《细胞》[Cell]13年7月18日出版pdf全文

nero1981

& ^9 E1 \) G8 {! I8 KVolume 154, Issue 23 v- r# w6 j' Q. U. I# a
On the cover: In this issue of Cell, Terasaki et al. (pp. 285–296) ' w( \6 J! l9 }8 f- v
explain how parallel sheets of endoplasmic reticulum are connected. The
( m1 m4 k! p7 J! e  Yexistence of these sheet stacks and their function in synthesis of membrane and
. Y6 E" @5 \  l1 _secreted proteins has been known for more than 60 years. Three-dimensional / |1 t" b5 Y7 C' b1 w: o
reconstructions from serial section electron micrographs from mouse salivary 2 W0 ^+ A2 ~. _) B7 i0 ~& V" r
gland show that the sheets are connected by twisted membrane surfaces with
: d8 I- C/ j% R, rhelical edges. The overall structure resembles a parking garage, in which the
5 M3 L/ a  O5 G& wdifferent levels are connected by helicoidal ramps. Theoretical calculations
; I0 B4 p9 j$ ?% pshow that this structure minimizes the elastic energy of sheet edges and
4 I& u8 [$ D5 ?6 ?! {surfaces and allows dense packing of this organelle in the restricted space of a 3 Q) J$ R! c% `, K" _( L
cell.
7 p( D6 u6 A. l/ a

游客，如果你要查看本帖隐藏内容请回复

exin11

exin11

exin11

回复 nero1981 的帖子# c9 G( a3 j  R' C  v1 s7 i
5 W! ?$ i: F! z# h- \) o
你发错了，这是nature的
+ @; m2 X! O+ N

tpwang

回复 nero1981 的帖子9 R+ c3 b$ D- d( }1 Q

: F% I# l  w. I! h1 d, R" uthanks

chichao0000

ding

chichao0000

请速更改，这是nature  N- y! L/ n. E3 |

osterix

Protein.Arrays,.Biochips,.and.Proteomics

nydfy

THX!!!

zhaoyoungyoung

感谢分享