请教一个信号通路的问题

genedu

XAV-939 这个小分子你可以考虑一下

genedu

ICG-001作用一般，如果方便的话，你也可以试一试

genedu

回复 ind6562 的帖子' p/ f4 i- f# i! N& T, Z4 l

' C0 p8 s  |# m+ ]: Z% Q1.Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.   Nature. 2009 Oct 1;461(7264):614-20. doi: 10.1038/nature08356. Epub 2009 Sep 16
4 z9 V1 o' W- g7 p. c. \+ _2.Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.  Aging (Albany NY). 2010 Oct;2(10):691-708.
0 ~  K$ z( i7 O" R# Y3 k3.Ribosomal Protein S6 Kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein   [Qi Ma,Sunny Guin et al Mol Cancer 2011 May ;10:66]