PDF电子书：PROTEIN KINASES （2012）

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% t* F- U1 r6 j( t' N+ [PROTEIN KINASES
$ W0 ^, f9 H" F  U1 }Edited by Gabriela Da Silva Xavier8 F: ]5 s' g' H9 d& b
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Copyright © 2012 InTech
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Contents
$ m9 {7 i! k# o  E1 K+ [Preface   IX" F- O! ~- q! Q' _$ S# K% m. K
Chapter 1     The Target of Rapamycin: Structure and Functions    1
) e# K% B2 r; Q0 W1 o- ^Chang-Chih Wu, Po-Chien Chou and Estela Jacinto
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9 g- ?" F% N6 i7 W' I- S1 lChapter 2     SNF1/AMP-Activated Protein Kinases: Genes, Expression and Biological Role   418 p0 p2 r3 P, f6 X0 I; Z
Dmytro O. Minchenko and Oleksandr H. Minchenko) b% n. |* Y- U

3 K/ g' Y" T0 o* SChapter 3   Alternating Phosphorylation with O-GlcNAc Modification: Another Way to Control Protein
- Z. a) H# ]( ]) `Function   63
8 a. E# u% O% `. K  b" _, i2 W/ SVictor V. Lima and Rita C. Tostes
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Chapter 4     Technologies for the Use of Protein Kinases into Medical Applications    79 Yoshiki ' l! X/ K- H6 Q7 W
Katayama, {1 m% G' W7 b

$ I4 ~% Z, S% `Chapter 5   Role of Kinases and Phosphatases in Host-Pathogen Interactions 99 Horacio Bach* _6 s9 K# e4 e0 J  Q  n* [
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Chapter 6   Pathogen Strategies to Evade Innate Immune Response: A Signaling Point of View   123
' F: k' B% B) E/ xBruno Miguel Neves, Maria Celeste Lopes and Maria Teresa Cruz
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Chapter 7 Phosphorylation-Regulated Cell Surface Expression of Membrane Proteins 165 Yukari Okamoto
* f' p' s* {  h2 d0 a: e( cand Sojin Shikano
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8 U; H& X1 |! T! N# ~8 T/ zChapter 8   Regulation of Retrotransposition of Long Interspersed Element-1* w+ W/ O8 E9 X, w% Y
by Mitogen-Activated Protein Kinases   187  Y5 w. }5 G3 H' ~6 ?
Yukihito Ishizaka, Noriyuki Okudaira and Tadashi Okamura& R( ?: Q- {6 y& i, p3 U$ h- P# l

! r. F3 z# `1 sChapter 9    Connexins as Substrates for Protein Kinases and Phosphoprotein Phosphatases    199! J! w+ @1 w* z7 i
José L. Vega, Elizabeth Baeza, Viviana M. Berthoud and Juan C. Sáez
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VI     Contents
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# E' Y$ {" `$ ~/ U0 o9 bChapter 10     Protein Phosphatases Drive Mitotic Exit    215
2 H4 D  L' V- a; f/ g* eMegan Chircop& X, S8 q* H3 T# m& K

- s. u7 b7 B5 M  _: {Chapter 11   Regulations and Functions of ICK/MAK/MOK – A Novel MAPK-Related Kinase Family Linked 9 K3 N' c9 t( w' f' Y1 _/ u* t
to Human Diseases  229 Zheng “John” Fu& s: P- S9 m' k5 z  U
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Chapter 12     Protein Kinases and Protein Phosphatases
! P7 ?  ^% Q8 E3 ^as Participants in Signal Transduction of Erythrocytes    249
' ?  I  u  u3 A/ }6 Y, \# F% u7 ^Ana Maneva and Lilia Maneva-Radicheva
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, q! U' r8 \& ~- {5 @6 ~, CChapter 13    Role of Protein Kinase Network in
; R  T+ N) B; g, VExcitation-Contraction Coupling in Smooth Muscle Cell    287
2 J) Y  N2 f7 n9 o& T2 G2 HEtienne Roux, Prisca Mbikou and Ales Fajmut1 P! h) P- n$ I2 q4 P7 r8 P4 \( C
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Chapter 14    Regulation of Na+/H+ Exchanger Isoform 3% h- P" E% x$ M  Q" i0 t  C2 ~
by Protein Kinase A in the Renal Proximal Tubule   321
( d( v: [% a7 e& C& c) F  S& _Adriana Castello Costa Girardi and Luciene Regina Carraro-Lacroix$ s# n* P1 Y& H5 u
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Chapter 15     cGMP-Dependent Protein Kinase
  z# i. ]* Y8 g; K3 e" M* xin the Regulation of Cardiovascular Functions  337" L5 @" D1 b8 j4 `$ A$ B1 m3 j
Yuansheng Gao, Dou Dou, Xue Qin, Hui Qi and Lei Ying/ }/ T+ C4 \& d/ V$ ~0 e# W
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Chapter 16    The Crucial Role of c-Src/ J, r: M- T; M2 [/ g5 ~
Tyrosine Kinase in Bone Metabolism    357* T1 @# O; |3 v( ~% T7 @! x( m
Barbara Peruzzi, Nadia Rucci and Anna Teti# p# |$ R3 f4 h" B+ A; v$ z
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Chapter 17     The ERK MAPK Pathway. s0 d, Y, p7 e$ E) z
in Bone and Cartilage Formation   381+ q! I* k5 V9 L( |
Takehiko Matsushita and Shunichi Murakami
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Chapter 18     Protein Kinases and Pancreatic Islet Function    399
0 Y4 b9 v8 d+ k  z' `$ c0 I1 {Gabriela Da Silva Xavier
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Chapter 19   Raf Serine/Threonine Protein Kinases:; M( \4 X# h; |  r* k+ w* C5 g
Immunohistochemical  Localization
: m8 R( J1 ^: nin the Mammalian Nervous System   423( a# D; [2 S  u5 M% A5 r% g
András Mihály
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+ X8 ]' P" ]8 a3 v" |4 E0 e2 ]Chapter 20     Protein Kinases in Spinal Plasticity:
) J5 L9 w. q8 k6 p1 _- k% Z( eA Role for Metabotropic Glutamate Receptors   443
! l. Q) }1 q- i: n0 LJ. Russell Huie and Adam R. Ferguson# Y! g) n0 V- \6 {8 K/ r

3 V! R. w% X  E3 rChapter 21     Protein Kinases and Pain    459
( s, d8 c5 {0 Q( vMani Indiana Funez, Fabiane Hiratsuka Veiga de Souza,; e4 I( u! p$ d
José Eduardo Pandossio, e  r9 H- Q7 {. P& M$ K4 x
and Paulo Gustavo Barboni Dantas Nascimento2 z; }2 G+ W+ S: P/ d

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