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COVER Intestinal organoids (red) derived in vitro from single
2 b# i/ u& }5 uintestinal stem cells display cryptlike structures with stem and Paneth cells ! F/ K- c. M8 R/ q4 c, C
(stem cells, green). Infused mini-guts fill in the ulcerated area of an inflamed
5 r* [7 _& k' d! ?colon. Reviews in this special issue on morphogenesis describe recent mini-gut $ K+ D3 s: J9 R0 T y
technology, as well as advances in light dynamics during development. See the
! m) e7 h& d; d' J) R% T3 Zspecial section on page 1183 and at 5 I) `& C6 _" S9 v: t1 _$ I/ K4 r4 W
www.sciencemag.org/special/morph. / q" k9 w! ?3 R- c x7 s) _0 ?/ z$ a
Image: Hans Clevers, Hubrecht Institute
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