“吸血鬼疗法”治愈秃顶

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来源：中国日报网 发布时间：2013-5-7 15:56:14 选择字号：小 中 大, S  P) u5 O* r$ w
科学家称找到治疗白发和脱发的有效方法
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7 r: {9 e; m0 B1 V9 V  [' h现实生活中，许多人因白发丛生、头发稀疏甚至局部脱发而苦恼不已。据英国《每日邮报》网站5月6日报道，科学家已经找到治疗白发和脱发的有效方法，上述问题将很快得到解决。; P- j; e% c4 H4 t" w8 `( @
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白发变黑不再是梦
# X, t8 _/ k* I0 {6 c9 l/ q8 V# d3 }为了摆脱白发的困扰，染发已经成为一些人日常生活中不可或缺的组成部分。不过，他们面临的难题很快就能得到解决，因为科学家已经找到“白发变黑”的妙招。
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来自新西兰、德国和英国的科学家们联合研究发现，毛囊中堆积过量过氧化氢导致大规模表皮氧化应激发生，是致使头发由内而外变得灰白的根本原因。这种由内而外的变色过程可以通过一种特殊方法治愈，即经由恰当日晒刺激假触酶产生，进而逆转变色过程，令头发重新恢复自然发色。, |, U9 r5 l2 T0 u. C; Q+ A

7 U" J( u7 C9 N( f( M% A0 s“一直以来，人们都在尝试利用各种方法掩饰自己的白发。现在，能够彻底有效治愈白发的方法产生了！”该研究负责人吉拉德·维斯曼博士表示，类似的疗法还可以被用来治愈白癜风。据悉，已有2411名白癜风病人参与了实验，经过系统治疗后，他们的肤色和睫毛颜色正在逐步恢复正常。9 L7 s: a+ x1 U+ Y: p# W7 f
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维斯曼称，找到一种能够治愈白发和白癜风的有效疗法意义重大，既能恢复患者对于自身外貌的信心，也能在根本上改善他们的生活质量。不过，由于实验尚未完成，所以短时间内无法大范围推广上述疗法。
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“吸血鬼疗法”治愈秃顶
  B9 g9 J2 H- a3 s, T% O随着生活和工作压力越来越大，不少男性的头发日渐稀疏，甚至变得聪明“绝顶”。为了让自己的头发再度茂密起来，他们可真是绞尽了脑汁。日前，科学家宣布治疗秃顶领域的研究取得突破，通过一种“吸血鬼疗法”可以有效刺激头发重新生长。
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/ B. w' ~& N* S; J) W据介绍，所谓“吸血鬼疗法”就是抽取秃顶患者血液，经处理后提取富血小板血浆，然后把这种血浆重新注射回患者体内，从而促进其皮下干细胞再生，进而达到生发的目的。$ |$ w2 E9 E. z# n

9 c3 V: b0 i, u: `此项研究是由国际毛发研究基金会、意大利布雷西亚大学和以色列希伯来大学医学中心共同展开的。45名参加实验的局部脱发患者被分为三组，分别接受“吸血鬼疗法”、传统类固醇乳霜疗法和安慰疗法。实验结果显示，“吸血鬼疗法”效果显著，接受该疗法的患者的头顶均长出了长短不一的新发。: r5 H/ |! V3 N3 c

. K' F: v: n  A3 T. f+ K科学家称，除接受手术治疗进行植发外，这种注射是应对秃顶的最佳治疗法，对男性脱发尤其奏效，“在不远的将来，代替针头的乳霜也有望面世”。& i; q5 q) i. P
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% X- `4 `# M$ u9 lThe vampire 'cure' for baldness: Scientists inject patient's own blood into head to stimulate hair growth') R  N$ h' k: v. ]

• [size=1.4em]Injections of 'platelet-rich plasma' already used to combat ageing on the face and hands
• [size=1.4em]Study on volunteers showed significant hair regrowth on bald spots. N' R  z2 f) F' l( |/ M' c
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By
4 r6 B. a' Z' X: }7 D" xDAILY MAIL REPORTER

[size=0.9em]PUBLISHED:* E; @% M# ~( X& Q. @, z
11:52 GMT, 5 May 20138 d" ]" \7 w0 Y: k! F9 Y
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- h0 U9 s0 d0 @( R5 {[size=0.9em]UPDATED:
( n; m# X$ s8 z8 q1 b' m' {4 E' U4 k08:39 GMT, 6 May 2013

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[size=1.2em]Balding men would do almost anything to have a full head of hair, but the latest 'cure' might be a painful step too far even for them.

[size=1.2em]Scientists have been able to regrow hair on bald patches by injecting the heads of follicular-challenged volunteers with a solution from their own blood.

[size=1.2em]The 'vampire ' treatment stimulates new stem cells below the skin which can assist regrowth, believe researchers.

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Getting the needle: Volunteer patients were injected in the head with a solution of their own blood to stimulate hair regrowth

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[size=1.2em]Injections of 'platelet-rich plasma' (PRP) which have been extracted from the blood, are already used to combat ageing on the face and hands, reported the Sunday Telegraph.

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[size=1.2em]In the latest research by
9 N  g7 W7 @; a$ ?[size=1.2em]scientists4 j/ ^6 `! Z! Y8 U* o* c: W
[size=1.2em]at the International Hair Research Foundation, the University of Brescia in Italy and the Hebrew University Medical Centre in Israel,
1 G1 Z/ [( `* s; p' P, R8 C- U. W* g[size=1.2em]used 45 sufferers with$ S4 b6 `$ r& O
[size=1.2em]alopecia areata, affecting two[size=1.2em]8 O3 J# {8 T" r3 o2 K4 ]
per cent of the population.[size=1.2em]

Bald spot: Scientists believe the new research shows that the injections could be the 'best treatment' available, apart from surgery

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[size=1.2em]The patients had injections on one half of their head. Some were given the PRP, some  traditional steroid cream, while others received a placebo.

[size=1.2em]Three treatments were given every month. Hair growth was checked by measuring the area where new hairs grew on the bald scalp.
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[size=1.2em]Results showed the plasma injections led to significant hair regrowth in the bald patches, compared with the placebo and the steroid treatment.

[size=1.2em]Following the publication of the study in[size=1.2em]
7 c+ \) f) K+ w8 j; |1 Rthe British Journal of Dermatology, the scientists
9 X# S+ W, T8 `: k% e[size=1.2em]are hoping to develop a cream, so needles won't need to be used., Y0 i: c5 [- B$ p+ L3 H, ^

[size=1.2em]Dr Fabio Rinaldi told the Telegraph the new treatment could also help those suffering more common hair problems like male-pattern baldness.

[size=1.2em]He  said: 'We think it can help to regrow hair on people with androgenic alopecia. We believe it is the best treatment available, apart from surgery.'

[size=1.2em]Nina Goad, of the British Association of Dermatologists, said: 'Alopecia is known to lead to overwhelming effects on the patient's quality of life and self-esteem. This could offer hope to thousands.'

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http://www.dailymail.co.uk/sciencetech/article-2319729/Going-bald-Scientists-vampire-cure-involves-injecting-solution-patients-blood-patchy-spot-head.html

milo8008

“富血小板血浆”是什么意思，浓缩血小板还是浓缩血内的促进干细胞生长的成分？7 _% A/ ~0 M0 K

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Further reading: + I- H+ i/ t5 H( ^$ X5 K$ Q+ z' x

8 b5 p( x" l2 P8 M# I! `! p4 NPaper 2: Abstract
6 o' F7 n  k% Q# w5 w3 N" VNonsegmental vitiligo (NSV) is characterized by loss of inherited skin color. The cause of the disease is still unknown despite accumulating in vivo and in vitro evidence of massive epidermal oxidative stress via H2O2 and peroxynitrite (ONOO−) in affected individuals. The most favored hypothesis is based on autoimmune mechanisms. Strictly segmental vitiligo (SSV) with dermatomal distribution is a rare entity, often associated with stable outcome. Recently, it was documented that this form can be associated with NSV (mixed vitiligo). We here asked the question whether ROS and possibly ONOO− could be players in the pathogenesis of SSV. Our in situ results demonstrate for the first time epidermal biopterin accumulation together with significantly decreased epidermal catalase, thioredoxin/thioreoxin reductase, and MSRA/MSRB expression. Moreover, we show epidermal ONOO− accumulation. In vivo FT-Raman spectroscopy reveals the presence of H2O2, methionine sulfoxide, and tryptophan metabolites; i.e., N-formylkynurenine and kynurenine, implying Fenton chemistry in the cascade (n=10). Validation of the basic data stems from successful repigmentation of skin and eyelashes in affected individuals, regardless of SSV or segmental vitiligo in association with NSV after reduction of epidermal H2O2 (n=5). Taken together, our contribution strongly supports H2O2/ONOO-mediated stress in the pathogenesis of SSV. Our findings offer new treatment intervention for lost skin and hair color.—Schallreuter, K. U., Salem, M. A. E. L., Holtz, S., Panske, A. Basic evidence for epidermal H2O2/ONOO−-mediated oxidation/nitration in segmental vitiligo is supported by repigmentation of skin and eyelashes after reduction of epidermal H2O2 with topical NB-UVB-activated pseudocatalase PC-KUS.

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" E. O9 x9 ^$ G- M  ?: zPaper 1- 毛囊中堆积过量过氧化氢导致大规模表皮氧化应激发生，是致使头发由内而外变得灰白的根本原因
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