |" pTyrosine Kinase in Bone Metabolism    357
+ }$ R! O1 k9 b& Y2 r5 X* wBarbara Peruzzi, Nadia Rucci and Anna Teti6 v: e% J: [3 N. A) {3 ?

% V5 k1 e! b# ^) zChapter 17     The ERK MAPK Pathway# B4 v  [6 W' H, H4 O
in Bone and Cartilage Formation   381
0 e( G6 q8 I  e! L4 f4 WTakehiko Matsushita and Shunichi Murakami
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) m) s7 b$ `1 d5 R" HChapter 18     Protein Kinases and Pancreatic Islet Function    399
$ u( y3 T  D. C( @! o* |6 I. o* NGabriela Da Silva Xavier
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. F/ p1 I6 ]- p- j0 U# uChapter 19   Raf Serine/Threonine Protein Kinases:
* Z4 C) R& k3 C$ VImmunohistochemical  Localization! L- }5 y/ x! R# E" `) L- U: G  q
in the Mammalian Nervous System   423
+ \/ |3 v5 z# _3 dAndrás Mihály# `7 ^- }/ G/ s/ }0 q- m

: [+ B9 o5 i5 S& {9 k3 M8 [; IChapter 20     Protein Kinases in Spinal Plasticity:' H5 z2 R4 W6 B& M' x! V" ]
A Role for Metabotropic Glutamate Receptors   443- s; V5 I6 J8 C
J. Russell Huie and Adam R. Ferguson0 w7 E) _3 W, m; t/ C& ]/ d2 ?

( e: K5 K# |- I" h2 BChapter 21     Protein Kinases and Pain    4597 x; v9 s8 Q) u+ k; G+ w
Mani Indiana Funez, Fabiane Hiratsuka Veiga de Souza,. S. Z3 ^  X2 }0 a1 l
José Eduardo Pandossio7 e* D0 P  D+ c* j2 }, P& Q. G" P
and Paulo Gustavo Barboni Dantas Nascimento4 U5 v$ N% z$ [5 p4 e8 b. u" ?

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