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: U0 g( ~5 J; Z8 uCOVER Intestinal organoids (red) derived in vitro from single
# y0 K: [3 v5 w: V( C9 M1 C9 Pintestinal stem cells display cryptlike structures with stem and Paneth cells 0 G6 ~. j. w- X2 p+ s
(stem cells, green). Infused mini-guts fill in the ulcerated area of an inflamed
" k/ u& O$ I. ?; a/ ~colon. Reviews in this special issue on morphogenesis describe recent mini-gut ; y3 i( H) |# |/ E) }# O
technology, as well as advances in light dynamics during development. See the
) R/ f: L+ G( K7 ~. l( Aspecial section on page 1183 and at
/ z+ J5 o$ U5 d1 l) \5 l5 Qwww.sciencemag.org/special/morph. , P' f! P; m! p
Image: Hans Clevers, Hubrecht Institute
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