PDF电子书：PROTEIN KINASES （2012）

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! k9 t# G# Y5 b4 U# s* kPROTEIN KINASES6 `) R$ V5 K$ ?! U4 h. f/ N
Edited by Gabriela Da Silva Xavier* W% V) s5 M" G2 c; p
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Copyright © 2012 InTech
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Contents! s8 X. b- t' M2 q
Preface   IX
. W6 b0 V1 o/ }, mChapter 1     The Target of Rapamycin: Structure and Functions    1% v) L4 `; h! P5 c6 F3 h1 |8 }
Chang-Chih Wu, Po-Chien Chou and Estela Jacinto
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0 n/ r2 {4 N# sChapter 2     SNF1/AMP-Activated Protein Kinases: Genes, Expression and Biological Role   41& i' B9 t7 E. v) D; K2 N* T. D
Dmytro O. Minchenko and Oleksandr H. Minchenko9 i; a' `$ E" {

& R& E; Z. G# F/ p% {# e7 TChapter 3   Alternating Phosphorylation with O-GlcNAc Modification: Another Way to Control Protein / l6 C6 z* R: i2 q" T
Function   63. g3 c$ }' `& V0 A' W0 s
Victor V. Lima and Rita C. Tostes
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6 A- s2 ]* h  V6 A/ |6 H8 hChapter 4     Technologies for the Use of Protein Kinases into Medical Applications    79 Yoshiki
  \6 f, L" p5 ?# `2 V8 s! `2 YKatayama8 h+ q# w3 Z* B4 c

) g+ ?- ?0 M& {  ?Chapter 5   Role of Kinases and Phosphatases in Host-Pathogen Interactions 99 Horacio Bach: a+ s& b: z; n" F! }0 Y% S

" n& K, c0 y7 c4 b5 XChapter 6   Pathogen Strategies to Evade Innate Immune Response: A Signaling Point of View   123/ c% L' c# S3 O
Bruno Miguel Neves, Maria Celeste Lopes and Maria Teresa Cruz
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Chapter 7 Phosphorylation-Regulated Cell Surface Expression of Membrane Proteins 165 Yukari Okamoto 1 G- E: E: u6 q) d& S6 a
and Sojin Shikano
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Chapter 8   Regulation of Retrotransposition of Long Interspersed Element-13 s. d8 @1 D% D; S5 b& V- R: q. q
by Mitogen-Activated Protein Kinases   187* a8 A* d& B5 u; ?: c
Yukihito Ishizaka, Noriyuki Okudaira and Tadashi Okamura8 J2 F! o+ d( L) r

" u' v4 q6 x- _7 X' {8 ]Chapter 9    Connexins as Substrates for Protein Kinases and Phosphoprotein Phosphatases    199
" F) e- L3 g0 W1 M1 C2 rJosé L. Vega, Elizabeth Baeza, Viviana M. Berthoud and Juan C. Sáez0 L* \' B0 `; G* Y  X% M
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VI     Contents/ L1 E  D4 j7 {; ~. o- n
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Chapter 10     Protein Phosphatases Drive Mitotic Exit    215
' @; ^3 ~" x7 @( FMegan Chircop
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Chapter 11   Regulations and Functions of ICK/MAK/MOK – A Novel MAPK-Related Kinase Family Linked
( Y/ t% P3 E: Pto Human Diseases  229 Zheng “John” Fu# u" [8 o; `5 a8 A5 F2 G- \/ a9 X

( ~9 p* B, V& R, v! T  V) o4 aChapter 12     Protein Kinases and Protein Phosphatases9 o$ W) ~7 i* Y+ @' }8 V$ Z
as Participants in Signal Transduction of Erythrocytes    249
6 N( N8 K5 W! R6 P% y  n1 vAna Maneva and Lilia Maneva-Radicheva
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Chapter 13    Role of Protein Kinase Network in
- h- C$ S, X9 G) `/ B$ VExcitation-Contraction Coupling in Smooth Muscle Cell    2877 W) |" l7 g  G$ f7 J6 m. s1 C4 ?
Etienne Roux, Prisca Mbikou and Ales Fajmut
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( }; F$ X) U* B0 S: b: e  HChapter 14    Regulation of Na+/H+ Exchanger Isoform 33 V3 x5 F' W- b3 E6 }0 Q
by Protein Kinase A in the Renal Proximal Tubule   3210 A/ Z% C4 @- f& w" u
Adriana Castello Costa Girardi and Luciene Regina Carraro-Lacroix
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Chapter 15     cGMP-Dependent Protein Kinase
3 A/ p! S& h* `0 win the Regulation of Cardiovascular Functions  337
+ A( O! S' ~7 o! S; S! t, B8 O  NYuansheng Gao, Dou Dou, Xue Qin, Hui Qi and Lei Ying
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Chapter 16    The Crucial Role of c-Src
' [( P  L* L3 ]$ F5 YTyrosine Kinase in Bone Metabolism    357
( o* L. C$ \* G) p# N/ s- EBarbara Peruzzi, Nadia Rucci and Anna Teti& s2 A! F  K4 M. c  o. e6 T
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Chapter 17     The ERK MAPK Pathway$ Q9 Z1 Q; M1 }/ x7 `0 a  R% N
in Bone and Cartilage Formation   381' X- _1 _  v- x' q# P
Takehiko Matsushita and Shunichi Murakami( f( e; g- W' ^0 Q" _; I. F; V0 C
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Chapter 18     Protein Kinases and Pancreatic Islet Function    399
. V7 j: I" T- |" Y& w; R9 G1 EGabriela Da Silva Xavier& T9 ^: b" n8 c; o
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Chapter 19   Raf Serine/Threonine Protein Kinases:! b9 c  B% _6 N# {, g6 a7 v! E
Immunohistochemical  Localization& n# M2 n/ q/ g+ n' E$ n
in the Mammalian Nervous System   4238 f. g# I/ Q, g# z, n
András Mihály) P  Y6 `( X( G% ]+ H8 k; y

6 q4 q) I% H# E- w0 \$ }" }$ f  _Chapter 20     Protein Kinases in Spinal Plasticity:
4 S# r) P; p# e; ~& H2 k% k! JA Role for Metabotropic Glutamate Receptors   443. Y) {* ~$ Y0 Z, i- p2 J6 E9 K
J. Russell Huie and Adam R. Ferguson9 i- ~, X: B% a1 _. H0 ?! }3 y# L! n
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Chapter 21     Protein Kinases and Pain    459
, T# k( Y( X  q0 L) ^1 w: @Mani Indiana Funez, Fabiane Hiratsuka Veiga de Souza,
6 q1 Z- N$ T  m2 `7 D1 [/ RJosé Eduardo Pandossio2 k. R% F/ U9 T1 D3 S: u
and Paulo Gustavo Barboni Dantas Nascimento) c9 [6 u2 _+ w" L3 B* ^1 x$ L, g

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