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20131月 Nature Cell Biology $ i; E4 r8 J: u a! d1 m" y( d: q+ X/ ~ H' i# @& j 5 `# a1 N0 Q4 x1 BUnderstanding how the deregulation of normal cell biological processes leads to malignant transformation and cancer progression is a major area of research. The Review in this issue is the first in a series of specially commissioned articles discussing current topics and recent advances in this field.5 f+ K# [' v" S: j
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